A portrait that captures not only the man, but also the end-of-the-19th-century dynamism that fostered revolutions in art,...
A resurrection of the life of “one of the founding fathers of immunology,” Elie Metchnikoff (1845-1916).
Vikhanski (In Search of the Lost Cord: Solving the Mystery of Spinal Cord Regeneration, 2001, etc.), a Russian-born, Israel-based science journalist, was initially dismissive of the achievements of the Ukrainian-born scientist, depicted as a great Russian hero in her school texts, a depiction she thought was merely Soviet propaganda. What she discovered sheds light on a critical period in medical and cultural history. Germ theory advanced greatly under Louis Pasteur in France and Robert Koch in Germany, and vaccines and serum treatments were developed to prevent or cure disease. Yet next to nothing was known about the body’s natural defenses. Enter Metchnikoff, a zoologist and fervent Darwinian who believed the study of simple organisms could reveal protective mechanisms that would be preserved in higher forms of life. His great epiphany occurred when he used rose thorns to invade the body of a transparent marine organism and, under the microscope, saw the mobilization of cells that engulfed and chewed up the thorns. He called them phagocytes (cell-eaters) and declared them the body’s chief defenders. Meanwhile, scientists in Germany had discovered antibodies. The resulting “Immunity War” pitted French scientists at the Pasteur Institute (where Metchnikoff settled for the remainder of his career) against the Germans. Eventually, the war waned, and Metchnikoff and Paul Ehrlich were jointly awarded a Nobel Prize. Only much later did scientists realize that Metchnikoff’s phagocytes reflected “innate immunity,” an evolutionarily older defense system compared to the “adaptive immunity” represented by antibodies. Metchnikoff went on to develop theories of aging and ideas about gut microbes that spawned a global yogurt revolution. As Vikhanski richly illustrates, Metchnikoff did everything with passion, in both his professional and personal lives.
A portrait that captures not only the man, but also the end-of-the-19th-century dynamism that fostered revolutions in art, politics, and science.Pub Date: April 1, 2016
ISBN: 978-1-61373-110-9
Page Count: 336
Publisher: Chicago Review Press
Review Posted Online: Jan. 12, 2016
Kirkus Reviews Issue: Feb. 1, 2016
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...
A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.
Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.Pub Date: Jan. 19, 2016
ISBN: 978-0-8129-8840-6
Page Count: 248
Publisher: Random House
Review Posted Online: Sept. 29, 2015
Kirkus Reviews Issue: Oct. 15, 2015
PERSPECTIVES
Well-told and admonitory.
Young-rags-to-mature-riches memoir by broker and motivational speaker Gardner.
Born and raised in the Milwaukee ghetto, the author pulled himself up from considerable disadvantage. He was fatherless, and his adored mother wasn’t always around; once, as a child, he spied her at a family funeral accompanied by a prison guard. When beautiful, evanescent Moms was there, Chris also had to deal with Freddie “I ain’t your goddamn daddy!” Triplett, one of the meanest stepfathers in recent literature. Chris did “the dozens” with the homies, boosted a bit and in the course of youthful adventure was raped. His heroes were Miles Davis, James Brown and Muhammad Ali. Meanwhile, at the behest of Moms, he developed a fondness for reading. He joined the Navy and became a medic (preparing badass Marines for proctology), and a proficient lab technician. Moving up in San Francisco, married and then divorced, he sold medical supplies. He was recruited as a trainee at Dean Witter just around the time he became a homeless single father. All his belongings in a shopping cart, Gardner sometimes slept with his young son at the office (apparently undiscovered by the night cleaning crew). The two also frequently bedded down in a public restroom. After Gardner’s talents were finally appreciated by the firm of Bear Stearns, his American Dream became real. He got the cool duds, hot car and fine ladies so coveted from afar back in the day. He even had a meeting with Nelson Mandela. Through it all, he remained a prideful parent. His own no-daddy blues are gone now.
Well-told and admonitory.Pub Date: June 1, 2006
ISBN: 0-06-074486-3
Page Count: 320
Publisher: Amistad/HarperCollins
Review Posted Online: May 19, 2010
Kirkus Reviews Issue: March 15, 2006
© Copyright 2025 Kirkus Media LLC. All Rights Reserved.
Follow
Popular in this Genre
We can’t wait for you to join Kirkus!
It’s free and takes less than 10 seconds!
Already have an account? Log in.
OR
Sign in with GoogleTrouble signing in? Retrieve credentials.
Welcome Back!
OR
Sign in with GoogleTrouble signing in? Retrieve credentials.
