The autobiography of a virology pioneer, the natural history of HIV/AIDS, and the story of the effort to combat the disease, all intertwined in an entertaining and enlightening package. The eminent virologist Montagnier, of the equally eminent Pasteur Institute in Paris, explains how he haphazardly found his way into his specialty. A childhood in France marred by the Occupation was followed by increasingly specialized work in medicine and biology. He makes breathtakingly clear the importance of ongoing AIDS research: 34 million people are living with HIV/AIDS; in 1998, 5.8 million were newly infected with HIV; 6,000 children are infected each day; the epidemic is spreading especially quickly in South Africa, Zimbabwe, Zambia, India, Cambodia, and southern China. Montagnier first looks at “Discovery,” how research—and clinical medicine’sometimes proceeds systematically along and sometimes stumbles by chance onto new diseases and treatments. He then details his own work identifying the causes and mechanisms by which HIV effects its damage. Montagnier, ever the gentleman, recounts with a forgiving tone his much-publicized dust-up with Robert Gallo of the National Institutes of Health; the two made key discoveries about the nature and mechanism of HIV virtually simultaneously, leading to difficulties with patents and funding. As he has in the past, Montagnier emerges as the voice of perspective and reason: “I admit that I stand apart from Robert Gallo on many matters. Nevertheless, we shared one important thing . . . the desperate, despairing search for retroviruses linked to human cancers.” Montagnier goes on to discuss the natural history of the disease and of the epidemic. He then looks at treatment, covering not just the scientific aspect but, most notably and sympathetically, devoting a chapter specifically to addressing those with the virus. After diagnosis, he understands, “Everyday life must be conceived and organized in another fashion, work and relationships with others reconsidered.” Elucidating explanation from the forefront of HIV/AIDS research, always with a strong humanitarian underpinning.
Pub Date: Nov. 1, 1999
ISBN: 0-393-03923-4
Page Count: 256
Publisher: Norton
Review Posted Online: May 19, 2010
Kirkus Reviews Issue: Sept. 15, 1999
An intriguing meditation on the nature of the universe and our attempts to understand it that should appeal to both...
Italian theoretical physicist Rovelli (General Relativity: The Most Beautiful of Theories, 2015, etc.) shares his thoughts on the broader scientific and philosophical implications of the great revolution that has taken place over the past century.
These seven lessons, which first appeared as articles in the Sunday supplement of the Italian newspaper Sole 24 Ore, are addressed to readers with little knowledge of physics. In less than 100 pages, the author, who teaches physics in both France and the United States, cogently covers the great accomplishments of the past and the open questions still baffling physicists today. In the first lesson, he focuses on Einstein's theory of general relativity. He describes Einstein's recognition that gravity "is not diffused through space [but] is that space itself" as "a stroke of pure genius." In the second lesson, Rovelli deals with the puzzling features of quantum physics that challenge our picture of reality. In the remaining sections, the author introduces the constant fluctuations of atoms, the granular nature of space, and more. "It is hardly surprising that there are more things in heaven and earth, dear reader, than have been dreamed of in our philosophy—or in our physics,” he writes. Rovelli also discusses the issues raised in loop quantum gravity, a theory that he co-developed. These issues lead to his extraordinary claim that the passage of time is not fundamental but rather derived from the granular nature of space. The author suggests that there have been two separate pathways throughout human history: mythology and the accumulation of knowledge through observation. He believes that scientists today share the same curiosity about nature exhibited by early man.
An intriguing meditation on the nature of the universe and our attempts to understand it that should appeal to both scientists and general readers.Pub Date: March 1, 2016
ISBN: 978-0-399-18441-3
Page Count: 96
Publisher: Riverhead
Review Posted Online: Dec. 7, 2015
Kirkus Reviews Issue: Dec. 15, 2015
BOOK REVIEW
BOOK REVIEW
Loads of good explaining, with reminders, time and again, of how much remains unknown, neatly putting the death of science...
Bryson (I'm a Stranger Here Myself, 1999, etc.), a man who knows how to track down an explanation and make it confess, asks the hard questions of science—e.g., how did things get to be the way they are?—and, when possible, provides answers.
As he once went about making English intelligible, Bryson now attempts the same with the great moments of science, both the ideas themselves and their genesis, to resounding success. Piqued by his own ignorance on these matters, he’s egged on even more so by the people who’ve figured out—or think they’ve figured out—such things as what is in the center of the Earth. So he goes exploring, in the library and in company with scientists at work today, to get a grip on a range of topics from subatomic particles to cosmology. The aim is to deliver reports on these subjects in terms anyone can understand, and for the most part, it works. The most difficult is the nonintuitive material—time as part of space, say, or proteins inventing themselves spontaneously, without direction—and the quantum leaps unusual minds have made: as J.B.S. Haldane once put it, “The universe is not only queerer than we suppose; it is queerer than we can suppose.” Mostly, though, Bryson renders clear the evolution of continental drift, atomic structure, singularity, the extinction of the dinosaur, and a mighty host of other subjects in self-contained chapters that can be taken at a bite, rather than read wholesale. He delivers the human-interest angle on the scientists, and he keeps the reader laughing and willing to forge ahead, even over their heads: the human body, for instance, harboring enough energy “to explode with the force of thirty very large hydrogen bombs, assuming you knew how to liberate it and really wished to make a point.”
Loads of good explaining, with reminders, time and again, of how much remains unknown, neatly putting the death of science into perspective.Pub Date: May 6, 2003
ISBN: 0-7679-0817-1
Page Count: 304
Publisher: Broadway
Review Posted Online: May 19, 2010
Kirkus Reviews Issue: April 1, 2003
BOOK TO SCREEN
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