An engaging and comprehensive analysis of genetic theory with occasional lapses into technophobia.

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THE IMPACT OF THE GENE

FROM MENDEL’S PEAS TO DESIGNER BABIES

A sprawling exploration of genetic theory, as traced from Gregor Mendel’s ideas of heredity and Charles Darwin’s concept of evolution to today’s biotechnologies.

The possibility and the ethics of breeding “better” humans is at the heart of Tudge’s (The Second Creation, 2000) latest work: “When anything is possible, we have to ask as a matter of urgency: So what is right?” Gregor Mendel spent eight years hybridizing garden peas and analyzing hereditary factors; his work laid the foundations of modern genetics. Yet his scientific contributions went unrecognized during his lifetime, in part because of an existing religious climate that was at odds with the scientific community. Just as Christian orthodoxy deeply influenced the climate of Mendel’s mid-19th century, so, too, does Tudge’s rhetoric conflate modern biotechnology with hubris. He discusses two trends in genetics: preventive medicine and transformative technology. In the first, medical knowledge is used to reduce the impact of single-gene disorders, such as cystic fibrosis or Tay-Sachs disease, in a single individual. In the second, genetic technology (in theory) could be used to correct genetic defects in embryos in vitro, an action that would affect subsequent generations. While supportive of the alleviation of suffering, Tudge is opposed to manipulation of the species, and he deems those so interested as selfish and morally perverse. His study contains many interesting details, especially in the chapters discussing Mendel’s work and how his resulting trials ran afoul of university examiners during his repeated attempts to receive a doctorate and teaching credentials. Also interesting are the author’s thoughts on how biotechnology can help the wildlife conservation effort, and what the concept of “designer babies” could entail. His inquiries into the morality of biotechnology rely heavily on his own personal feelings, however, and are likely to strike many readers as unconvincing.

An engaging and comprehensive analysis of genetic theory with occasional lapses into technophobia.

Pub Date: July 1, 2001

ISBN: 0-374-17523-3

Page Count: 256

Publisher: Hill and Wang/Farrar, Straus and Giroux

Review Posted Online: May 20, 2010

Kirkus Reviews Issue: May 1, 2001

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THE RIGHT STUFF

Yes: it's high time for a de-romanticized, de-mythified, close-up retelling of the U.S. Space Program's launching—the inside story of those first seven astronauts.

But no: jazzy, jivey, exclamation-pointed, italicized Tom Wolfe "Mr. Overkill" hasn't really got the fight stuff for the job. Admittedly, he covers all the ground. He begins with the competitive, macho world of test pilots from which the astronauts came (thus being grossly overqualified to just sit in a controlled capsule); he follows the choosing of the Seven, the preparations for space flight, the flights themselves, the feelings of the wives; and he presents the breathless press coverage, the sudden celebrity, the glorification. He even throws in some of the technology. But instead of replacing the heroic standard version with the ring of truth, Wolfe merely offers an alternative myth: a surreal, satiric, often cartoony Wolfe-arama that, especially since there isn't a bit of documentation along the way, has one constantly wondering if anything really happened the way Wolfe tells it. His astronauts (referred to as "the brethren" or "The True Brothers") are obsessed with having the "right stuff" that certain blend of guts and smarts that spells pilot success. The Press is a ravenous fool, always referred to as "the eternal Victorian Gent": when Walter Cronkite's voice breaks while reporting a possible astronaut death, "There was the Press the Genteel Gent, coming up with the appropriate emotion. . . live. . . with no prompting whatsoever!" And, most off-puttingly, Wolfe presumes to enter the minds of one and all: he's with near-drowing Gus Grissom ("Cox. . . That face up there!—it's Cox. . . Cox knew how to get people out of here! . . . Cox! . . ."); he's with Betty Grissom angry about not staying at Holiday Inn ("Now. . . they truly owed her"); and, in a crude hatchet-job, he's with John Glenn furious at Al Shepard's being chosen for the first flight, pontificating to the others about their licentious behavior, or holding onto his self-image during his flight ("Oh, yes! I've been here before! And I am immune! I don't get into corners I can't get out of! . . . The Presbyterian Pilot was not about to foul up. His pipeline to dear Lord could not be clearer"). Certainly there's much here that Wolfe is quite right about, much that people will be interested in hearing: the P-R whitewash of Grissom's foul-up, the Life magazine excesses, the inter-astronaut tensions. And, for those who want to give Wolfe the benefit of the doubt throughout, there are emotional reconstructions that are juicily shrill.

But most readers outside the slick urban Wolfe orbit will find credibility fatally undermined by the self-indulgent digressions, the stylistic excesses, and the broadly satiric, anti-All-American stance; and, though The Right Stuff has enough energy, sass, and dirt to attract an audience, it mostly suggests that until Wolfe can put his subject first and his preening writing-persona second, he probably won't be a convincing chronicler of anything much weightier than radical chic.

Pub Date: Sept. 24, 1979

ISBN: 0312427565

Page Count: 370

Publisher: Farrar, Straus and Giroux

Review Posted Online: Oct. 13, 2011

Kirkus Reviews Issue: Sept. 1, 1979

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Jahren transcends both memoir and science writing in this literary fusion of both genres.

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LAB GIRL

Award-winning scientist Jahren (Geology and Geophysics/Univ. of Hawaii) delivers a personal memoir and a paean to the natural world.

The author’s father was a physics and earth science teacher who encouraged her play in the laboratory, and her mother was a student of English literature who nurtured her love of reading. Both of these early influences engrossingly combine in this adroit story of a dedication to science. Jahren’s journey from struggling student to struggling scientist has the narrative tension of a novel and characters she imbues with real depth. The heroes in this tale are the plants that the author studies, and throughout, she employs her facility with words to engage her readers. We learn much along the way—e.g., how the willow tree clones itself, the courage of a seed’s first root, the symbiotic relationship between trees and fungi, and the airborne signals used by trees in their ongoing war against insects. Trees are of key interest to Jahren, and at times she waxes poetic: “Each beginning is the end of a waiting. We are each given exactly one chance to be. Each of us is both impossible and inevitable. Every replete tree was first a seed that waited.” The author draws many parallels between her subjects and herself. This is her story, after all, and we are engaged beyond expectation as she relates her struggle in building and running laboratory after laboratory at the universities that have employed her. Present throughout is her lab partner, a disaffected genius named Bill, whom she recruited when she was a graduate student at Berkeley and with whom she’s worked ever since. The author’s tenacity, hope, and gratitude are all evident as she and Bill chase the sweetness of discovery in the face of the harsh economic realities of the research scientist.

Jahren transcends both memoir and science writing in this literary fusion of both genres.

Pub Date: April 5, 2016

ISBN: 978-1-101-87493-6

Page Count: 336

Publisher: Knopf

Review Posted Online: Jan. 5, 2016

Kirkus Reviews Issue: Jan. 15, 2016

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