by Gregory White Smith & Steven Naifeh ‧ RELEASE DATE: Aug. 27, 1997
What might have been simply another personal account of surviving cancer is in fact an empowering document for anyone with a life-threatening illness. Smith and Naifeh, who won a Pulitzer Prize for their biography of Jackson Pollock and together produce annual reference books on the top doctors and lawyers in the country, are bona fide experts at researching and writing. Here, Naifeh takes a back seat to Smith, who narrates this account. In 1986, aged 34, he was given three months to live by doctors at the Mayo Clinic, who told him his brain tumor was inoperable. Realizing that the statistical odds for his death still left a chance he might live, and needing to take control of his situation, Smith began a search that eventually led him to the right doctor and the right treatment. While describing that search, the authors show how the battle for control of one's life is often a struggle against both one's own feelings of denial and the intimidating, we-know-best attitude of many doctors. To illustrate that the battle can be won, they interviewed dozens of survivors of devastating accidents and illnesses—a parachutist who survived an 11,000-foot fall, a young woman who had the first double-lung transplant—as well as physicians and support group leaders around the country. Their stories, feelings, and insights give dimension to Smith's own experience. To show how the battle can be won, they offer advice on researching one's own disease, asking the right questions, developing an effective doctor-patient relationship. While they stress how essential it is to have the right attitude and how important the support of family or friends can be to winning the battle, they acknowledge that sometimes tough decisions have to be made about continuing the fight, and they argue that deciding where to draw that line is the patient's, not the doctor's, right. Persuasive evidence that ``miracles'' must be worked for—they don't just happen.
Pub Date: Aug. 27, 1997
ISBN: 0-316-59788-0
Page Count: 320
Publisher: Little, Brown
Review Posted Online: May 19, 2010
Kirkus Reviews Issue: June 1, 1997
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by David B. Agus ‧ RELEASE DATE: Jan. 7, 2014
Useful but disappointingly commonplace tips.
In a follow-up to The End of Illness (2012), which explored how technological advances will transform medicine, Agus (Medicine and Engineering/Univ. of Southern California) restates time-tested but too often overlooked principles for healthy living.
The author outlines simple measures that average citizens can take to live healthier lives and extend their life spans by taking advantage of modern technology to develop personalized records. These would include a list of medical tests and recommended treatments. Agus also suggests keeping track of indicators that can be observed at home on a regular basis—e.g., changes in energy, weight, appetite and blood pressure, blood sugar and general appearance. He advises that all of this information be made available online, and it is also helpful to investigate family history and consider DNA testing where indicated. Along with maintaining a healthy weight, Agus emphasizes the importance of eating a balanced diet, with plenty of fresh fruits and vegetables and a minimum of red meat. Avoid packaged vitamins and food supplements, and if possible, grow your own vegetables or buy frozen vegetables, which will generally be fresher than those on supermarket shelves. The author also warns against processed foods that make health claims but contain additives or excessive amounts of sugar or fat. Regular mealtimes and plenty of sleep, frequent hand-washing and oral hygiene are a must; smoking and excessive time in the sun should also be avoided. Agus recommends that adults should consider taking statins and baby aspirin as preventative measures. He concludes with a decade-by-decade checklist of annual medical examinations that should be routine—e.g. blood pressure, diabetes and cholesterol screenings, from one’s 20s on; colonoscopies, prostate exams and mammograms later—and a variety of top-10 lists (for example, “Top 10 Reasons to Take a Walk”).
Useful but disappointingly commonplace tips.Pub Date: Jan. 7, 2014
ISBN: 978-1-4767-3095-0
Page Count: 128
Publisher: Simon & Schuster
Review Posted Online: Sept. 30, 2013
Kirkus Reviews Issue: Oct. 15, 2013
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by David B. Agus ‧ RELEASE DATE: Jan. 1, 2012
Oncologist Agus (Medicine and Engineering/Univ. of Southern California) predicts that the application of advanced technology for modeling complex systems will transform 21st-century medicine.
The author writes that a remark Nobel Laureate Murray Gell-Mann made to him in 2009—“Look at cancer as a system"—transformed the way he views his own specialty and the entire field of preventative medicine. It made him realize that “[r]ather than honoring the body as the exceedingly complex system that it is, we keep looking for the individual gene that has gone awry, or for the one ‘secret’ that can improve our health.” Agus writes that although the ability to sequence the entire human genome is a great step forward, it is insufficient for achieving a significant breakthrough. Even though it may start with a mutation, cancer “is a dynamic process that's happening…far from the confines of a static piece of DNA”—it involves the body's immune system, its ability to regulate cell growth, metabolism and more. Agus directs his university’s Center for Applied Molecular Medicine and is the co-founder of two personalized medicine companies, Applied Proteomics and Navigenics. His hope is that their research will contribute to developing better analytical tools for preventative medicine and for the treatment of cancers. These will address the functioning of the body as a whole, applying digital technology already used by physicists to provide virtual models of cancers and model the action of proteins that regulate cell communication in the body. He also hopes to develop tools that will provide information on the concentration of different proteins in a drop of blood taken from a patient, which may reveal the onset of disease. The author also includes some guiding principles and warnings about certain healthy practices that may not be so healthy. A refreshing change of pace in the medical field, but by venturing beyond his field of expertise to pontificate on a wide range of subjects, Agus makes his otherwise intriguing narrative difficult to follow.
Pub Date: Jan. 1, 2012
ISBN: 978-1-4516-1017-8
Page Count: 288
Publisher: Free Press
Review Posted Online: Nov. 5, 2011
Kirkus Reviews Issue: Nov. 15, 2011
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