Impressive research and good storytelling. (Maps, 16 pages b&w illustrations, not seen)
An absorbing chronicle of two related adventures: the 19th-century hunt by botanical explorers in the Andes for the cinchona tree, whose bark produces quinine, once the only effective treatment for malaria; and the contemporary quest by scientists in the laboratory to find a cure for this deadly disease.
British journalist Honigsbaum focuses on the stories of three men: Richard Spruce, a botanist who spent 15 years in the Amazon and Andes; Charles Ledger, a trader who made numerous expeditions through Peru, Bolivia, and Chile; and Sir Clements Markham, a historian attached to the India Office who coordinated several cinchona-seeking forays to South America in the 1860s. With malaria rampant in India and Africa, the British were desperate to secure a source of quinine. Their plan was to take cinchona seeds from South America and start cinchona plantations in India. Harsh geography, fearsome insects, head-hunting Indians, and political unrest made finding the seeds extraordinarily hazardous, and growing the trees in India posed an unexpectedly complex horticultural challenge. As matters worked out, the best seeds ended up in the hands of Dutch plantation owners in Java, which by 1937 supplied 97% of the world’s quinine. Honigsbaum, who traveled to South America to research the cinchona adventure, devotes most of his text to it, turning to the scientific search for a malaria cure only in the last three chapters. There, after a compressed but informative history, he considers the issues of increasing drug resistance, the resurgence of tropical diseases such as malaria because of global warming, the reluctance of profit-conscious pharmaceutical manufacturers to devote large sums of money to malaria research, and the problems facing the ongoing hunt for a vaccine.
Impressive research and good storytelling. (Maps, 16 pages b&w illustrations, not seen)Pub Date: May 1, 2001
ISBN: 0-374-15469-4
Page Count: 368
Publisher: Farrar, Straus and Giroux
Review Posted Online: May 19, 2010
Kirkus Reviews Issue: March 1, 2002
BOOK REVIEW
BOOK REVIEW
An intriguing meditation on the nature of the universe and our attempts to understand it that should appeal to both...
Italian theoretical physicist Rovelli (General Relativity: The Most Beautiful of Theories, 2015, etc.) shares his thoughts on the broader scientific and philosophical implications of the great revolution that has taken place over the past century.
These seven lessons, which first appeared as articles in the Sunday supplement of the Italian newspaper Sole 24 Ore, are addressed to readers with little knowledge of physics. In less than 100 pages, the author, who teaches physics in both France and the United States, cogently covers the great accomplishments of the past and the open questions still baffling physicists today. In the first lesson, he focuses on Einstein's theory of general relativity. He describes Einstein's recognition that gravity "is not diffused through space [but] is that space itself" as "a stroke of pure genius." In the second lesson, Rovelli deals with the puzzling features of quantum physics that challenge our picture of reality. In the remaining sections, the author introduces the constant fluctuations of atoms, the granular nature of space, and more. "It is hardly surprising that there are more things in heaven and earth, dear reader, than have been dreamed of in our philosophy—or in our physics,” he writes. Rovelli also discusses the issues raised in loop quantum gravity, a theory that he co-developed. These issues lead to his extraordinary claim that the passage of time is not fundamental but rather derived from the granular nature of space. The author suggests that there have been two separate pathways throughout human history: mythology and the accumulation of knowledge through observation. He believes that scientists today share the same curiosity about nature exhibited by early man.
An intriguing meditation on the nature of the universe and our attempts to understand it that should appeal to both scientists and general readers.Pub Date: March 1, 2016
ISBN: 978-0-399-18441-3
Page Count: 96
Publisher: Riverhead
Review Posted Online: Dec. 7, 2015
Kirkus Reviews Issue: Dec. 15, 2015
BOOK REVIEW
BOOK REVIEW
A magnificent account of a central reality of our times, incorporating deep scientific expertise, broad political and social knowledge, and ethical insight, and Idled with beautifully written biographical sketches of the men and women who created nuclear physics. Rhodes describes in detail the great scientific achievements that led up to the invention of the atomic bomb. Everything of importance is examined, from the discovery of the atomic nucleus and of nuclear fission to the emergence of quantum physics, the invention of the mass-spectroscope and of the cyclotron, the creation of such man-made elements as plutonium and tritium, and implementation of the nuclear chain reaction in uranium. Even more important, Rhodes shows how these achievements were thrust into the arms of the state, which culminated in the unfolding of the nuclear arms race. Often brilliantly, he records the rise of fascism and of anti-Semitism, and the intensification of nationalist ambitions. He traces the outbreak of WW II, which provoked a hysterical rivalry among nations to devise the bomb. This book contains a grim description of Japanese resistance, and of the horrible psychological numbing that caused an unparalleled tolerance for human suffering and destruction. Rhodes depicts the Faustian scale of the Manhattan Project. His account of the dropping of the bomb itself, and of the awful firebombing that prepared its way, is unforgettable. Although Rhodes' gallery of names and events is sometimes dizzying, his scientific discussions often daunting, he has written a book of great drama and sweep. A superb accomplishment.
Pub Date: Feb. 1, 1986
ISBN: 0684813785
Page Count: 932
Publisher: Simon & Schuster
Review Posted Online: Oct. 28, 2011
Kirkus Reviews Issue: Jan. 15, 1986
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