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POISONED

THE TRUE STORY OF THE DEADLY E. COLI OUTBREAK THAT CHANGED THE WAY AMERICANS EAT

Just in time for BBQ season, an investigative journalist traces the path of a devastating outbreak of food-borne illness linked to hamburger meat.

In 1993, nobody, save for a lab technician or two, knew anything about a dangerous strain of bacteria called E. Coli, which has the potential to cause illness and death. With careful attention to detail, Benedict (Little Pink House: A True Story of Defiance and Courage, 2009, etc.), illustrates the danger in this thorough exploration of the Jack in the Box E. Coli outbreak that killed four children and sickened 700 more in several states. The author, who holds a law degree, fashions the book like a police procedural, keeping the beat with quick cuts to the major players—parents waiting by their dying children's bedsides, lawyers and corporate executives. With accounts of his firsthand interviews and observation, Benedict provides a powerful reminder that food safety is a matter of life and death, as in the case of Suzanne Kiner and her daughter Brianne: “Desperate, she turned to a few vials of holy water that had been given to her by women of faith-complete strangers. Suzanne often wondered whether the stuff had any real power...Looking around and seeing no nurses in sight, Suzanne removed the tops of the vials and poured the contents all over Brianne's head. She even put a few drops in Brianne's IV. This is it, she thought. I can't beg any more time for her.” Spartan prose delivers a chilling, page-turning lesson in food safety.

 

Pub Date: May 17, 2011

ISBN: 978-0-9833478-0-4

Page Count: 314

Publisher: Inspire Books

Review Posted Online: May 3, 2011

Kirkus Reviews Issue: May 15, 2011

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A SHORT GUIDE TO A LONG LIFE

Useful but disappointingly commonplace tips.

In a follow-up to The End of Illness (2012), which explored how technological advances will transform medicine, Agus (Medicine and Engineering/Univ. of Southern California) restates time-tested but too often overlooked principles for healthy living.

The author outlines simple measures that average citizens can take to live healthier lives and extend their life spans by taking advantage of modern technology to develop personalized records. These would include a list of medical tests and recommended treatments. Agus also suggests keeping track of indicators that can be observed at home on a regular basis—e.g., changes in energy, weight, appetite and blood pressure, blood sugar and general appearance. He advises that all of this information be made available online, and it is also helpful to investigate family history and consider DNA testing where indicated. Along with maintaining a healthy weight, Agus emphasizes the importance of eating a balanced diet, with plenty of fresh fruits and vegetables and a minimum of red meat. Avoid packaged vitamins and food supplements, and if possible, grow your own vegetables or buy frozen vegetables, which will generally be fresher than those on supermarket shelves. The author also warns against processed foods that make health claims but contain additives or excessive amounts of sugar or fat. Regular mealtimes and plenty of sleep, frequent hand-washing and oral hygiene are a must; smoking and excessive time in the sun should also be avoided. Agus recommends that adults should consider taking statins and baby aspirin as preventative measures. He concludes with a decade-by-decade checklist of annual medical examinations that should be routine—e.g. blood pressure, diabetes and cholesterol screenings, from one’s 20s on; colonoscopies, prostate exams and mammograms later—and a variety of top-10 lists (for example, “Top 10 Reasons to Take a Walk”).

Useful but disappointingly commonplace tips.

Pub Date: Jan. 7, 2014

ISBN: 978-1-4767-3095-0

Page Count: 128

Publisher: Simon & Schuster

Review Posted Online: Sept. 30, 2013

Kirkus Reviews Issue: Oct. 15, 2013

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THE END OF ILLNESS

Oncologist Agus (Medicine and Engineering/Univ. of Southern California) predicts that the application of advanced technology for modeling complex systems will transform 21st-century medicine.

The author writes that a remark Nobel Laureate Murray Gell-Mann made to him in 2009—“Look at cancer as a system"—transformed the way he views his own specialty and the entire field of preventative medicine. It made him realize that “[r]ather than honoring the body as the exceedingly complex system that it is, we keep looking for the individual gene that has gone awry, or for the one ‘secret’ that can improve our health.” Agus writes that although the ability to sequence the entire human genome is a great step forward, it is insufficient for achieving a significant breakthrough. Even though it may start with a mutation, cancer “is a dynamic process that's happening…far from the confines of a static piece of DNA”—it involves the body's immune system, its ability to regulate cell growth, metabolism and more. Agus directs his university’s Center for Applied Molecular Medicine and is the co-founder of two personalized medicine companies, Applied Proteomics and Navigenics. His hope is that their research will contribute to developing better analytical tools for preventative medicine and for the treatment of cancers. These will address the functioning of the body as a whole, applying digital technology already used by physicists to provide virtual models of cancers and model the action of proteins that regulate cell communication in the body. He also hopes to develop tools that will provide information on the concentration of different proteins in a drop of blood taken from a patient, which may reveal the onset of disease. The author also includes some guiding principles and warnings about certain healthy practices that may not be so healthy. A refreshing change of pace in the medical field, but by venturing beyond his field of expertise to pontificate on a wide range of subjects, Agus makes his otherwise intriguing narrative difficult to follow.  

 

Pub Date: Jan. 1, 2012

ISBN: 978-1-4516-1017-8

Page Count: 288

Publisher: Free Press

Review Posted Online: Nov. 5, 2011

Kirkus Reviews Issue: Nov. 15, 2011

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