Armstrong’s sensible review of anti-aging science concludes that its goal is achievable—but not yet.
An exploration of aging that answers all readers’ questions except how they might reverse it.
Innumerable enthusiastic authors have revealed how to achieve vast longevity, but British science writer Armstrong (P53: The Gene that Cracked the Cancer Code, 2015) confines herself to genuine aging research, the scientists who engage in it, and the problems they face. It turns out that the news is not all bad. Early theorists pointed out that germ cells (ova and sperm) are immortal; every other body cell (the soma) supports them. Once the organism has reproduced, somatic cells have served their purpose, so evolution removes them to make room for a new generation. “Just because aging is a natural process that happens to us all inexorably…it doesn’t mean that it is either healthy or intractable,” writes Armstrong, who emphasizes that aging seems wasteful. After all, evolution designed a complex process to build an adult from a tiny embryo, but then it falls apart. Wouldn’t it be easier to keep it working than to build it in the first place? Scientists have discovered many mechanisms of aging whose fashions wax and wane. Perhaps harmful genetic mutations gradually accumulate. Perhaps free radicals, chemical products of metabolism, slowly oxidize our defenses. This remains debatable among scientists, but “antioxidants” have become a bestselling health product. Another preoccupation is the telomere, a cap on every chromosome that shortens with each cell division. Once the telomere becomes too short, the cell stops dividing and enters senescence. Keeping it long may be the solution—or maybe not. Stopping the immune system’s steady decline with age seems a possibility. Other researchers hope to tap our body’s immature stem cells. These retain the ability to mature into every kind of tissue, so this would permit creation of fresh young replacement organs.
Armstrong’s sensible review of anti-aging science concludes that its goal is achievable—but not yet.Pub Date: Feb. 26, 2019
ISBN: 978-1-4729-3606-6
Page Count: 272
Publisher: Bloomsbury Sigma
Review Posted Online: Nov. 25, 2018
Kirkus Reviews Issue: Dec. 15, 2018
BOOK REVIEW
An intriguing meditation on the nature of the universe and our attempts to understand it that should appeal to both...
Italian theoretical physicist Rovelli (General Relativity: The Most Beautiful of Theories, 2015, etc.) shares his thoughts on the broader scientific and philosophical implications of the great revolution that has taken place over the past century.
These seven lessons, which first appeared as articles in the Sunday supplement of the Italian newspaper Sole 24 Ore, are addressed to readers with little knowledge of physics. In less than 100 pages, the author, who teaches physics in both France and the United States, cogently covers the great accomplishments of the past and the open questions still baffling physicists today. In the first lesson, he focuses on Einstein's theory of general relativity. He describes Einstein's recognition that gravity "is not diffused through space [but] is that space itself" as "a stroke of pure genius." In the second lesson, Rovelli deals with the puzzling features of quantum physics that challenge our picture of reality. In the remaining sections, the author introduces the constant fluctuations of atoms, the granular nature of space, and more. "It is hardly surprising that there are more things in heaven and earth, dear reader, than have been dreamed of in our philosophy—or in our physics,” he writes. Rovelli also discusses the issues raised in loop quantum gravity, a theory that he co-developed. These issues lead to his extraordinary claim that the passage of time is not fundamental but rather derived from the granular nature of space. The author suggests that there have been two separate pathways throughout human history: mythology and the accumulation of knowledge through observation. He believes that scientists today share the same curiosity about nature exhibited by early man.
An intriguing meditation on the nature of the universe and our attempts to understand it that should appeal to both scientists and general readers.Pub Date: March 1, 2016
ISBN: 978-0-399-18441-3
Page Count: 96
Publisher: Riverhead
Review Posted Online: Dec. 7, 2015
Kirkus Reviews Issue: Dec. 15, 2015
BOOK REVIEW
BOOK REVIEW
A magnificent account of a central reality of our times, incorporating deep scientific expertise, broad political and social knowledge, and ethical insight, and Idled with beautifully written biographical sketches of the men and women who created nuclear physics. Rhodes describes in detail the great scientific achievements that led up to the invention of the atomic bomb. Everything of importance is examined, from the discovery of the atomic nucleus and of nuclear fission to the emergence of quantum physics, the invention of the mass-spectroscope and of the cyclotron, the creation of such man-made elements as plutonium and tritium, and implementation of the nuclear chain reaction in uranium. Even more important, Rhodes shows how these achievements were thrust into the arms of the state, which culminated in the unfolding of the nuclear arms race. Often brilliantly, he records the rise of fascism and of anti-Semitism, and the intensification of nationalist ambitions. He traces the outbreak of WW II, which provoked a hysterical rivalry among nations to devise the bomb. This book contains a grim description of Japanese resistance, and of the horrible psychological numbing that caused an unparalleled tolerance for human suffering and destruction. Rhodes depicts the Faustian scale of the Manhattan Project. His account of the dropping of the bomb itself, and of the awful firebombing that prepared its way, is unforgettable. Although Rhodes' gallery of names and events is sometimes dizzying, his scientific discussions often daunting, he has written a book of great drama and sweep. A superb accomplishment.
Pub Date: Feb. 1, 1986
ISBN: 0684813785
Page Count: 932
Publisher: Simon & Schuster
Review Posted Online: Oct. 28, 2011
Kirkus Reviews Issue: Jan. 15, 1986
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