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CAN’T REMEMBER WHAT I FORGOT

THE GOOD NEWS FROM THE FRONT LINES OF MEMORY RESEARCH

High-quality science writing: an illuminating picture of investigators at work and a lucid explication of their findings.

Engrossing review of the latest advances in the science of memory and brain disease.

During the 1990s, Alzheimer’s replaced AIDS as an American mass phobia, writes veteran science journalist Halpern (The Book of Hard Things, 2003, etc.). Polls place Alzheimer’s second after cancer as the nation’s most feared disease, and it’s first among those older than 55. But, like thinning hair and wrinkles, memory problems occur during normal aging, she informs us. This is cold comfort to anyone who loses her keys or forgets to pay the phone bill, lapses that stimulated the middle-aged author to “get her head examined” and quiz the scientists doing the examining. Halpern intermixes her own experiences with interviews. Her subjects, most of them university faculty, do a good job explaining how we remember, what can go wrong and what they are doing about it. Heredity plays a role, but despite headlines regularly announcing the discovery of the Alzheimer’s gene, it’s unlikely that a single genetic trigger exists; instead, scientists have found plenty of genes that increase the risk. Detecting early memory loss has become a minor industry that often involves high-tech scans and MRIs, even though paper-and-pen tests work as well. (Halpern did both.) The author investigates research to boost memory and turns up one method that works: regular physical exercise. Folk wisdom to the contrary, doing crossword puzzles or math problems doesn’t help. Many drugs increase memory in animals; given to humans, their success rate remains steady at zero. There is as yet no “cure,” but Halpern stresses that breakthroughs occur much faster after scientists understand a disease, and Alzheimer’s is no longer the baffling puzzle it once was. Researchers with new ideas and high-tech equipment are turning up specific anatomical, molecular and genetic abnormalities that govern memory and its loss.

High-quality science writing: an illuminating picture of investigators at work and a lucid explication of their findings.

Pub Date: May 6, 2008

ISBN: 978-0-307-40674-3

Page Count: 272

Publisher: Harmony

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: April 1, 2008

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WHY WE SWIM

An absorbing, wide-ranging story of humans’ relationship with the water.

A study of swimming as sport, survival method, basis for community, and route to physical and mental well-being.

For Bay Area writer Tsui (American Chinatown: A People's History of Five Neighborhoods, 2009), swimming is in her blood. As she recounts, her parents met in a Hong Kong swimming pool, and she often visited the beach as a child and competed on a swim team in high school. Midway through the engaging narrative, the author explains how she rejoined the team at age 40, just as her 6-year-old was signing up for the first time. Chronicling her interviews with scientists and swimmers alike, Tsui notes the many health benefits of swimming, some of which are mental. Swimmers often achieve the “flow” state and get their best ideas while in the water. Her travels took her from the California coast, where she dove for abalone and swam from Alcatraz back to San Francisco, to Tokyo, where she heard about the “samurai swimming” martial arts tradition. In Iceland, she met Guðlaugur Friðþórsson, a local celebrity who, in 1984, survived six hours in a winter sea after his fishing vessel capsized, earning him the nickname “the human seal.” Although humans are generally adapted to life on land, the author discovered that some have extra advantages in the water. The Bajau people of Indonesia, for instance, can do 10-minute free dives while hunting because their spleens are 50% larger than average. For most, though, it’s simply a matter of practice. Tsui discussed swimming with Dara Torres, who became the oldest Olympic swimmer at age 41, and swam with Kim Chambers, one of the few people to complete the daunting Oceans Seven marathon swim challenge. Drawing on personal experience, history, biology, and social science, the author conveys the appeal of “an unflinching giving-over to an element” and makes a convincing case for broader access to swimming education (372,000 people still drown annually).

An absorbing, wide-ranging story of humans’ relationship with the water.

Pub Date: April 14, 2020

ISBN: 978-1-61620-786-1

Page Count: 288

Publisher: Algonquin

Review Posted Online: Jan. 4, 2020

Kirkus Reviews Issue: Feb. 1, 2020

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THE IMMORTAL LIFE OF HENRIETTA LACKS

Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and...

A dense, absorbing investigation into the medical community's exploitation of a dying woman and her family's struggle to salvage truth and dignity decades later.

In a well-paced, vibrant narrative, Popular Science contributor and Culture Dish blogger Skloot (Creative Writing/Univ. of Memphis) demonstrates that for every human cell put under a microscope, a complex life story is inexorably attached, to which doctors, researchers and laboratories have often been woefully insensitive and unaccountable. In 1951, Henrietta Lacks, an African-American mother of five, was diagnosed with what proved to be a fatal form of cervical cancer. At Johns Hopkins, the doctors harvested cells from her cervix without her permission and distributed them to labs around the globe, where they were multiplied and used for a diverse array of treatments. Known as HeLa cells, they became one of the world's most ubiquitous sources for medical research of everything from hormones, steroids and vitamins to gene mapping, in vitro fertilization, even the polio vaccine—all without the knowledge, must less consent, of the Lacks family. Skloot spent a decade interviewing every relative of Lacks she could find, excavating difficult memories and long-simmering outrage that had lay dormant since their loved one's sorrowful demise. Equal parts intimate biography and brutal clinical reportage, Skloot's graceful narrative adeptly navigates the wrenching Lack family recollections and the sobering, overarching realities of poverty and pre–civil-rights racism. The author's style is matched by a methodical scientific rigor and manifest expertise in the field.

Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and Petri dish politics.

Pub Date: Feb. 9, 2010

ISBN: 978-1-4000-5217-2

Page Count: 320

Publisher: Crown

Review Posted Online: Dec. 22, 2010

Kirkus Reviews Issue: Jan. 1, 2010

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