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GOOD GERMS, BAD GERMS

HEALTH AND SURVIVAL IN A BACTERIAL WORLD

Sachs discusses a variety of proposed solutions for infection as well as allergy, but basically the message is, “Get over...

Chapter and verse on the bugs that outnumber, outwit and no doubt will outlast us.

The good news is that for the most part these bugs, aka bacteria, help or at least do no harm. With us since birth, the resident flora help digest and extract nourishment from what we eat, asking little but leftovers in return. Comfortably lodged in our various niches, they also impede hostile takeovers by the not-so-nice species, which is one reason we suffer diarrhea or other complaints. Sachs (Corpse: Nature, Forensics, and the Struggle to Pinpoint Time of Death, 2001) deals with the well-known problems of human antibiotic abuse that leads to scary headlines about hospital superbugs or extensively drug-resistant tuberculosis, but she also covers the overuse of antibiotics for livestock, which ensures that at least some highly drug-resistant bugs make it to the supermarket. She explains the many ways bacteria acquire resistance: via mutations, but also through the exchange of genes within a strain (bacterial sex) and across species; genes are also ferried into bacteria by invading viruses. Sachs points out that most antibiotics are derived from bacteria species that have a supply of resistance genes sequestered in their main chromosome ready to be turned on to prevent bacterial suicide. Humans’ built-in defenses are largely the components of the immune system, the antibody-producing and killer cells, as well as the ones that trigger allergic sneezes. The latter branch of the system may be in overdrive, she suggests, as we excessively spritz the latest bactericidal sprays and cleaners. This “hygiene hypothesis” posits that the reason for increases in asthma, allergies and autoimmune diseases in the developed world is that the immune system, for want of normal disease-fighting activity, overreacts to any stray molecule it senses, triggering an inflammatory response.

Sachs discusses a variety of proposed solutions for infection as well as allergy, but basically the message is, “Get over it! Learn to live and let live in a natural balance.”

Pub Date: Oct. 1, 2007

ISBN: 978-0-8090-5063-5

Page Count: 336

Publisher: Hill and Wang/Farrar, Straus and Giroux

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: July 15, 2007

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WHY WE SWIM

An absorbing, wide-ranging story of humans’ relationship with the water.

A study of swimming as sport, survival method, basis for community, and route to physical and mental well-being.

For Bay Area writer Tsui (American Chinatown: A People's History of Five Neighborhoods, 2009), swimming is in her blood. As she recounts, her parents met in a Hong Kong swimming pool, and she often visited the beach as a child and competed on a swim team in high school. Midway through the engaging narrative, the author explains how she rejoined the team at age 40, just as her 6-year-old was signing up for the first time. Chronicling her interviews with scientists and swimmers alike, Tsui notes the many health benefits of swimming, some of which are mental. Swimmers often achieve the “flow” state and get their best ideas while in the water. Her travels took her from the California coast, where she dove for abalone and swam from Alcatraz back to San Francisco, to Tokyo, where she heard about the “samurai swimming” martial arts tradition. In Iceland, she met Guðlaugur Friðþórsson, a local celebrity who, in 1984, survived six hours in a winter sea after his fishing vessel capsized, earning him the nickname “the human seal.” Although humans are generally adapted to life on land, the author discovered that some have extra advantages in the water. The Bajau people of Indonesia, for instance, can do 10-minute free dives while hunting because their spleens are 50% larger than average. For most, though, it’s simply a matter of practice. Tsui discussed swimming with Dara Torres, who became the oldest Olympic swimmer at age 41, and swam with Kim Chambers, one of the few people to complete the daunting Oceans Seven marathon swim challenge. Drawing on personal experience, history, biology, and social science, the author conveys the appeal of “an unflinching giving-over to an element” and makes a convincing case for broader access to swimming education (372,000 people still drown annually).

An absorbing, wide-ranging story of humans’ relationship with the water.

Pub Date: April 14, 2020

ISBN: 978-1-61620-786-1

Page Count: 288

Publisher: Algonquin

Review Posted Online: Jan. 4, 2020

Kirkus Reviews Issue: Feb. 1, 2020

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THE IMMORTAL LIFE OF HENRIETTA LACKS

Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and...

A dense, absorbing investigation into the medical community's exploitation of a dying woman and her family's struggle to salvage truth and dignity decades later.

In a well-paced, vibrant narrative, Popular Science contributor and Culture Dish blogger Skloot (Creative Writing/Univ. of Memphis) demonstrates that for every human cell put under a microscope, a complex life story is inexorably attached, to which doctors, researchers and laboratories have often been woefully insensitive and unaccountable. In 1951, Henrietta Lacks, an African-American mother of five, was diagnosed with what proved to be a fatal form of cervical cancer. At Johns Hopkins, the doctors harvested cells from her cervix without her permission and distributed them to labs around the globe, where they were multiplied and used for a diverse array of treatments. Known as HeLa cells, they became one of the world's most ubiquitous sources for medical research of everything from hormones, steroids and vitamins to gene mapping, in vitro fertilization, even the polio vaccine—all without the knowledge, must less consent, of the Lacks family. Skloot spent a decade interviewing every relative of Lacks she could find, excavating difficult memories and long-simmering outrage that had lay dormant since their loved one's sorrowful demise. Equal parts intimate biography and brutal clinical reportage, Skloot's graceful narrative adeptly navigates the wrenching Lack family recollections and the sobering, overarching realities of poverty and pre–civil-rights racism. The author's style is matched by a methodical scientific rigor and manifest expertise in the field.

Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and Petri dish politics.

Pub Date: Feb. 9, 2010

ISBN: 978-1-4000-5217-2

Page Count: 320

Publisher: Crown

Review Posted Online: Dec. 22, 2010

Kirkus Reviews Issue: Jan. 1, 2010

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