A stirring account of how important scientific research gets done.
Former Los Angeles Times national reporter McDermott (Perfect Soldiers: The 9/11 Hijackers: Who They Were, Why They Did It, 2006) tells the story of the driven neuroscientist Gary Lynch and his ongoing quest to discover the biochemical workings of memory.
Scientists have long been searching for the explanation of how memories are produced in the human brain and how they are stored and recalled. As McDermott explains in 101 Theory Drive—named after the street address of Lynch’s lab—Lynch has obsessively been trying to answer those complex questions for decades. With a chemist, he has also been working on drugs called ampakines, which could theoretically help improve memory function and restore the brain’s cognitive abilities—a potential boon for sufferers of Alzheimer’s and other neurological diseases. Starting in late 2004, McDermott spent nearly two years observing the work in the scientist’s lab. He chronicles the progress of Lynch’s research and provides an engaging portrait of the colorful but not-always-likable Lynch. The author ably explains highly technical concepts of neurology and breaks down complicated ideas in ways that general readers can easily understand. He’s equally at home describing the obsessive Lynch, who is portrayed as ambitious, brilliant and conversant on a dizzying array of subjects, but also impatient, full of self-regard and tough on his staff. The book opens with Lynch alone in his lab, annoyed that the rest of his team dared take a break between Christmas and New Year’s Day. McDermott also pays attention to key members of Lynch’s staff, such as neurophysiologist Eniko Kramar, whose workaholic devotion to Lynch’s work is described by her friends as “just short of self-destructive.”
A stirring account of how important scientific research gets done.Pub Date: April 6, 2010
ISBN: 978-0-375-42538-7
Page Count: 288
Publisher: Pantheon
Review Posted Online: Jan. 19, 2011
Kirkus Reviews Issue: Jan. 1, 2010
Readers unfamiliar with the anecdotal material Greene presents may find interesting avenues to pursue, but they should...
Greene (The 33 Strategies of War, 2007, etc.) believes that genius can be learned if we pay attention and reject social conformity.
The author suggests that our emergence as a species with stereoscopic, frontal vision and sophisticated hand-eye coordination gave us an advantage over earlier humans and primates because it allowed us to contemplate a situation and ponder alternatives for action. This, along with the advantages conferred by mirror neurons, which allow us to intuit what others may be thinking, contributed to our ability to learn, pass on inventions to future generations and improve our problem-solving ability. Throughout most of human history, we were hunter-gatherers, and our brains are engineered accordingly. The author has a jaundiced view of our modern technological society, which, he writes, encourages quick, rash judgments. We fail to spend the time needed to develop thorough mastery of a subject. Greene writes that every human is “born unique,” with specific potential that we can develop if we listen to our inner voice. He offers many interesting but tendentious examples to illustrate his theory, including Einstein, Darwin, Mozart and Temple Grandin. In the case of Darwin, Greene ignores the formative intellectual influences that shaped his thought, including the discovery of geological evolution with which he was familiar before his famous voyage. The author uses Grandin's struggle to overcome autistic social handicaps as a model for the necessity for everyone to create a deceptive social mask.
Readers unfamiliar with the anecdotal material Greene presents may find interesting avenues to pursue, but they should beware of the author's quirky, sometimes misleading brush-stroke characterizations.Pub Date: Nov. 13, 2012
ISBN: 978-0-670-02496-4
Page Count: 320
Publisher: Viking
Review Posted Online: Sept. 12, 2012
Kirkus Reviews Issue: Oct. 1, 2012
BOOK REVIEW
BOOK REVIEW
Striking research showing the immense complexity of ordinary thought and revealing the identities of the gatekeepers in our...
A psychologist and Nobel Prize winner summarizes and synthesizes the recent decades of research on intuition and systematic thinking.
The author of several scholarly texts, Kahneman (Emeritus Psychology and Public Affairs/Princeton Univ.) now offers general readers not just the findings of psychological research but also a better understanding of how research questions arise and how scholars systematically frame and answer them. He begins with the distinction between System 1 and System 2 mental operations, the former referring to quick, automatic thought, the latter to more effortful, overt thinking. We rely heavily, writes, on System 1, resorting to the higher-energy System 2 only when we need or want to. Kahneman continually refers to System 2 as “lazy”: We don’t want to think rigorously about something. The author then explores the nuances of our two-system minds, showing how they perform in various situations. Psychological experiments have repeatedly revealed that our intuitions are generally wrong, that our assessments are based on biases and that our System 1 hates doubt and despises ambiguity. Kahneman largely avoids jargon; when he does use some (“heuristics,” for example), he argues that such terms really ought to join our everyday vocabulary. He reviews many fundamental concepts in psychology and statistics (regression to the mean, the narrative fallacy, the optimistic bias), showing how they relate to his overall concerns about how we think and why we make the decisions that we do. Some of the later chapters (dealing with risk-taking and statistics and probabilities) are denser than others (some readers may resent such demands on System 2!), but the passages that deal with the economic and political implications of the research are gripping.
Striking research showing the immense complexity of ordinary thought and revealing the identities of the gatekeepers in our minds.Pub Date: Nov. 1, 2011
ISBN: 978-0-374-27563-1
Page Count: 512
Publisher: Farrar, Straus and Giroux
Review Posted Online: Sept. 3, 2011
Kirkus Reviews Issue: Sept. 15, 2011
BOOK REVIEW
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