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GOOD CHEMISTRY

THE SCIENCE OF CONNECTION, FROM SOUL TO PSYCHEDELICS

An intriguing invitation to tune into the therapeutic experience of psychedelic connectivity.

It’s hard to argue the fact that we are losing our human-to-human connection. One way back, suggests Holland, a psychiatrist who specializes in psychopharmacology, is via psychedelic medicines.

To reproduce, nurture, and survive, humans are hard-wired for connection, but our current state is one of disconnection and isolation. However, as the author writes in this enthusiastic foray into the possibilities of igniting the “pharmacological fireworks in our brains,” we have the potential “to bring us back into alignment with our true purpose, which is connection.” Social isolation “has a lethality on par with being obese, or with smoking about fifteen cigarettes a day.” One expression of it is our obsession with screens; another is the opioid epidemic. Via her personal experience, interviews with experts, and a sturdy grasp of the medical literature, Holland explains the monitored use of MDMA, LSD, THC, and psilocybin mushrooms to “light a path out of chronic loneliness and toward connectedness.” The author, who edited The Pot Book: A Complete Guide to Cannabis (2010) and Ecstasy: The Complete Guide (2001), ranges among connections with the self, a partner, family, community, Earth, and the cosmos. One of Holland’s most important aims—and one that will ring true for many readers—is to tap into the parasympathetic nervous system, the flip side of the fight-or-flight state, the mode when we feel relaxed, safe, loving, and loved. There are many states of chronic stress, loneliness, addiction, and alienation that can be addressed by using the best drugs available for orchestrating the process of attachment, and they are already in your brain—e.g., oxytocin, vasopressin, serotonin, endorphins, endocannabinoids, and dopamine. Holland explores a number of avenues to access this feel-good chemistry—conscious breathing, sex, meditation, group activities—and she conveys great excitement and marvelous anecdotes about the prospects of the psychedelic pharmacopeia.

An intriguing invitation to tune into the therapeutic experience of psychedelic connectivity.

Pub Date: June 16, 2020

ISBN: 978-0-06-286288-4

Page Count: 320

Publisher: Harper Wave

Review Posted Online: April 4, 2020

Kirkus Reviews Issue: May 1, 2020

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POEMS & PRAYERS

It’s not Shakespeare, not by a long shot. But at least it’s not James Franco.

A noted actor turns to verse: “Poems are a Saturday in the middle of the week.”

McConaughey, author of the gracefully written memoir Greenlights, has been writing poems since his teens, closing with one “written in an Australian bathtub” that reads just as a poem by an 18-year-old (Rimbaud excepted) should read: “Ignorant minds of the fortunate man / Blind of the fate shaping every land.” McConaughey is fearless in his commitment to the rhyme, no matter how slight the result (“Oops, took a quick peek at the sky before I got my glasses, / now I can’t see shit, sure hope this passes”). And, sad to say, the slight is what is most on display throughout, punctuated by some odd koanlike aperçus: “Eating all we can / at the all-we-can-eat buffet, / gives us a 3.8 education / and a 4.2 GPA.” “Never give up your right to do the next right thing. This is how we find our way home.” “Memory never forgets. Even though we do.” The prayer portion of the program is deeply felt, but it’s just as sentimental; only when he writes of life-changing events—a court appearance to file a restraining order against a stalker, his decision to quit smoking weed—do we catch a glimpse of the effortlessly fluent, effortlessly charming McConaughey as exemplified by the David Wooderson (“alright, alright, alright”) of Dazed and Confused. The rest is mostly a soufflé in verse. McConaughey’s heart is very clearly in the right place, but on the whole the book suggests an old saw: Don’t give up your day job.

It’s not Shakespeare, not by a long shot. But at least it’s not James Franco.

Pub Date: Sept. 16, 2025

ISBN: 9781984862105

Page Count: 208

Publisher: Crown

Review Posted Online: Aug. 15, 2025

Kirkus Reviews Issue: Sept. 15, 2025

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CALL ME ANNE

A sweet final word from an actor who leaves a legacy of compassion and kindness.

The late actor offers a gentle guide for living with more purpose, love, and joy.

Mixing poetry, prescriptive challenges, and elements of memoir, Heche (1969-2022) delivers a narrative that is more encouraging workbook than life story. The author wants to share what she has discovered over the course of a life filled with abuse, advocacy, and uncanny turning points. Her greatest discovery? Love. “Open yourself up to love and transform kindness from a feeling you extend to those around you to actions that you perform for them,” she writes. “Only by caring can we open ourselves up to the universe, and only by opening up to the universe can we fully experience all the wonders that it holds, the greatest of which is love.” Throughout the occasionally overwrought text, Heche is heavy on the concept of care. She wants us to experience joy as she does, and she provides a road map for how to get there. Instead of slinking away from Hollywood and the ridicule that she endured there, Heche found the good and hung on, with Alec Baldwin and Harrison Ford starring as particularly shining knights in her story. Some readers may dismiss this material as vapid Hollywood stuff, but Heche’s perspective is an empathetic blend of Buddhism (minimize suffering), dialectical behavioral therapy (tolerating distress), Christianity (do unto others), and pre-Socratic philosophy (sufficient reason). “You’re not out to change the whole world, but to increase the levels of love and kindness in the world, drop by drop,” she writes. “Over time, these actions wear away the coldness, hate, and indifference around us as surely as water slowly wearing away stone.” Readers grieving her loss will take solace knowing that she lived her love-filled life on her own terms. Heche’s business and podcast partner, Heather Duffy, writes the epilogue, closing the book on a life well lived.

A sweet final word from an actor who leaves a legacy of compassion and kindness.

Pub Date: Jan. 24, 2023

ISBN: 9781627783316

Page Count: 176

Publisher: Viva Editions

Review Posted Online: Feb. 6, 2023

Kirkus Reviews Issue: March 1, 2023

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