Erudite essays that explore the pros and cons of reductionism in science. There have been rumblings in the halls of academe that reductionism—in which the whole is explained by a dissection of its parts—will not remain the dominant mode of doing science. Biologists speak of the need for ``integrative biology''; medicine has its adherents of ``holistic'' approaches. To explore the issue, Cornwell, director of the Science and Human Dimension Project at Jesus College, Cambridge University, assembled a stellar cast of scientists and philosophers for a 1992 symposium. Physicist Freeman Dyson leads off with an essay describing scientists as artists striving against a given culture; he also stumps for multiple visions rather than a single vision of science. There follow a number of essays describing how the turn-of-the-century vision to reduce all of mathematics to a few pure axioms was blown out of the water by the intricate theorems of Kurt GĂ®del. Astronomer John Barrow casts doubt on theories of everything and the concept that the universe is a continuum, while Roger Penrose states themes that are later repeated in a series of essays on neuroscience and artificial intelligence. These have to do with whether mind equals brain, whether the brain is a computer, and what is meant by computability. There is steep sledding with Nobelist Gerald Edelman and colleague Giolio Tononi's exposition of the theory of neuronal group selection—steep enough to require a following explanatory essay by none other than Oliver Sacks. The upshot is that, with the exception of a couple of spirited voices championing reductionism, the authors declare, ``The king is dead, long live the replacement''—which Edelman, in a concluding essay far more pithy than his first, describes as a ``second'' enlightenment that can celebrate human freedom. Some nuggets here for philosophers of science, neuroscientists, mathematicians, and computer folks—but one wonders if maybe Cornwell didn't stack the deck a bit and if a different cast might have come up with a different consensus.