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THE DISORDERED MIND

WHAT UNUSUAL BRAINS TELL US ABOUT OURSELVES

Synaptic pruning, folded proteins, adaptive habits: all fascinating stuff ably interpreted by a master.

The eminent neuroscientist examines what the injured or diseased brain can tell us about a healthy one.

“Today, as never before, the study of brain disorders is giving us new insight into how our mind normally functions,” writes Nobel Prize winner Kandel (Neuroscience/Columbia Univ.; Reductionism in Art and Brain Science: Bridging the Two Cultures, 2016, etc.). That “normal function” is a complex process involving many parts of the brain, reflecting the emergent fact that consciousness is not a single function of the brain but instead a continuum of “different states of minds in different contexts.” Complex cognitive skills such as understanding speech require input from several widely separated areas of the brain, including the arcuate fasciculus and Broca’s area, while the generation and execution of emotion involve the hypothalamus, striatum, prefrontal cortex, and one tiny part of the brain whose functions are just being understood: “When we laugh or cry—when we experience any emotion—it is because these brain structures are responding to the amygdala, and acting on its instructions.” But just so, writes Kandel, problems such as addiction also involve several brain regions and neural circuits, requiring multiple approaches to any neuroscientific regime of treatment. Autism is another such area, manifesting itself in failures in the complex problem of interpreting “biological motion,” which in turn “enables us to recognize intention, which is critical to a theory of mind.” In the end, understanding various states of brain function in varying degrees of health helps address not just the question of consciousness, modern theories of which Kandel addresses in closing, but also the much larger issue of human nature and what it entails. Throughout, the author writes accessibly, though it may help readers to have some background in neuroscience and anatomy.

Synaptic pruning, folded proteins, adaptive habits: all fascinating stuff ably interpreted by a master.

Pub Date: Aug. 28, 2018

ISBN: 978-0-374-28786-3

Page Count: 304

Publisher: Farrar, Straus and Giroux

Review Posted Online: May 14, 2018

Kirkus Reviews Issue: June 1, 2018

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MASTERY

Readers unfamiliar with the anecdotal material Greene presents may find interesting avenues to pursue, but they should...

Greene (The 33 Strategies of War, 2007, etc.) believes that genius can be learned if we pay attention and reject social conformity.

The author suggests that our emergence as a species with stereoscopic, frontal vision and sophisticated hand-eye coordination gave us an advantage over earlier humans and primates because it allowed us to contemplate a situation and ponder alternatives for action. This, along with the advantages conferred by mirror neurons, which allow us to intuit what others may be thinking, contributed to our ability to learn, pass on inventions to future generations and improve our problem-solving ability. Throughout most of human history, we were hunter-gatherers, and our brains are engineered accordingly. The author has a jaundiced view of our modern technological society, which, he writes, encourages quick, rash judgments. We fail to spend the time needed to develop thorough mastery of a subject. Greene writes that every human is “born unique,” with specific potential that we can develop if we listen to our inner voice. He offers many interesting but tendentious examples to illustrate his theory, including Einstein, Darwin, Mozart and Temple Grandin. In the case of Darwin, Greene ignores the formative intellectual influences that shaped his thought, including the discovery of geological evolution with which he was familiar before his famous voyage. The author uses Grandin's struggle to overcome autistic social handicaps as a model for the necessity for everyone to create a deceptive social mask.

Readers unfamiliar with the anecdotal material Greene presents may find interesting avenues to pursue, but they should beware of the author's quirky, sometimes misleading brush-stroke characterizations.

Pub Date: Nov. 13, 2012

ISBN: 978-0-670-02496-4

Page Count: 320

Publisher: Viking

Review Posted Online: Sept. 12, 2012

Kirkus Reviews Issue: Oct. 1, 2012

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THE RIGHT STUFF

Yes: it's high time for a de-romanticized, de-mythified, close-up retelling of the U.S. Space Program's launching—the inside story of those first seven astronauts.

But no: jazzy, jivey, exclamation-pointed, italicized Tom Wolfe "Mr. Overkill" hasn't really got the fight stuff for the job. Admittedly, he covers all the ground. He begins with the competitive, macho world of test pilots from which the astronauts came (thus being grossly overqualified to just sit in a controlled capsule); he follows the choosing of the Seven, the preparations for space flight, the flights themselves, the feelings of the wives; and he presents the breathless press coverage, the sudden celebrity, the glorification. He even throws in some of the technology. But instead of replacing the heroic standard version with the ring of truth, Wolfe merely offers an alternative myth: a surreal, satiric, often cartoony Wolfe-arama that, especially since there isn't a bit of documentation along the way, has one constantly wondering if anything really happened the way Wolfe tells it. His astronauts (referred to as "the brethren" or "The True Brothers") are obsessed with having the "right stuff" that certain blend of guts and smarts that spells pilot success. The Press is a ravenous fool, always referred to as "the eternal Victorian Gent": when Walter Cronkite's voice breaks while reporting a possible astronaut death, "There was the Press the Genteel Gent, coming up with the appropriate emotion. . . live. . . with no prompting whatsoever!" And, most off-puttingly, Wolfe presumes to enter the minds of one and all: he's with near-drowing Gus Grissom ("Cox. . . That face up there!—it's Cox. . . Cox knew how to get people out of here! . . . Cox! . . ."); he's with Betty Grissom angry about not staying at Holiday Inn ("Now. . . they truly owed her"); and, in a crude hatchet-job, he's with John Glenn furious at Al Shepard's being chosen for the first flight, pontificating to the others about their licentious behavior, or holding onto his self-image during his flight ("Oh, yes! I've been here before! And I am immune! I don't get into corners I can't get out of! . . . The Presbyterian Pilot was not about to foul up. His pipeline to dear Lord could not be clearer"). Certainly there's much here that Wolfe is quite right about, much that people will be interested in hearing: the P-R whitewash of Grissom's foul-up, the Life magazine excesses, the inter-astronaut tensions. And, for those who want to give Wolfe the benefit of the doubt throughout, there are emotional reconstructions that are juicily shrill.

But most readers outside the slick urban Wolfe orbit will find credibility fatally undermined by the self-indulgent digressions, the stylistic excesses, and the broadly satiric, anti-All-American stance; and, though The Right Stuff has enough energy, sass, and dirt to attract an audience, it mostly suggests that until Wolfe can put his subject first and his preening writing-persona second, he probably won't be a convincing chronicler of anything much weightier than radical chic.

Pub Date: Sept. 24, 1979

ISBN: 0312427565

Page Count: 370

Publisher: Farrar, Straus and Giroux

Review Posted Online: Oct. 13, 2011

Kirkus Reviews Issue: Sept. 1, 1979

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