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AGAINST DEPRESSION

A clear, valuable exposition of the progress researchers are making in understanding an all-too-common disease.

A heartfelt argument that depression is not, as many would have it, a source of heroic melancholy and artistic genius, but, rather, a pathological condition that should, if possible, be eradicated.

When Kramer (Clinical Psychiatry/Brown Univ.) made public appearances after publication of his best-selling Listening to Prozac (1993), audiences persistently challenged him with questions like, “What if Prozac had been available in van Gogh’s time?” The assumption that suffering from mental illness is a prerequisite to genius and that humanity would be the poorer if depression were conquered is anathema to Kramer. Instead, he asserts, it is “the most devastating disease known to humankind,” and to back up his claim he cites some astonishing statistics: $40 billion in lost productivity in the United States, for example, or 3 percent of GDP. In a wide-ranging essay that draws on his own life and on his years of treating patients, he explores the gap between common perceptions of depression and the scientific understanding of it. In the first of three parts here, “What It Is to Us,” he looks at the charm of depression and its erotic power, at the way people are drawn to such precursors of depression as moodiness, passivity and vulnerability. In “What It Is,” he reviews research in biological psychiatry and neuroscience that links depression to frank abnormalities in the nervous system, including problems in stress responses, repair of cells in critical brain regions, and small or malfunctioning hippocampus glands. Finally, in “What It Will Be,” Kramer envisions a world without depression and lists benefits of its eradication. Without depression to fear, he says, we would be free to be quirky and neurotic, to take risks more openly and to love more generously—and we’d still have art and artists. While not predicting that depression will be eliminated anytime soon, Kramer brings hope to those afflicted by it.

A clear, valuable exposition of the progress researchers are making in understanding an all-too-common disease.

Pub Date: May 9, 2005

ISBN: 0-670-03405-3

Page Count: 340

Publisher: Viking

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: March 1, 2005

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MASTERY

Readers unfamiliar with the anecdotal material Greene presents may find interesting avenues to pursue, but they should...

Greene (The 33 Strategies of War, 2007, etc.) believes that genius can be learned if we pay attention and reject social conformity.

The author suggests that our emergence as a species with stereoscopic, frontal vision and sophisticated hand-eye coordination gave us an advantage over earlier humans and primates because it allowed us to contemplate a situation and ponder alternatives for action. This, along with the advantages conferred by mirror neurons, which allow us to intuit what others may be thinking, contributed to our ability to learn, pass on inventions to future generations and improve our problem-solving ability. Throughout most of human history, we were hunter-gatherers, and our brains are engineered accordingly. The author has a jaundiced view of our modern technological society, which, he writes, encourages quick, rash judgments. We fail to spend the time needed to develop thorough mastery of a subject. Greene writes that every human is “born unique,” with specific potential that we can develop if we listen to our inner voice. He offers many interesting but tendentious examples to illustrate his theory, including Einstein, Darwin, Mozart and Temple Grandin. In the case of Darwin, Greene ignores the formative intellectual influences that shaped his thought, including the discovery of geological evolution with which he was familiar before his famous voyage. The author uses Grandin's struggle to overcome autistic social handicaps as a model for the necessity for everyone to create a deceptive social mask.

Readers unfamiliar with the anecdotal material Greene presents may find interesting avenues to pursue, but they should beware of the author's quirky, sometimes misleading brush-stroke characterizations.

Pub Date: Nov. 13, 2012

ISBN: 978-0-670-02496-4

Page Count: 320

Publisher: Viking

Review Posted Online: Sept. 12, 2012

Kirkus Reviews Issue: Oct. 1, 2012

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THINKING, FAST AND SLOW

Striking research showing the immense complexity of ordinary thought and revealing the identities of the gatekeepers in our...

A psychologist and Nobel Prize winner summarizes and synthesizes the recent decades of research on intuition and systematic thinking.

The author of several scholarly texts, Kahneman (Emeritus Psychology and Public Affairs/Princeton Univ.) now offers general readers not just the findings of psychological research but also a better understanding of how research questions arise and how scholars systematically frame and answer them. He begins with the distinction between System 1 and System 2 mental operations, the former referring to quick, automatic thought, the latter to more effortful, overt thinking. We rely heavily, writes, on System 1, resorting to the higher-energy System 2 only when we need or want to. Kahneman continually refers to System 2 as “lazy”: We don’t want to think rigorously about something. The author then explores the nuances of our two-system minds, showing how they perform in various situations. Psychological experiments have repeatedly revealed that our intuitions are generally wrong, that our assessments are based on biases and that our System 1 hates doubt and despises ambiguity. Kahneman largely avoids jargon; when he does use some (“heuristics,” for example), he argues that such terms really ought to join our everyday vocabulary. He reviews many fundamental concepts in psychology and statistics (regression to the mean, the narrative fallacy, the optimistic bias), showing how they relate to his overall concerns about how we think and why we make the decisions that we do. Some of the later chapters (dealing with risk-taking and statistics and probabilities) are denser than others (some readers may resent such demands on System 2!), but the passages that deal with the economic and political implications of the research are gripping.

Striking research showing the immense complexity of ordinary thought and revealing the identities of the gatekeepers in our minds.

Pub Date: Nov. 1, 2011

ISBN: 978-0-374-27563-1

Page Count: 512

Publisher: Farrar, Straus and Giroux

Review Posted Online: Sept. 3, 2011

Kirkus Reviews Issue: Sept. 15, 2011

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