One can hope, however, that Davis’s book will assure that proper attention is paid.
Cancer remains such a prolific killer, says the author, because the medical community focuses on treatment rather than prevention of the root causes.
Davis (When Smoke Ran Like Water: Tales of Environmental Deception and the Battle Against Pollution, 2002, etc.), an epidemiologist and director of the Center for Environmental Oncology at University of Pittsburgh’s Cancer Institute, offers a detailed history of workplace and environmental carcinogens that predates Nixon’s “war” on cancer in the ’70s. She reminds us of Sir Percival Pott’s observations of scrotal cancers in English chimney sweeps, the radiation-induced cancers that followed the discovery of X-rays, the Curies’ work with radium and, less well-known, the research of Nazi scientists who linked tobacco to cancer and led officials to discourage Germans from smoking during World War II. The German scientists were pioneers in the new field of epidemiology, which even today is denigrated by some since it involves methods like surveys (unreliable) and statistics (suspect). Much of the text makes for grim but fascinating reading as Davis reviews the tobacco story and describes conditions in steel mills, copper smelters, chemical factories and plastics plants, where workers are exposed to insidious and lethal solvents and agents such as asbestos, benzene, formaldehyde and dioxin. She also immortalizes the many poor people in small towns next to waste dumps or downstream from hugely polluted rivers who died from cancer or whose children suffered birth defects. In almost every case, the offending corporation lied, denied, delayed or bought-off complaints, recruiting the best legal talent and, sad to say, even highly respected scientists. Rather than engage in what has been a fruitless battle of litigation, vengeance and counterproductive legislation, Davis proposes a kind of truth-and-reconciliation approach to get industry and public-health experts mutually involved. But she notes that, unfortunately, it’s simply not happening fast enough, and she goes on to raise her own concerns about cell phones, Ritalin and aspartame.
One can hope, however, that Davis’s book will assure that proper attention is paid.Pub Date: Oct. 1, 2007
ISBN: 978-0-465-01566-5
Page Count: 304
Publisher: Basic Books
Review Posted Online: May 19, 2010
Kirkus Reviews Issue: Aug. 15, 2007
Useful but disappointingly commonplace tips.
In a follow-up to The End of Illness (2012), which explored how technological advances will transform medicine, Agus (Medicine and Engineering/Univ. of Southern California) restates time-tested but too often overlooked principles for healthy living.
The author outlines simple measures that average citizens can take to live healthier lives and extend their life spans by taking advantage of modern technology to develop personalized records. These would include a list of medical tests and recommended treatments. Agus also suggests keeping track of indicators that can be observed at home on a regular basis—e.g., changes in energy, weight, appetite and blood pressure, blood sugar and general appearance. He advises that all of this information be made available online, and it is also helpful to investigate family history and consider DNA testing where indicated. Along with maintaining a healthy weight, Agus emphasizes the importance of eating a balanced diet, with plenty of fresh fruits and vegetables and a minimum of red meat. Avoid packaged vitamins and food supplements, and if possible, grow your own vegetables or buy frozen vegetables, which will generally be fresher than those on supermarket shelves. The author also warns against processed foods that make health claims but contain additives or excessive amounts of sugar or fat. Regular mealtimes and plenty of sleep, frequent hand-washing and oral hygiene are a must; smoking and excessive time in the sun should also be avoided. Agus recommends that adults should consider taking statins and baby aspirin as preventative measures. He concludes with a decade-by-decade checklist of annual medical examinations that should be routine—e.g. blood pressure, diabetes and cholesterol screenings, from one’s 20s on; colonoscopies, prostate exams and mammograms later—and a variety of top-10 lists (for example, “Top 10 Reasons to Take a Walk”).
Useful but disappointingly commonplace tips.Pub Date: Jan. 7, 2014
ISBN: 978-1-4767-3095-0
Page Count: 128
Publisher: Simon & Schuster
Review Posted Online: Sept. 30, 2013
Kirkus Reviews Issue: Oct. 15, 2013
BOOK REVIEW
BOOK REVIEW
Oncologist Agus (Medicine and Engineering/Univ. of Southern California) predicts that the application of advanced technology for modeling complex systems will transform 21st-century medicine.
The author writes that a remark Nobel Laureate Murray Gell-Mann made to him in 2009—“Look at cancer as a system"—transformed the way he views his own specialty and the entire field of preventative medicine. It made him realize that “[r]ather than honoring the body as the exceedingly complex system that it is, we keep looking for the individual gene that has gone awry, or for the one ‘secret’ that can improve our health.” Agus writes that although the ability to sequence the entire human genome is a great step forward, it is insufficient for achieving a significant breakthrough. Even though it may start with a mutation, cancer “is a dynamic process that's happening…far from the confines of a static piece of DNA”—it involves the body's immune system, its ability to regulate cell growth, metabolism and more. Agus directs his university’s Center for Applied Molecular Medicine and is the co-founder of two personalized medicine companies, Applied Proteomics and Navigenics. His hope is that their research will contribute to developing better analytical tools for preventative medicine and for the treatment of cancers. These will address the functioning of the body as a whole, applying digital technology already used by physicists to provide virtual models of cancers and model the action of proteins that regulate cell communication in the body. He also hopes to develop tools that will provide information on the concentration of different proteins in a drop of blood taken from a patient, which may reveal the onset of disease. The author also includes some guiding principles and warnings about certain healthy practices that may not be so healthy. A refreshing change of pace in the medical field, but by venturing beyond his field of expertise to pontificate on a wide range of subjects, Agus makes his otherwise intriguing narrative difficult to follow.
Pub Date: Jan. 1, 2012
ISBN: 978-1-4516-1017-8
Page Count: 288
Publisher: Free Press
Review Posted Online: Nov. 5, 2011
Kirkus Reviews Issue: Nov. 15, 2011
BOOK REVIEW
BOOK REVIEW
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