High-quality advocacy certain to stir debate.
The president and CEO of the Goldwater Institute makes a convincing case that the slow pace of the Federal Drug Administration's development and approval process for new medications is needlessly costing lives.
Throughout this forceful book, Olsen cites troubling statistics that underscore the depth of what she claims is a worsening problem. “The FDA,” she writes, “takes as long as 15 years to bring a new medicine to market and Americans are now waiting 60 percent longer for the FDA to approve life-saving medical devices—such as stents and valves—than they did just seven years ago.” This is particularly disturbing in the case of patients with serious illnesses who are denied access to promising new treatments. According to the author, one cause of the problem is asymmetry in the approval process. The FDA is incentivized to be overcautious. If someone dies after undergoing a new treatment approved by the agency, there is a scandal; however, there is insufficient attention paid to deaths attributable to delayed approval. “Instead of speeding medical innovation,” writes Olsen, “the FDA is slowing it down—demanding more data, more tests, and more procedures on more subjects before it will approve a drug.” In some cases, of course, more data and more tests are warranted. But though “American patients used to be the first to benefit from their country's enormous investments in basic medical research,” that is no longer the case. The author presents case histories of patients fortunate enough to be enrolled in FDA-approved trials, many of whom experienced remarkable cures. For terminally ill patients, the odds that an experimental drug will help, though as low as 20 percent, may still be attractive. Olsen’s organization is leading a bipartisan campaign to pass Right to Try legislation allowing patients and their doctors to bypass FDA regulations in deciding whether or not to try experimental treatments and for drug companies to make them available on a compassionate basis.
High-quality advocacy certain to stir debate.Pub Date: Nov. 10, 2015
ISBN: 978-0-06-240752-8
Page Count: 304
Publisher: Harper/HarperCollins
Review Posted Online: Sept. 2, 2015
Kirkus Reviews Issue: Sept. 15, 2015
Bernstein and Woodward, the two Washington Post journalists who broke the Big Story, tell how they did it by old fashioned seat-of-the-pants reporting — in other words, lots of intuition and a thick stack of phone numbers. They've saved a few scoops for the occasion, the biggest being the name of their early inside source, the "sacrificial lamb" H**h Sl**n. But Washingtonians who talked will be most surprised by the admission that their rumored contacts in the FBI and elsewhere never existed; many who were telephoned for "confirmation" were revealing more than they realized. The real drama, and there's plenty of it, lies in the private-eye tactics employed by Bernstein and Woodward (they refer to themselves in the third person, strictly on a last name basis). The centerpiece of their own covert operation was an unnamed high government source they call Deep Throat, with whom Woodward arranged secret meetings by positioning the potted palm on his balcony and through codes scribbled in his morning newspaper. Woodward's wee hours meetings with Deep Throat in an underground parking garage are sheer cinema: we can just see Robert Redford (it has to be Robert Redford) watching warily for muggers and stubbing out endless cigarettes while Deep Throat spills the inside dope about the plumbers. Then too, they amass enough seamy detail to fascinate even the most avid Watergate wallower — what a drunken and abusive Mitchell threatened to do to Post publisher Katherine Graham's tit, and more on the Segretti connection — including the activities of a USC campus political group known as the Ratfuckers whose former members served as a recruiting pool for the Nixon White House. As the scandal goes public and out of their hands Bernstein and Woodward seem as stunned as the rest of us at where their search for the "head ratfucker" has led. You have to agree with what their City Editor Barry Sussman realized way back in the beginning — "We've never had a story like this. Just never."
Pub Date: June 18, 1974
ISBN: 0671894412
Page Count: 372
Publisher: Simon & Schuster
Review Posted Online: Oct. 10, 2011
Kirkus Reviews Issue: June 1, 1974
Less a sequel than an addendum, the book offers a close-up view of the Oval Office in its darkest hour.
Four decades after Watergate shook America, journalist Woodward (The Price of Politics, 2012, etc.) returns to the scandal to profile Alexander Butterfield, the Richard Nixon aide who revealed the existence of the Oval Office tapes and effectively toppled the presidency.
Of all the candidates to work in the White House, Butterfield was a bizarre choice. He was an Air Force colonel and wanted to serve in Vietnam. By happenstance, his colleague H.R. Haldeman helped Butterfield land a job in the Nixon administration. For three years, Butterfield worked closely with the president, taking on high-level tasks and even supervising the installation of Nixon’s infamous recording system. The writing here is pure Woodward: a visual, dialogue-heavy, blow-by-blow account of Butterfield’s tenure. The author uses his long interviews with Butterfield to re-create detailed scenes, which reveal the petty power plays of America’s most powerful men. Yet the book is a surprisingly funny read. Butterfield is passive, sensitive, and dutiful, the very opposite of Nixon, who lets loose a constant stream of curses, insults, and nonsensical bluster. Years later, Butterfield seems conflicted about his role in such an eccentric presidency. “I’m not trying to be a Boy Scout and tell you I did it because it was the right thing to do,” Butterfield concedes. It is curious to see Woodward revisit an affair that now feels distantly historical, but the author does his best to make the story feel urgent and suspenseful. When Butterfield admitted to the Senate Select Committee that he knew about the listening devices, he felt its significance. “It seemed to Butterfield there was absolute silence and no one moved,” writes Woodward. “They were still and quiet as if they were witnessing a hinge of history slowly swinging open….It was as if a bare 10,000 volt cable was running through the room, and suddenly everyone touched it at once.”
Less a sequel than an addendum, the book offers a close-up view of the Oval Office in its darkest hour.Pub Date: Oct. 13, 2015
ISBN: 978-1-5011-1644-5
Page Count: 304
Publisher: Simon & Schuster
Review Posted Online: Oct. 20, 2015
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