Next book

HOW MEDICINE WORKS AND WHEN IT DOESN'T

LEARNING WHO TO TRUST TO GET AND STAY HEALTHY

In an unstinting appraisal of the profession, Wilson effectively diagnoses the issues and looks for new paths forward.

There is a crisis of trust permeating the medical profession, according to this insightful book by a leading researcher.

The practice of medicine is “a science of percentages, a science of intelligent guesses, a science of hedging bets,” writes Wilson, director of Yale’s Clinical and Translational Research Accelerator. “Medicine continues to evolve, with new discoveries overturning old beliefs, inching us closer to real truth.” The problem is that many patients do not want reasonable guesses but immediate, sure-fire answers. The gap has been filled by alternative healers, naturopaths, and internet marketers who provide diagnoses and cures that range from the esoteric to the foolish. What they are really selling, Wilson suggests, is certainty, a desirable commodity in a chaotic world. Most of the “cures” are harmless, some help patients via the placebo effect, and a few are actually dangerous. Yet the public perception of practitioners of alternative medicine is above that of the pharmaceutical industry. “The marketing of foxglove extract, reiki and qigong is peaceful and patient-centric,” writes the author. “And, of course, no one is paying $80,000 a year for Saint-John’s-wort.” Given these circumstances, Wilson argues persuasively that doctors should spend more time with patients instead of rushing them through as if on a conveyor belt. This would also give them the opportunity to explain the limitations of a proposed treatment. Equally, doctors should be ready to move away from drug-based solutions. Wilson sees an epidemic of “deaths of despair”: drugs, alcoholism, and suicide, driven by isolation and loneliness. These cannot be addressed with pills; lifestyle changes are needed, which means building a trust relationship. Mixing hard data with personal anecdotes, Wilson sets out a convincing case, and he does not ignore the difficulties of making these changes. If nothing is done, the prognosis for the practice of medicine is grim.

In an unstinting appraisal of the profession, Wilson effectively diagnoses the issues and looks for new paths forward.

Pub Date: Jan. 24, 2023

ISBN: 978-1-5387-2360-9

Page Count: 304

Publisher: Grand Central Publishing

Review Posted Online: Sept. 26, 2022

Kirkus Reviews Issue: Oct. 15, 2022

Awards & Accolades

Likes

  • Readers Vote
  • 107


Our Verdict

  • Our Verdict
  • GET IT


Google Rating

  • google rating
  • google rating
  • google rating
  • google rating
  • google rating

  • Kirkus Reviews'
    Best Books Of 2016


  • New York Times Bestseller


  • Pulitzer Prize Finalist

Next book

WHEN BREATH BECOMES AIR

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...

Awards & Accolades

Likes

  • Readers Vote
  • 107


Our Verdict

  • Our Verdict
  • GET IT


Google Rating

  • google rating
  • google rating
  • google rating
  • google rating
  • google rating

  • Kirkus Reviews'
    Best Books Of 2016


  • New York Times Bestseller


  • Pulitzer Prize Finalist

A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.

Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.

Pub Date: Jan. 19, 2016

ISBN: 978-0-8129-8840-6

Page Count: 248

Publisher: Random House

Review Posted Online: Sept. 29, 2015

Kirkus Reviews Issue: Oct. 15, 2015

Awards & Accolades

Likes

  • Readers Vote
  • 73


Our Verdict

  • Our Verdict
  • GET IT


  • New York Times Bestseller

Next book

THE GREATEST SENTENCE EVER WRITTEN

A short, smart analysis of perhaps the most famous passage in American history reveals its potency and unfulfilled promise.

Awards & Accolades

Likes

  • Readers Vote
  • 73


Our Verdict

  • Our Verdict
  • GET IT


  • New York Times Bestseller

Words that made a nation.

Isaacson is known for expansive biographies of great thinkers (and Elon Musk), but here he pens a succinct, stimulating commentary on the Founding Fathers’ ode to “life, liberty, and the pursuit of happiness.” His close reading of the Declaration of Independence’s second sentence, published to mark the 250th anniversary of the document’s adoption, doesn’t downplay its “moral contradiction.” Thomas Jefferson enslaved hundreds of people yet called slavery “a cruel war against human nature” in his first draft of the Declaration. All but 15 of the document’s 56 signers owned enslaved people. While the sentence in question asserted “all men are created equal” and possess “unalienable rights,” the Founders “consciously and intentionally” excluded women, Native Americans, and enslaved people. And yet the sentence is powerful, Isaacson writes, because it names a young nation’s “aspirations.” He mounts a solid defense of what ought to be shared goals, among them economic fairness, “moral compassion,” and a willingness to compromise. “Democracy depends on this,” he writes. Isaacson is excellent when explaining how Enlightenment intellectuals abroad influenced the founders. Benjamin Franklin, one of the Declaration’s “five-person drafting committee,” stayed in David Hume’s home for a month in the early 1770s, “discussing ideas of natural rights” with the Scottish philosopher. Also strong is Isaacson’s discussion of the “edits and tweaks” made to Jefferson’s draft. As recommended by Franklin and others, the changes were substantial, leaving Jefferson “distraught.” Franklin, who emerges as the book’s hero, helped establish municipal services, founded a library, and encouraged religious diversity—the kind of civic-mindedness that we could use more of today, Isaacson reminds us.

A short, smart analysis of perhaps the most famous passage in American history reveals its potency and unfulfilled promise.

Pub Date: Nov. 18, 2025

ISBN: 9781982181314

Page Count: 80

Publisher: Simon & Schuster

Review Posted Online: Aug. 29, 2025

Kirkus Reviews Issue: Oct. 1, 2025

Close Quickview