Medical memoirs have become a significant genre over the past two decades, and this one ranks near the top, in a class that...
An outstanding memoir by a transplant surgeon who combines an autobiography and operating room dramatics with an equally engrossing history of his profession.
In his first book, Mezrich (Surgery/Univ. of Wisconsin School of Medicine and Public Health) avoids standard-issue jokes about motorcyclists who don’t wear helmets but reminds readers that, except for the occasional live donor, a tragedy usually precedes every transplant. “Someone who had just died had saved the life of someone he had never met,” he writes, “and we were the ones that made it happen.” The author touches all bases with a masterly hand. He trained as a surgery resident, undergoing the usual mixture of servitude and inspiration. He graduated to a fellowship, during which skill and satisfaction increased with no decrease in the workload. Readers will share the author’s exhilaration at the end of a procedure when, for example, the clamps are released, blood flow turns a new kidney pink, and urine flows out before his eyes. At intervals, the author digresses, offering a cogent history of transplants. These sections will enthrall most readers save animal rights proponents, who will recoil at the myriad of animals sacrificed along the way. However, plenty of human recipients also died miserably, except for the rare identical twin, in the decades before doctors realized that they required immunosuppression. About half died during the 1960s and ’70s, when surgeons used early versions of anti-rejection drugs. After the first effective immunosuppressant, cyclosporine, was approved by the Food and Drug Administration in 1983, success rates exceeded 90 percent. As a result, transplanting many organs has become routine. Still, recent doctor-authors give equal time to failures, so Mezrich recounts plenty of painful experiences.
Medical memoirs have become a significant genre over the past two decades, and this one ranks near the top, in a class that includes arguably the best, Henry Marsh’s Do No Harm (2015).Pub Date: Jan. 15, 2019
ISBN: 978-0-06-265620-9
Page Count: 368
Publisher: Harper/HarperCollins
Review Posted Online: Oct. 1, 2018
Kirkus Reviews Issue: Oct. 15, 2018
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...
A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.
Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.Pub Date: Jan. 19, 2016
ISBN: 978-0-8129-8840-6
Page Count: 248
Publisher: Random House
Review Posted Online: Sept. 29, 2015
Kirkus Reviews Issue: Oct. 15, 2015
PERSPECTIVES
This autobiography might almost be said to supply the roots to Wright's famous novel, Native Son.
It is a grim record, disturbing, the story of how — in one boy's life — the seeds of hate and distrust and race riots were planted. Wright was born to poverty and hardship in the deep south; his father deserted his mother, and circumstances and illness drove the little family from place to place, from degradation to degradation. And always, there was the thread of fear and hate and suspicion and discrimination — of white set against black — of black set against Jew — of intolerance. Driven to deceit, to dishonesty, ambition thwarted, motives impugned, Wright struggled against the tide, put by a tiny sum to move on, finally got to Chicago, and there — still against odds — pulled himself up, acquired some education through reading, allied himself with the Communists — only to be thrust out for non-conformity — and wrote continually. The whole tragedy of a race seems dramatized in this record; it is virtually unrelieved by any vestige of human tenderness, or humor; there are no bright spots. And yet it rings true. It is an unfinished story of a problem that has still to be met.
Perhaps this will force home unpalatable facts of a submerged minority, a problem far from being faced.
Pub Date: Feb. 28, 1945
ISBN: 0061130249
Page Count: 450
Publisher: N/A
Review Posted Online: Oct. 7, 2011
Kirkus Reviews Issue: Feb. 1, 1945
BOOK REVIEW
BOOK REVIEW
BOOK REVIEW
© Copyright 2025 Kirkus Media LLC. All Rights Reserved.
Follow
Popular in this Genre
We can’t wait for you to join Kirkus!
It’s free and takes less than 10 seconds!
Already have an account? Log in.
OR
Sign in with GoogleTrouble signing in? Retrieve credentials.
Welcome Back!
OR
Sign in with GoogleTrouble signing in? Retrieve credentials.
