A meticulous and thoughtful scientific exploration.
A thorough tour of the science of depression, including its causes and its treatment.
Motivated to understand the suicidal depression that plagued a close friend, debut author Zabel, a retired major general in the U.S. Air Force, delved deeply into the constantly evolving research, hoping to find answers. The result is this remarkably comprehensive assessment of the competing theories regarding the reasons for depression, and of its therapeutic treatment. The author lucidly chronicles the shifting expert consensus on depression, from its interpretation as a trauma response to its acknowledgement as a biologically based illness. The candidate causes, however, are many. Is it the result of a chemical deficiency, or an excess of inflammation, or is it a function of cellular energy metabolism? One promising theory, the author notes, views depression as a stultification of neuroplasticity; a brain is in the continuous throes of “abrasion” and repair, and depression may result when the effects of the former surpass the latter’s. Zabel’s study is breathtakingly expansive—she looks at epidemiological surveys of a range of demographics, and provides a rigorous but accessible synopsis of the brain’s general functioning. The book is a combination of highly technical research and anecdotal accounts, as the author interviews many sufferers of depression, endowing the work with a sensitively handled human element. There are times when a lay reader may feel overwhelmed by the large amount of minute detail. However, Zabel never strays too far from the big picture and resists the allure of facile answers: “At my core, I am reductionist—I want to find the simple solution, the fundamental biological problem that is depression...but depression doesn’t support that. It is hugely complex; an emergent outcome of a brain under attack.”
A meticulous and thoughtful scientific exploration.Pub Date: Feb. 1, 2021
ISBN: 978-1-73584-540-1
Page Count: 432
Publisher: Sarah Zabel Enterprises, LLC
Review Posted Online: March 17, 2021
Review Program: Kirkus Indie
Sedaris at his darkest—and his best.
In which the veteran humorist enters middle age with fine snark but some trepidation as well.
Mortality is weighing on Sedaris (Theft by Finding: Diaries 1977-2002, 2017, etc.), much of it his own, professional narcissist that he is. Watching an elderly man have a bowel accident on a plane, he dreaded the day when he would be the target of teenagers’ jokes “as they raise their phones to take my picture from behind.” A skin tumor troubled him, but so did the doctor who told him he couldn’t keep it once it was removed. “But it’s my tumor,” he insisted. “I made it.” (Eventually, he found a semitrained doctor to remove and give him the lipoma, which he proceeded to feed to a turtle.) The deaths of others are much on the author’s mind as well: He contemplates the suicide of his sister Tiffany, his alcoholic mother’s death, and his cantankerous father’s erratic behavior. His contemplation of his mother’s drinking—and his family’s denial of it—makes for some of the most poignant writing in the book: The sound of her putting ice in a rocks glass increasingly sounded “like a trigger being cocked.” Despite the gloom, however, frivolity still abides in the Sedaris clan. His summer home on the Carolina coast, which he dubbed the Sea Section, overspills with irreverent bantering between him and his siblings as his long-suffering partner, Hugh, looks on. Sedaris hasn’t lost his capacity for bemused observations of the people he encounters. For example, cashiers who say “have a blessed day” make him feel “like you’ve been sprayed against your will with God cologne.” But bad news has sharpened the author’s humor, and this book is defined by a persistent, engaging bafflement over how seriously or unseriously to take life when it’s increasingly filled with Trump and funerals.
Sedaris at his darkest—and his best.Pub Date: May 29, 2018
ISBN: 978-0-316-39238-9
Page Count: 288
Publisher: Little, Brown
Review Posted Online: Feb. 19, 2018
Kirkus Reviews Issue: March 1, 2018
PROFILES
These are not hard and fast rules, but Meyer delivers important reading for those engaged in international business.
A helpful guide to working effectively with people from other cultures.
“The sad truth is that the vast majority of managers who conduct business internationally have little understanding about how culture is impacting their work,” writes Meyer, a professor at INSEAD, an international business school. Yet they face a wider array of work styles than ever before in dealing with clients, suppliers and colleagues from around the world. When is it best to speak or stay quiet? What is the role of the leader in the room? When working with foreign business people, failing to take cultural differences into account can lead to frustration, misunderstanding or worse. Based on research and her experiences teaching cross-cultural behaviors to executive students, the author examines a handful of key areas. Among others, they include communicating (Anglo-Saxons are explicit; Asians communicate implicitly, requiring listeners to read between the lines), developing a sense of trust (Brazilians do it over long lunches), and decision-making (Germans rely on consensus, Americans on one decider). In each area, the author provides a “culture map scale” that positions behaviors in more than 20 countries along a continuum, allowing readers to anticipate the preferences of individuals from a particular country: Do they like direct or indirect negative feedback? Are they rigid or flexible regarding deadlines? Do they favor verbal or written commitments? And so on. Meyer discusses managers who have faced perplexing situations, such as knowledgeable team members who fail to speak up in meetings or Indians who offer a puzzling half-shake, half-nod of the head. Cultural differences—not personality quirks—are the motivating factors behind many behavioral styles. Depending on our cultures, we understand the world in a particular way, find certain arguments persuasive or lacking merit, and consider some ways of making decisions or measuring time natural and others quite strange.
These are not hard and fast rules, but Meyer delivers important reading for those engaged in international business.Pub Date: May 27, 2014
ISBN: 978-1-61039-250-1
Page Count: 288
Publisher: PublicAffairs
Review Posted Online: April 15, 2014
Kirkus Reviews Issue: May 1, 2014
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