A readable tale of medical achievement.
The story of the conquest of diabetes.
In roughly chronological order, Cooper and Ainsberg weave together the stories of the doctor who ran the first clinic for patients with diabetes, the scientists who first isolated insulin, a young woman among the first to receive the new drug and the research director of the pharmaceutical company that launched its production. The authors focus in turn on Dr. Frederick Allen, whose starvation diet could prolong patients’ lives but not save them; Frederick Banting, the insightful and persistent scientist whose work with the pancreases of dogs isolated insulin; Elizabeth Hughes, daughter of politician Charles Evans Hughes, whose influence enabled her to become one of the first diabetics to be saved by insulin; and George Clowes of Eli Lilly, who immediately saw insulin’s potential and figured out how to produce it commercially. Where research did not provide the necessary dialogue or even the dramatic incidents the authors needed, they have invented their own to enhance the narrative. The result is a work that sometimes reads like a novel, with the characters brought to life through their thoughts, remarks and physical gestures. The irascible Banting, whose hardships, jealousies and struggles with his colleagues seem endless, is perhaps the most fascinating. Young Elizabeth, seen primarily through excerpts from her letters, is a less-realized character than her parents. The authors seem especially intrigued by Elizabeth, however, puzzling over her later refusal to admit to having diabetes and her failure to include diabetes research in her philanthropic efforts. Caroline Cox’s The Fight To Survive: A Young Girl’s Struggle with Diabetes and the Discovery of Insulin (2009) offers a fuller profile of her but a briefer account of the insulin story.
A readable tale of medical achievement.Pub Date: Sept. 1, 2010
ISBN: 978-0-312-64870-1
Page Count: 304
Publisher: St. Martin's
Review Posted Online: June 1, 2010
Kirkus Reviews Issue: June 15, 2010
Dogged original research and superb narrative skills come together in this gripping account of pitiless evil.
Greed, depravity, and serial murder in 1920s Oklahoma.
During that time, enrolled members of the Osage Indian nation were among the wealthiest people per capita in the world. The rich oil fields beneath their reservation brought millions of dollars into the tribe annually, distributed to tribal members holding "headrights" that could not be bought or sold but only inherited. This vast wealth attracted the attention of unscrupulous whites who found ways to divert it to themselves by marrying Osage women or by having Osage declared legally incompetent so the whites could fleece them through the administration of their estates. For some, however, these deceptive tactics were not enough, and a plague of violent death—by shooting, poison, orchestrated automobile accident, and bombing—began to decimate the Osage in what they came to call the "Reign of Terror." Corrupt and incompetent law enforcement and judicial systems ensured that the perpetrators were never found or punished until the young J. Edgar Hoover saw cracking these cases as a means of burnishing the reputation of the newly professionalized FBI. Bestselling New Yorkerstaff writer Grann (The Devil and Sherlock Holmes: Tales of Murder, Madness, and Obsession, 2010, etc.) follows Special Agent Tom White and his assistants as they track the killers of one extended Osage family through a closed local culture of greed, bigotry, and lies in pursuit of protection for the survivors and justice for the dead. But he doesn't stop there; relying almost entirely on primary and unpublished sources, the author goes on to expose a web of conspiracy and corruption that extended far wider than even the FBI ever suspected. This page-turner surges forward with the pacing of a true-crime thriller, elevated by Grann's crisp and evocative prose and enhanced by dozens of period photographs.
Dogged original research and superb narrative skills come together in this gripping account of pitiless evil.Pub Date: April 18, 2017
ISBN: 978-0-385-53424-6
Page Count: 352
Publisher: Doubleday
Review Posted Online: Feb. 1, 2017
Kirkus Reviews Issue: Feb. 15, 2017
BOOK TO SCREEN
BOOK TO SCREEN
BOOK TO SCREEN
Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and...
A dense, absorbing investigation into the medical community's exploitation of a dying woman and her family's struggle to salvage truth and dignity decades later.
In a well-paced, vibrant narrative, Popular Science contributor and Culture Dish blogger Skloot (Creative Writing/Univ. of Memphis) demonstrates that for every human cell put under a microscope, a complex life story is inexorably attached, to which doctors, researchers and laboratories have often been woefully insensitive and unaccountable. In 1951, Henrietta Lacks, an African-American mother of five, was diagnosed with what proved to be a fatal form of cervical cancer. At Johns Hopkins, the doctors harvested cells from her cervix without her permission and distributed them to labs around the globe, where they were multiplied and used for a diverse array of treatments. Known as HeLa cells, they became one of the world's most ubiquitous sources for medical research of everything from hormones, steroids and vitamins to gene mapping, in vitro fertilization, even the polio vaccine—all without the knowledge, must less consent, of the Lacks family. Skloot spent a decade interviewing every relative of Lacks she could find, excavating difficult memories and long-simmering outrage that had lay dormant since their loved one's sorrowful demise. Equal parts intimate biography and brutal clinical reportage, Skloot's graceful narrative adeptly navigates the wrenching Lack family recollections and the sobering, overarching realities of poverty and pre–civil-rights racism. The author's style is matched by a methodical scientific rigor and manifest expertise in the field.
Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and Petri dish politics.Pub Date: Feb. 9, 2010
ISBN: 978-1-4000-5217-2
Page Count: 320
Publisher: Crown
Review Posted Online: Dec. 22, 2010
Kirkus Reviews Issue: Jan. 1, 2010
BOOK REVIEW
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