THE TERMINAL GENE

A geneticist uncovers a universal, hardwired gene that determines the moment of one’s death in Thomas’ SF novel.

In the high-tech hub of Boston, Helix Innovations is a cutting-edge biomedical giant researching the predictive genetic foundations of dire maladies. One of their young shining-star scientists, Dr. Emily Harper (who has a background in computer hacking), makes a shocking discovery: the “terminal gene,” sometimes called a “kill switch.” It seems every living organism possesses this, a predetermined biological timer that unerringly forecasts exactly when that living thing will die. Such powerful knowledge applied by unscrupulous business interests and authorities is a frightening prospect: “The terminal gene had the potential to redefine medicine, providing insights into deadly diseases, or it might disrupt society, giving governments and corporations the power to exploit mortality...Would the government weaponize it, sorting citizens by their expiration dates?” Straightaway, Emily begins to receive threatening messages warning her to keep quiet and cooperate, or else. The danger seems to originate from a secret group called Chronos, which is already setting itself up to control the terminal gene and actively scheming to find a way to “reset” it. A mysterious person (or persons) known only as “Q” is also involved, though whether they are friend or foe is unknown. Emily’s apartment is ransacked, and the young scientist finds herself locked out of security protocols. This is too much for Emily’s live-in fiancé, Tyler, an ex-soldier with dormant-but-deadly combat skills. He and Emily zero in on unfriendly Helix CEO James Kessler as a likely source of harassment. But as paranoia escalates, it seems nobody can be trusted—not cherished academic mentors, Tyler’s former military associates, or a mysteriously reappearing Boston beat cop. Even worse, carefully concealed terminal-gene data indicates the approach of a mass-extinction event.

Some readers may find the terminal-gene concept to be less like a plot device from one of Michael Crichton’s just-on-the-edge-of-plausible thrillers and more like something bubbled up from the surrealistic imagination of Jorge Luis Borges (or early-1950s horror comic books). The concept is rather akin to a pin-cushioned Voodoo doll or a monkey’s paw that dictates one’s fate paranormally (death will come, no matter what ones does to prepare for or prevent it) rather than scientifically, though quite late in the action is there is some doubletalk about retroviruses and the like. Curiously, the story remains Boston-centric, even as news spreads of the doomsday discovery—the reactions from Washington, D.C., Wall Street, and the world in general feel curiously marginal. Readers able to suspend their disbelief will be left with an agreeable beach (or possibly hospital ward) read. It is only in the home stretch that the author addresses the philosophical conundrum, “Is it possible to reconcile human free will with a universe ruled by deterministic laws of nature?” before getting back to the action-heavy business of skulking through intranet firewalls and sneaking into besieged CRISPR labs (it is amusing how Emily, a celebrity whistleblower, can go unnoticed in a Beantown roiled by anti-Helix protests). One need not be a geneticist to diagnose the likelihood of sequels germinating.

A far-fetched but often fun SF thriller.