A hard-hitting and timely report on a pervasive threat.
Deadly germs escape from advanced laboratories with alarming and perhaps catastrophic consequences, according to this sobering nonfiction book.
Investigative journalist Young, who’s worked as a reporter and editor for such outlets as USA Today, the Detroit Free Press, and the Atlanta Journal-Constitution, explores lapses, accidents, and disasters at high-containment Biosafety Level 2, 3, and 4 laboratories around the world. They include a 1978 smallpox outbreak at a lab at Britain’s Birmingham University that resulted in the world’s last smallpox death (in which the remorseful lab director committed suicide); a 1979 anthrax release from a Soviet bioweapons lab in Sverdlovsk, which killed dozens of people; several leaks of contaminated wastewater at the U.S. Army’s Fort Detrick biological research institute in 2018, which may have traveled to the nearby town of Frederick, Maryland; a lab tech’s death from a bacterial infection in a San Francisco Veterans Administration medical center; several leaks of a SARS-associate coronavirus from Asian labs in 2003 and 2004, resulting in one death; and the exposure of lab workers to engineered microbes during “gain of function” research that seeks to make pathogens more infectious. A lengthy chapter explores the possibility that the Covid-19 pandemic was caused by a virus that escaped from the Wuhan Institute of Virology. Young dives deeply into how lab safeguards can fail because of equipment breakdowns, leaky pipes, holes in biohazard suits, mislabeled vials, accidental needle sticks, and other circumstances. The book also offers an absorbing account of Young’s own dogged reporting as she visits labs (she once found a high-tech containment-lab door sealed shut with duct tape), pries information out of reluctant officials, and receives tips from anonymous sources. She renders scientific issues in lucid, accessible prose that vividly conveys the insidious nature of potentially lethal microbes: “Other liquid or solid particles were so small they became airborne, spreading on invisible air currents, pushed along by heating and cooling systems, the opening and closing of doors, and the movement of people between rooms and down hallways.” Throughout, Young shows just how perilous infectious-disease research can be.
A hard-hitting and timely report on a pervasive threat.Pub Date: April 25, 2023
ISBN: 9781546002932
Page Count: 352
Publisher: Center Street/Hachette
Review Posted Online: Sept. 22, 2023
Kirkus Reviews Issue: Nov. 1, 2023
Review Program: Kirkus Indie
BOOK REVIEW
PERSPECTIVES
A short, smart analysis of perhaps the most famous passage in American history reveals its potency and unfulfilled promise.
Words that made a nation.
Isaacson is known for expansive biographies of great thinkers (and Elon Musk), but here he pens a succinct, stimulating commentary on the Founding Fathers’ ode to “life, liberty, and the pursuit of happiness.” His close reading of the Declaration of Independence’s second sentence, published to mark the 250th anniversary of the document’s adoption, doesn’t downplay its “moral contradiction.” Thomas Jefferson enslaved hundreds of people yet called slavery “a cruel war against human nature” in his first draft of the Declaration. All but 15 of the document’s 56 signers owned enslaved people. While the sentence in question asserted “all men are created equal” and possess “unalienable rights,” the Founders “consciously and intentionally” excluded women, Native Americans, and enslaved people. And yet the sentence is powerful, Isaacson writes, because it names a young nation’s “aspirations.” He mounts a solid defense of what ought to be shared goals, among them economic fairness, “moral compassion,” and a willingness to compromise. “Democracy depends on this,” he writes. Isaacson is excellent when explaining how Enlightenment intellectuals abroad influenced the founders. Benjamin Franklin, one of the Declaration’s “five-person drafting committee,” stayed in David Hume’s home for a month in the early 1770s, “discussing ideas of natural rights” with the Scottish philosopher. Also strong is Isaacson’s discussion of the “edits and tweaks” made to Jefferson’s draft. As recommended by Franklin and others, the changes were substantial, leaving Jefferson “distraught.” Franklin, who emerges as the book’s hero, helped establish municipal services, founded a library, and encouraged religious diversity—the kind of civic-mindedness that we could use more of today, Isaacson reminds us.
A short, smart analysis of perhaps the most famous passage in American history reveals its potency and unfulfilled promise.Pub Date: Nov. 18, 2025
ISBN: 9781982181314
Page Count: 80
Publisher: Simon & Schuster
Review Posted Online: Aug. 29, 2025
Kirkus Reviews Issue: Oct. 1, 2025
BOOK REVIEW
BOOK REVIEW
BOOK REVIEW
SEEN & HEARD
Cogent, well-timed ideas for meeting today’s biggest challenges.
Helping liberals get out of their own way.
Klein, a New York Times columnist, and Thompson, an Atlantic staffer, lean to the left, but they aren’t interrogating the usual suspects. Aware that many conservatives have no interest in their opinions, the authors target their own side’s “pathologies.” Why do red states greenlight the kind of renewable energy projects that often languish in blue states? Why does liberal California have the nation’s most severe homelessness and housing affordability crises? One big reason: Liberal leadership has ensnared itself in a web of well-intentioned yet often onerous “goals, standards, and rules.” This “procedural kludge,” partially shaped by lawyers who pioneered a “democracy by lawsuit” strategy in the 1960s, threatens to stymie key breakthroughs. Consider the anti-pollution laws passed after World War II. In the decades since, homeowners’ groups in liberal locales have cited such statutes in lawsuits meant to stop new affordable housing. Today, these laws “block the clean energy projects” required to tackle climate change. Nuclear energy is “inarguably safer” than the fossil fuel variety, but because Washington doesn’t always “properly weigh risk,” it almost never builds new reactors. Meanwhile, technologies that may cure disease or slash the carbon footprint of cement production benefit from government support, but too often the grant process “rewards caution and punishes outsider thinking.” The authors call this style of governing “everything-bagel liberalism,” so named because of its many government mandates. Instead, they envision “a politics of abundance” that would remake travel, work, and health. This won’t happen without “changing the processes that make building and inventing so hard.” It’s time, then, to scrutinize everything from municipal zoning regulations to the paperwork requirements for scientists getting federal funding. The authors’ debut as a duo is very smart and eminently useful.
Cogent, well-timed ideas for meeting today’s biggest challenges.Pub Date: March 18, 2025
ISBN: 9781668023488
Page Count: 288
Publisher: Avid Reader Press
Review Posted Online: Jan. 16, 2025
Kirkus Reviews Issue: Feb. 15, 2025
BOOK REVIEW
PERSPECTIVES
SEEN & HEARD
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