A valiant effort to link medicine and injustice: thought-provoking, knowledgeable, and ripe for debate and further study.
A passionate exploration of world poverty, racism, injustice, and colonialism that draws a parallel to inflammation.
Marya is a physician, professor of internal medicine, and activist, and Patel is a professor of public affairs and nutrition and the author of the 2010 bestseller The Value of Nothing. In this collaboration, the authors explain that when tissues are damaged or threatened, our immune system sends cells and molecular messengers that attack invaders, repair damage, and restore the body to health. Sometimes, “the response doesn’t switch off, and the result is a chronic inflammatory state. When that happens, the body’s healing mechanism is transformed into a smoldering fire that creates ongoing harm.” We suffer more chronic inflammation as we get older, and external factors (environmental toxins, stress, malnutrition) are the leading causes. The authors are far from the first to stress chronic inflammation’s role in cancer, heart disease, diabetes, colitis, mental illness, dementia, and even aging, although they give it perhaps more credit than it deserves. They are rigorous scientists, so readers will learn a great deal as they describe human biological systems, focusing on the damage inflicted by inflammation but casting a wide thematic net. The chapter on the reproductive system eschews parallels with inflammation in favor of linking colonialism to the oppression of women. The obligatory how-to-fix-it conclusion will leave some readers scratching their heads. Having described a world of Orwellian awfulness, the authors propose not mass action but “deep medicine.” They write that individuals can be healthy “only when the entire community is also healthy…this is achievable only through social, economic, political, ecological, and cosmological spheres working in an integrated fashion for the benefit of all.” This may remind older readers of the ideals of universal harmony and spiritual growth that marked the 1960s, but the authors are persuasive in most of their arguments about the deleterious physical and mental effects of capitalism and colonialism.
A valiant effort to link medicine and injustice: thought-provoking, knowledgeable, and ripe for debate and further study.Pub Date: Aug. 3, 2021
ISBN: 978-0-374-60251-2
Page Count: 496
Publisher: Farrar, Straus and Giroux
Review Posted Online: June 1, 2021
Kirkus Reviews Issue: June 15, 2021
A short, smart analysis of perhaps the most famous passage in American history reveals its potency and unfulfilled promise.
Words that made a nation.
Isaacson is known for expansive biographies of great thinkers (and Elon Musk), but here he pens a succinct, stimulating commentary on the Founding Fathers’ ode to “life, liberty, and the pursuit of happiness.” His close reading of the Declaration of Independence’s second sentence, published to mark the 250th anniversary of the document’s adoption, doesn’t downplay its “moral contradiction.” Thomas Jefferson enslaved hundreds of people yet called slavery “a cruel war against human nature” in his first draft of the Declaration. All but 15 of the document’s 56 signers owned enslaved people. While the sentence in question asserted “all men are created equal” and possess “unalienable rights,” the Founders “consciously and intentionally” excluded women, Native Americans, and enslaved people. And yet the sentence is powerful, Isaacson writes, because it names a young nation’s “aspirations.” He mounts a solid defense of what ought to be shared goals, among them economic fairness, “moral compassion,” and a willingness to compromise. “Democracy depends on this,” he writes. Isaacson is excellent when explaining how Enlightenment intellectuals abroad influenced the founders. Benjamin Franklin, one of the Declaration’s “five-person drafting committee,” stayed in David Hume’s home for a month in the early 1770s, “discussing ideas of natural rights” with the Scottish philosopher. Also strong is Isaacson’s discussion of the “edits and tweaks” made to Jefferson’s draft. As recommended by Franklin and others, the changes were substantial, leaving Jefferson “distraught.” Franklin, who emerges as the book’s hero, helped establish municipal services, founded a library, and encouraged religious diversity—the kind of civic-mindedness that we could use more of today, Isaacson reminds us.
A short, smart analysis of perhaps the most famous passage in American history reveals its potency and unfulfilled promise.Pub Date: Nov. 18, 2025
ISBN: 9781982181314
Page Count: 80
Publisher: Simon & Schuster
Review Posted Online: Aug. 29, 2025
Kirkus Reviews Issue: Oct. 1, 2025
BOOK REVIEW
BOOK REVIEW
BOOK REVIEW
SEEN & HEARD
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...
A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.
Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.Pub Date: Jan. 19, 2016
ISBN: 978-0-8129-8840-6
Page Count: 248
Publisher: Random House
Review Posted Online: Sept. 29, 2015
Kirkus Reviews Issue: Oct. 15, 2015
PERSPECTIVES
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