Highly recommended: an exceptionally well-organized, authoritative, and readable resource book.
A valuable resource for those wondering whether there is a chance that cancer runs in their family.
Ross (Director, Cancer Genetics Program/Univ. of Texas Southwestern Medical Center) has the ideal background: oncologist, cancer survivor who carries a cancer gene mutation, and cancer gene researcher with a mission to help people. She sends an upbeat message that learning about a cancer mutation in one’s family history is not about coping with bad news; it is about taking control and making choices. Although readers learn about the author’s decision-making process when she discovered the risks of her mutant gene, she does not claim that they were the best choices at the time nor does she prescribe what choices others should make. She organizes her information with great care and clarity, and thankfully, she lightens the reading with her personal story and those of the cancer patients she has known. Ross explains how cancer mutations are passed through families, how to recognize the signs of a cancer mutation, how to create a revealing family tree, how to get genetic counseling and genetic testing, and how to tell family members that they may be at risk, often information they may not want to hear. Furthermore, she describes how to manage one’s risk when experts give conflicting information or when information is limited. The chapter on targeted treatments, subtitled “Realities, Myths, Possibilities,” is sometimes a bit technical, but Ross calmly advises readers to evaluate current research on new treatments in the same way they researched their family history: with persistence, honesty, and toleration for the discomfort of not knowing. Appendices provide additional practical information on inherited cancer syndromes and their risk management, and a resource list contains the names and websites of helpful support organizations.
Highly recommended: an exceptionally well-organized, authoritative, and readable resource book.Pub Date: Feb. 2, 2016
ISBN: 978-1-101-98283-9
Page Count: 304
Publisher: Avery
Review Posted Online: Nov. 10, 2015
Kirkus Reviews Issue: Dec. 1, 2015
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...
A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.
Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.Pub Date: Jan. 19, 2016
ISBN: 978-0-8129-8840-6
Page Count: 248
Publisher: Random House
Review Posted Online: Sept. 29, 2015
Kirkus Reviews Issue: Oct. 15, 2015
If the authors are serious, this is a silly, distasteful book. If they are not, it’s a brilliant satire.
The authors have created a sort of anti-Book of Virtues in this encyclopedic compendium of the ways and means of power.
Everyone wants power and everyone is in a constant duplicitous game to gain more power at the expense of others, according to Greene, a screenwriter and former editor at Esquire (Elffers, a book packager, designed the volume, with its attractive marginalia). We live today as courtiers once did in royal courts: we must appear civil while attempting to crush all those around us. This power game can be played well or poorly, and in these 48 laws culled from the history and wisdom of the world’s greatest power players are the rules that must be followed to win. These laws boil down to being as ruthless, selfish, manipulative, and deceitful as possible. Each law, however, gets its own chapter: “Conceal Your Intentions,” “Always Say Less Than Necessary,” “Pose as a Friend, Work as a Spy,” and so on. Each chapter is conveniently broken down into sections on what happened to those who transgressed or observed the particular law, the key elements in this law, and ways to defensively reverse this law when it’s used against you. Quotations in the margins amplify the lesson being taught. While compelling in the way an auto accident might be, the book is simply nonsense. Rules often contradict each other. We are told, for instance, to “be conspicuous at all cost,” then told to “behave like others.” More seriously, Greene never really defines “power,” and he merely asserts, rather than offers evidence for, the Hobbesian world of all against all in which he insists we live. The world may be like this at times, but often it isn’t. To ask why this is so would be a far more useful project.
If the authors are serious, this is a silly, distasteful book. If they are not, it’s a brilliant satire.Pub Date: Sept. 1, 1998
ISBN: 0-670-88146-5
Page Count: 430
Publisher: Viking
Review Posted Online: May 19, 2010
Kirkus Reviews Issue: July 15, 1998
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