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PANDORA'S DNA

TRACING THE BREAST CANCER GENES THROUGH HISTORY, SCIENCE, AND ONE FAMILY TREE

A gutsy, deeply revealing account that more than fulfills the promise of the subtitle.

Freelance journalist and author Stark (Leaving Mundania: Inside the Transformative World of Live Action Role-Playing Games, 2012) has both fully researched her subject and poured out her heart in this blend of history, science and memoir.

As the family tree in the book’s front shows, cancer, and the threat of cancer, has plagued the author’s family for generations. When she underwent genetic testing and learned that she had inherited her mother’s BRCA1 mutation, which greatly raises the risks of both breast and ovarian cancers, Stark was well-aware of its significance. After coping with the hassles of close monitoring, she made the tough decision to have a preventative double mastectomy while still in her 20s. The story of that decision and all that follows from it is enough to make a book in itself, but the author goes much further. She provides a capsule history of breast surgery, from the pre-anesthesia days through William Halsted’s now-outdated radical mastectomy to today’s less disfiguring procedures, and she profiles geneticist Mary-Claire King, whose work led to the identification of the BRCA genes. In her discussion of the controversial issue of gene patenting, Stark presents all sides of the argument. Most impressive, she tells her personal story with considerable frankness and flashes of humor. The weekend before her breast-removal surgery, she and her husband threw a “goodbye to boobs” party for their closest friends. That lighthearted moment is followed by less sunny ones as Stark was forced to adjust to her new body and face the questions of whether to bear children and possibly pass on the gene mutation and deciding when to have her threatened ovaries removed. The book is a must-read for women questioning whether to be tested for the BRCA mutations and for women considering their options after testing positive.

A gutsy, deeply revealing account that more than fulfills the promise of the subtitle.

Pub Date: Oct. 15, 2014

ISBN: 978-1613748602

Page Count: 336

Publisher: Chicago Review Press

Review Posted Online: Aug. 26, 2014

Kirkus Reviews Issue: Sept. 15, 2014

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BETWEEN THE WORLD AND ME

NOTES ON THE FIRST 150 YEARS IN AMERICA

This moving, potent testament might have been titled “Black Lives Matter.” Or: “An American Tragedy.”

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  • Pulitzer Prize Finalist

The powerful story of a father’s past and a son’s future.

Atlantic senior writer Coates (The Beautiful Struggle: A Father, Two Sons, and an Unlikely Road to Manhood, 2008) offers this eloquent memoir as a letter to his teenage son, bearing witness to his own experiences and conveying passionate hopes for his son’s life. “I am wounded,” he writes. “I am marked by old codes, which shielded me in one world and then chained me in the next.” Coates grew up in the tough neighborhood of West Baltimore, beaten into obedience by his father. “I was a capable boy, intelligent and well-liked,” he remembers, “but powerfully afraid.” His life changed dramatically at Howard University, where his father taught and from which several siblings graduated. Howard, he writes, “had always been one of the most critical gathering posts for black people.” He calls it The Mecca, and its faculty and his fellow students expanded his horizons, helping him to understand “that the black world was its own thing, more than a photo-negative of the people who believe they are white.” Coates refers repeatedly to whites’ insistence on their exclusive racial identity; he realizes now “that nothing so essentialist as race” divides people, but rather “the actual injury done by people intent on naming us, intent on believing that what they have named matters more than anything we could ever actually do.” After he married, the author’s world widened again in New York, and later in Paris, where he finally felt extricated from white America’s exploitative, consumerist dreams. He came to understand that “race” does not fully explain “the breach between the world and me,” yet race exerts a crucial force, and young blacks like his son are vulnerable and endangered by “majoritarian bandits.” Coates desperately wants his son to be able to live “apart from fear—even apart from me.”

This moving, potent testament might have been titled “Black Lives Matter.” Or: “An American Tragedy.”

Pub Date: July 8, 2015

ISBN: 978-0-8129-9354-7

Page Count: 176

Publisher: Spiegel & Grau

Review Posted Online: May 5, 2015

Kirkus Reviews Issue: July 1, 2015

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NIGHT

The author's youthfulness helps to assure the inevitable comparison with the Anne Frank diary although over and above the...

Elie Wiesel spent his early years in a small Transylvanian town as one of four children. 

He was the only one of the family to survive what Francois Maurois, in his introduction, calls the "human holocaust" of the persecution of the Jews, which began with the restrictions, the singularization of the yellow star, the enclosure within the ghetto, and went on to the mass deportations to the ovens of Auschwitz and Buchenwald. There are unforgettable and horrifying scenes here in this spare and sombre memoir of this experience of the hanging of a child, of his first farewell with his father who leaves him an inheritance of a knife and a spoon, and of his last goodbye at Buchenwald his father's corpse is already cold let alone the long months of survival under unconscionable conditions. 

The author's youthfulness helps to assure the inevitable comparison with the Anne Frank diary although over and above the sphere of suffering shared, and in this case extended to the death march itself, there is no spiritual or emotional legacy here to offset any reader reluctance.

Pub Date: Jan. 16, 2006

ISBN: 0374500010

Page Count: 120

Publisher: Hill & Wang

Review Posted Online: Oct. 7, 2011

Kirkus Reviews Issue: Jan. 15, 2006

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