Sound research and expert experience create an illuminating work on the potential benefits of interferon.
A scientist advocates the revival of an antiviral cancer treatment popular in the 1980s.
Cummins, a microbiologist and veterinarian, has produced an astute, thought-provoking, and convincing testament to the revitalization of low-dose interferon administration. The goal of his book—written with former attorney Heckenlively—is to renew clinical and public interest in the drug, which came into prominence in the early ’80s. Despite proven antiviral and anti-cancer properties in animals, the treatment failed to surpass the scientific community’s lofty expectations for it in human trials. Cummins, whose narrative perspective predominantly anchors the work, first charts his own interest and history in veterinary medicine and how his distinguished career in immunological research science prepared him to become a leading voice in interferon application advocacy for animals as well as humans. The volume describes interferon as a naturally occurring protein found in the human body during a viral infection that has been resoundingly beneficial for animals in veterinary arenas as well as helpful in providing broad protection to humans by shortening the duration of viral shedding. Although early Japanese and Russian studies bolstered low-dose interferon as an influenza prophylaxis, its widespread usage never materialized. Cummins embarked on a career researching oral human interferon and authoring many articles on its efficacy in trials. This study-heavy work shares the wealth of more than five decades of research backing interferon’s use, including controversial success stories, like a veterinarian who treated himself with the drug after contracting HIV; case studies with compromised patients; and media coverage. Parts of the narrative utilize scientific jargon that may confuse some lay readers, though others will find themselves persuaded by the sensible and science-supported arguments. Concluding chapters offer an update on the current state of more recent clinical trials and an enlightening lesson on viral behavior and how the immune system’s reaction to classic coronaviruses could prepare the human body’s defense mechanisms against SARS-CoV-2. Cummins gets personal in the closing pages, admitting to suffering from Parkinson’s disease and planning to relinquish his participation in the effort to reawaken interest in interferon usage. He asserts that interferon has its share of detractors who believe the drug “threatens to upend the pharmaceutical bottom line.”
Sound research and expert experience create an illuminating work on the potential benefits of interferon.Pub Date: Dec. 8, 2020
ISBN: 978-1-5107-6550-4
Page Count: 200
Publisher: Skyhorse Publishing
Review Posted Online: Dec. 1, 2020
Kirkus Reviews Issue: Jan. 15, 2021
Review Program: Kirkus Indie
BOOK REVIEW
The lessons to draw are obvious: Smoke more dope, eat less meat. Like-minded readers will dig it.
The chef, rapper, and TV host serves up a blustery memoir with lashings of self-help.
“I’ve always had a sick confidence,” writes Bronson, ne Ariyan Arslani. The confidence, he adds, comes from numerous sources: being a New Yorker, and more specifically a New Yorker from Queens; being “short and fucking husky” and still game for a standoff on the basketball court; having strength, stamina, and seemingly no fear. All these things serve him well in the rough-and-tumble youth he describes, all stickball and steroids. Yet another confidence-builder: In the big city, you’ve got to sink or swim. “No one is just accepted—you have to fucking show that you’re able to roll,” he writes. In a narrative steeped in language that would make Lenny Bruce blush, Bronson recounts his sentimental education, schooled by immigrant Italian and Albanian family members and the mean streets, building habits good and bad. The virtue of those habits will depend on your take on modern mores. Bronson writes, for example, of “getting my dick pierced” down in the West Village, then grabbing a pizza and smoking weed. “I always smoke weed freely, always have and always will,” he writes. “I’ll just light a blunt anywhere.” Though he’s gone through the classic experiences of the latter-day stoner, flunking out and getting arrested numerous times, Bronson is a hard charger who’s not afraid to face nearly any challenge—especially, given his physique and genes, the necessity of losing weight: “If you’re husky, you’re always dieting in your mind,” he writes. Though vulgar and boastful, Bronson serves up a model that has plenty of good points, including his growing interest in nature, creativity, and the desire to “leave a legacy for everybody.”
The lessons to draw are obvious: Smoke more dope, eat less meat. Like-minded readers will dig it.Pub Date: April 20, 2021
ISBN: 978-1-4197-4478-5
Page Count: 184
Publisher: Abrams
Review Posted Online: May 5, 2021
Kirkus Reviews Issue: June 1, 2021
An absorbing, wide-ranging story of humans’ relationship with the water.
A study of swimming as sport, survival method, basis for community, and route to physical and mental well-being.
For Bay Area writer Tsui (American Chinatown: A People's History of Five Neighborhoods, 2009), swimming is in her blood. As she recounts, her parents met in a Hong Kong swimming pool, and she often visited the beach as a child and competed on a swim team in high school. Midway through the engaging narrative, the author explains how she rejoined the team at age 40, just as her 6-year-old was signing up for the first time. Chronicling her interviews with scientists and swimmers alike, Tsui notes the many health benefits of swimming, some of which are mental. Swimmers often achieve the “flow” state and get their best ideas while in the water. Her travels took her from the California coast, where she dove for abalone and swam from Alcatraz back to San Francisco, to Tokyo, where she heard about the “samurai swimming” martial arts tradition. In Iceland, she met Guðlaugur Friðþórsson, a local celebrity who, in 1984, survived six hours in a winter sea after his fishing vessel capsized, earning him the nickname “the human seal.” Although humans are generally adapted to life on land, the author discovered that some have extra advantages in the water. The Bajau people of Indonesia, for instance, can do 10-minute free dives while hunting because their spleens are 50% larger than average. For most, though, it’s simply a matter of practice. Tsui discussed swimming with Dara Torres, who became the oldest Olympic swimmer at age 41, and swam with Kim Chambers, one of the few people to complete the daunting Oceans Seven marathon swim challenge. Drawing on personal experience, history, biology, and social science, the author conveys the appeal of “an unflinching giving-over to an element” and makes a convincing case for broader access to swimming education (372,000 people still drown annually).
An absorbing, wide-ranging story of humans’ relationship with the water.Pub Date: April 14, 2020
ISBN: 978-1-61620-786-1
Page Count: 288
Publisher: Algonquin
Review Posted Online: Jan. 4, 2020
Kirkus Reviews Issue: Feb. 1, 2020
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