Moalem’s lively and enthusiastic treatise offers enough plausible explanations for interesting phenomena that you’ll be...
Certain disease-related genes may make you sick but protect you from a worse fate—death—argues unconventional medical researcher Moalem.
Currently completing his training at Mount Sinai School of Medicine (he already has a Ph.D. in neurogenetics and evolutionary medicine), the author includes many examples to support his contention that “one man’s disease is another man’s cure.” People with a genetic tendency for sickle-cell anemia, for example, have better natural resistance to malaria. Moalem provides evidence that a hereditary condition called hemochromatosis, which causes iron to build up in the body, may have arisen to protect people from plague and that vulnerability to diabetes may have been an adaptation to ice ages. The accumulation of sugar in blood made more concentrated by frequent urination lowers the freezing point so people don’t freeze to death, he asserts. Dark-skinned people moving to northern climates may be more susceptible to heart disease because they carry genes for the excess cholesterol they needed in areas of intense sunlight. Other sections describe how plants and animals co-evolve as they adapt to climate changes and how a parasite like the Guinea worm “manipulates its victims to collaborate in the infection of others.” We should use such knowledge to develop new strategies to defeat parasites rather than relying on drugs, Moalem suggests. He sees hope for ways to combat cancer that involve turning on or off selected genes—indeed, he has much to say about the dynamism of the human genome. The final chapters report research suggesting that environmental events in early pregnancy may have far-reaching effects on offspring. The author also takes seriously Elaine Morgan’s idea that human evolution may have involved an aquatic phase.
Moalem’s lively and enthusiastic treatise offers enough plausible explanations for interesting phenomena that you’ll be willing to forgive its more outré speculations.Pub Date: Feb. 6, 2007
ISBN: 0-06-088965-9
Page Count: 288
Publisher: Morrow/HarperCollins
Review Posted Online: May 19, 2010
Kirkus Reviews Issue: Dec. 1, 2006
An absorbing, wide-ranging story of humans’ relationship with the water.
A study of swimming as sport, survival method, basis for community, and route to physical and mental well-being.
For Bay Area writer Tsui (American Chinatown: A People's History of Five Neighborhoods, 2009), swimming is in her blood. As she recounts, her parents met in a Hong Kong swimming pool, and she often visited the beach as a child and competed on a swim team in high school. Midway through the engaging narrative, the author explains how she rejoined the team at age 40, just as her 6-year-old was signing up for the first time. Chronicling her interviews with scientists and swimmers alike, Tsui notes the many health benefits of swimming, some of which are mental. Swimmers often achieve the “flow” state and get their best ideas while in the water. Her travels took her from the California coast, where she dove for abalone and swam from Alcatraz back to San Francisco, to Tokyo, where she heard about the “samurai swimming” martial arts tradition. In Iceland, she met Guðlaugur Friðþórsson, a local celebrity who, in 1984, survived six hours in a winter sea after his fishing vessel capsized, earning him the nickname “the human seal.” Although humans are generally adapted to life on land, the author discovered that some have extra advantages in the water. The Bajau people of Indonesia, for instance, can do 10-minute free dives while hunting because their spleens are 50% larger than average. For most, though, it’s simply a matter of practice. Tsui discussed swimming with Dara Torres, who became the oldest Olympic swimmer at age 41, and swam with Kim Chambers, one of the few people to complete the daunting Oceans Seven marathon swim challenge. Drawing on personal experience, history, biology, and social science, the author conveys the appeal of “an unflinching giving-over to an element” and makes a convincing case for broader access to swimming education (372,000 people still drown annually).
An absorbing, wide-ranging story of humans’ relationship with the water.Pub Date: April 14, 2020
ISBN: 978-1-61620-786-1
Page Count: 288
Publisher: Algonquin
Review Posted Online: Jan. 4, 2020
Kirkus Reviews Issue: Feb. 1, 2020
BOOK REVIEW
BOOK REVIEW
Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and...
A dense, absorbing investigation into the medical community's exploitation of a dying woman and her family's struggle to salvage truth and dignity decades later.
In a well-paced, vibrant narrative, Popular Science contributor and Culture Dish blogger Skloot (Creative Writing/Univ. of Memphis) demonstrates that for every human cell put under a microscope, a complex life story is inexorably attached, to which doctors, researchers and laboratories have often been woefully insensitive and unaccountable. In 1951, Henrietta Lacks, an African-American mother of five, was diagnosed with what proved to be a fatal form of cervical cancer. At Johns Hopkins, the doctors harvested cells from her cervix without her permission and distributed them to labs around the globe, where they were multiplied and used for a diverse array of treatments. Known as HeLa cells, they became one of the world's most ubiquitous sources for medical research of everything from hormones, steroids and vitamins to gene mapping, in vitro fertilization, even the polio vaccine—all without the knowledge, must less consent, of the Lacks family. Skloot spent a decade interviewing every relative of Lacks she could find, excavating difficult memories and long-simmering outrage that had lay dormant since their loved one's sorrowful demise. Equal parts intimate biography and brutal clinical reportage, Skloot's graceful narrative adeptly navigates the wrenching Lack family recollections and the sobering, overarching realities of poverty and pre–civil-rights racism. The author's style is matched by a methodical scientific rigor and manifest expertise in the field.
Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and Petri dish politics.Pub Date: Feb. 9, 2010
ISBN: 978-1-4000-5217-2
Page Count: 320
Publisher: Crown
Review Posted Online: Dec. 22, 2010
Kirkus Reviews Issue: Jan. 1, 2010
BOOK REVIEW
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