Pages tightened with hospital corners, the changing of the guard merely changes the sheets of one generation of country doctors to the next, and what a dismal business it is. Death caused by a Negro abortionist (a lecher) is ""to die a woman's worst death"", but an operation to correct a girl's strabismus is sufficiently ennobling for the boy hero to make him swear in as a dedicated doctor. When Guy and Claire's parents lose all in the Great Crash of '29, they also meet a sudden death. Was it suicide? No matter- Guy and Claire are hustled off to live with their aunt and uncle. Well, shades of Red Lewis (Sinclair), they are living in Omega (Zenith? Zenith?) and Guy becomes another Arrowsmith in corn huskin's. Under the tutelage of Doc Remington, the old guard, he learns why his mother couldn't have committed suicide, and he is indoctrinated as a diagnostician. Eventually he achieves the hospital of his dreams, right there in Omega.... The sentiments are all heart- forwardly straightwarming, but the material is pretty shoddy.