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FLU

THE STORY OF THE GREAT INFLUENZA PANDEMIC OF 1918 AND THE SEARCH FOR THE VIRUS THAT CAUSED IT

Kolata’s is a knowledgeable voice, and her enthusiasm for the chase draws us into the intrigue. Her frightening conclusion?...

A still-unsolved medical mystery, expertly told: What caused the influenza pandemic of 1918, a disaster that dwarfs every other epidemic in this century? And could it happen again?

New York Times science reporter Kolata (Clone: The Road to Dolly, 1998, etc.) was a microbiology major in college when the scope of the 1918 flu deaths first hit home for her: “It was a plague so deadly that if a similar virus were to strike today, it would kill more people in a single year than heart disease, cancers, strokes, chronic pulmonary disease, AIDS, and Alzheimer’s disease combined." In spite of the illness’s devastating toll, the origin of the 1918 flu remains a mystery. Was it a mutation in an ordinary human flu virus that caused a transformation into a global killer? Or was it a crossover from an animal disease, like the variant of swine flu that has been investigated as a possible culprit? An especially perplexing aspect of the disease is its W-shaped death curve: There were peaks for children under five years, and for the elderly ages 70 to 74 years—but also a middle peak for 20-to-40-year-olds, a surprisingly vulnerable group. Those trying to determine the mode of transmission were unable to devise any method (and Kolata relates in revolting detail a number of failed attempts) to infect healthy subjects with the disease. Throughout, she provides a number of hair-raising descriptions of the disease, which eventually afflicted more than 25 percent of the U.S. population. Along the way, readers also get a picture of the research world: At one point, many of those studying the elusive influenza viruses dropped that work to go after HIV. “Every virologist loves a new virus," confesses English scientist John Oxford, and they mistakenly thought HIV was an easy cure.

Kolata’s is a knowledgeable voice, and her enthusiasm for the chase draws us into the intrigue. Her frightening conclusion? It could happen again, at any time.

Pub Date: Nov. 18, 1999

ISBN: 0-374-15706-5

Page Count: 256

Publisher: Farrar, Straus and Giroux

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: Oct. 1, 1999

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A SHORT HISTORY OF NEARLY EVERYTHING

Loads of good explaining, with reminders, time and again, of how much remains unknown, neatly putting the death of science...

Bryson (I'm a Stranger Here Myself, 1999, etc.), a man who knows how to track down an explanation and make it confess, asks the hard questions of science—e.g., how did things get to be the way they are?—and, when possible, provides answers.

As he once went about making English intelligible, Bryson now attempts the same with the great moments of science, both the ideas themselves and their genesis, to resounding success. Piqued by his own ignorance on these matters, he’s egged on even more so by the people who’ve figured out—or think they’ve figured out—such things as what is in the center of the Earth. So he goes exploring, in the library and in company with scientists at work today, to get a grip on a range of topics from subatomic particles to cosmology. The aim is to deliver reports on these subjects in terms anyone can understand, and for the most part, it works. The most difficult is the nonintuitive material—time as part of space, say, or proteins inventing themselves spontaneously, without direction—and the quantum leaps unusual minds have made: as J.B.S. Haldane once put it, “The universe is not only queerer than we suppose; it is queerer than we can suppose.” Mostly, though, Bryson renders clear the evolution of continental drift, atomic structure, singularity, the extinction of the dinosaur, and a mighty host of other subjects in self-contained chapters that can be taken at a bite, rather than read wholesale. He delivers the human-interest angle on the scientists, and he keeps the reader laughing and willing to forge ahead, even over their heads: the human body, for instance, harboring enough energy “to explode with the force of thirty very large hydrogen bombs, assuming you knew how to liberate it and really wished to make a point.”

Loads of good explaining, with reminders, time and again, of how much remains unknown, neatly putting the death of science into perspective.

Pub Date: May 6, 2003

ISBN: 0-7679-0817-1

Page Count: 304

Publisher: Broadway

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: April 1, 2003

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LETTERS FROM AN ASTROPHYSICIST

A media-savvy scientist cleans out his desk.

Tyson (Astrophysics for People in a Hurry, 2017, etc.) receives a great deal of mail, and this slim volume collects his responses and other scraps of writing.

The prolific science commentator and bestselling author, an astrophysicist at the American Museum of Natural History, delivers few surprises and much admirable commentary. Readers may suspect that most of these letters date from the author’s earlier years when, a newly minted celebrity, he still thrilled that many of his audience were pouring out their hearts. Consequently, unlike more hardened colleagues, he sought to address their concerns. As years passed, suspecting that many had no interest in tapping his expertise or entering into an intelligent give and take, he undoubtedly made greater use of the waste basket. Tyson eschews pure fan letters, but many of these selections are full of compliments as a prelude to asking advice, pointing out mistakes, proclaiming opposing beliefs, or denouncing him. Readers will also encounter some earnest op-ed pieces and his eyewitness account of 9/11. “I consider myself emotionally strong,” he writes. “What I bore witness to, however, was especially upsetting, with indelible images of horror that will not soon leave my mind.” To crackpots, he gently repeats facts that almost everyone except crackpots accept. Those who have seen ghosts, dead relatives, and Bigfoot learn that eyewitness accounts are often unreliable. Tyson points out that extraordinary claims require extraordinary evidence, so confirmation that a light in the sky represents an alien spacecraft requires more than a photograph. Again and again he defends “science,” and his criteria—observation, repeatable experiments, honest discourse, peer review—are not controversial but will remain easy for zealots to dismiss. Among the instances of “hate mail” and “science deniers,” the author also discusses philosophy, parenting, and schooling.

A media-savvy scientist cleans out his desk.

Pub Date: Oct. 8, 2019

ISBN: 978-1-324-00331-1

Page Count: 272

Publisher: Norton

Review Posted Online: Sept. 1, 2019

Kirkus Reviews Issue: Sept. 15, 2019

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