A good education on addiction, fascinating case histories, and a sensible formula for treatment.
An addiction specialist discusses her patients’ problems and how she deals with them, and it’s an unsettling picture.
Lembke, medical director of the Stanford Addiction Medicine clinic, begins with a lesson in neuroscience. Nerves along brain pathways that process rewards (i.e., pleasure) use dopamine as a “neurotransmitter”—to deliver signals. The more dopamine an experience releases, the more we enjoy it. However, dopamine processes pain as well as pleasure, and a healthy brain maintains a balance. Most of us stop eating when we feel full. Coffee often provides all the stimulation we need. Gambling, drinking, shopping, or watching pornography are intermittent activities. Addiction, the mark of an unhealthy brain, is a compulsive behavior that continues despite the harm it causes, and it’s a worldwide epidemic. The biggest risk factor is easy access. History books proclaim Prohibition a failure, but it produced a big drop in alcoholism, public drunkenness, and alcohol-caused liver disease, which rose again after repeal. Today, it seems, all indulgences are accessible. Since around 2000, the rampant overprescription of narcotics has produced skyrocketing addiction and death. The internet allows us to engage in social as well as unseemly activities in private. Popular medical books rely on vivid case histories, and Lembke offers plenty. Her first is a lifelong masturbation addict who was ultimately able to achieve control. There follow accounts of other types of addicts, and she describes her treatment strategy based on the acronym DOPAMINE: data, objectives, problems, abstinence, mindfulness, insight, next steps, and experiment. Most readers will find it reasonable, and the author does not trumpet its success rate. Some of the most insightful passages involve lying, a malignant process in a cooperative society but essential to maintaining addictive behavior. Many people believe that honesty—unmasking our flaws—will drive people away, but it does the opposite.
A good education on addiction, fascinating case histories, and a sensible formula for treatment.Pub Date: Aug. 24, 2021
ISBN: 978-1-5247-4672-8
Page Count: 304
Publisher: Dutton
Review Posted Online: June 15, 2021
Kirkus Reviews Issue: July 1, 2021
A powerful reiteration of principles—and some fresh ideas—from the longest-serving independent in congressional history.
Another chapter in a long fight against inequality.
Building on his Fighting Oligarchy tour, which this year drew 280,000 people to rallies in red and blue states, Sanders amplifies his enduring campaign for economic fairness. The Vermont senator offers well-timed advice for combating corruption and issues a robust plea for national soul-searching. His argument rests on alarming data on the widening wealth gap’s impact on democracy. Bolstered by a 2010 Supreme Court decision that removed campaign finance limits, “100 billionaire families spent $2.6 billion” on 2024 elections. Sanders focuses on the Trump administration and congressional Republicans, describing their enactment of the “Big Beautiful Bill,” with its $1 trillion in tax breaks for the richest Americans and big social safety net cuts, as the “largest transfer of wealth” in living memory. But as is his custom, he spreads the blame, dinging Democrats for courting wealthy donors while ignoring the “needs and suffering” of the working class. “Trump filled the political vacuum that the Democrats created,” he writes, a resonant diagnosis. Urging readers not to surrender to despair, Sanders offers numerous legislative proposals. These would empower labor unions, cut the workweek to 32 hours, regulate campaign spending, reduce gerrymandering, and automatically register 18-year-olds to vote. Grassroots supporters can help by running for local office, volunteering with a campaign, and asking educators how to help support public schools. Meanwhile, Sanders asks us “to question the fundamental moral values that underlie” a system that enables “the top 1 percent” to “own more wealth than the bottom 93 percent.” Though his prose sometimes reads like a transcribed speech with built-in applause lines, Sanders’ ideas are specific, clear, and commonsensical. And because it echoes previous statements, his call for collective introspection lands as genuine.
A powerful reiteration of principles—and some fresh ideas—from the longest-serving independent in congressional history.Pub Date: Oct. 21, 2025
ISBN: 9798217089161
Page Count: 160
Publisher: Crown
Review Posted Online: Oct. 21, 2025
Kirkus Reviews Issue: Dec. 15, 2025
BOOK REVIEW
BOOK REVIEW
BOOK REVIEW
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...
A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.
Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.Pub Date: Jan. 19, 2016
ISBN: 978-0-8129-8840-6
Page Count: 248
Publisher: Random House
Review Posted Online: Sept. 29, 2015
Kirkus Reviews Issue: Oct. 15, 2015
PERSPECTIVES
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