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ALLERGIC

OUR IRRITATED BODIES IN A CHANGING WORLD

An exhaustive and accessible report.

A holistic study of how allergies continue to bewilder medical science.

As a medical anthropologist, MacPhail’s subject matter is both professional and personal. In 1996, her father died suddenly of anaphylaxis after a bee sting. That event prompted the author to carry an EpiPen and to launch a research project examining the “puzzle of allergies.” In a deft three-part analysis, she probes the biological processes of allergens and the misconceptions surrounding them. She then examines the “confusing maze” of diagnosis and the causative theories on why allergies are proliferating, and she explores possible solutions and the progress medical science has made (outside of antihistamines) treating global allergy issues, including the development of promising new vaccines. MacPhail cites historical information from the early 1800s, when the first allergy was medically documented, and consistently attempts to nail down the ever shifting definitions of what allergies actually are, tackling the vexing question of origin with informed speculation. Whether it be the cumulative effects of environmental changes, industrial development, food additives, or genetic mutations, specific people seem more vulnerable to certain allergens. The author optimistically reflects on modern immunological advancements that have provided relief, and she presents a series of crisply rendered perspectives of people who cited severe allergies to airborne allergens, dust mites, or specific foods—all frustrated by the lack of a definitive cause or the unaffordability/unavailability of longer-term remedies. “In a capitalistic system,” she writes, “a patient is akin to a customer.” While the culprits responsible for the increases in allergic sufferers are debatable moving targets, MacPhail skillfully narrows down the possibilities and some of the solutions, although her contradictory advice on air purifiers may confuse readers seeking solace. Nonetheless, the author’s examination of the science of immunology from a social and cultural perspective will give readers plenty of relevant, thought-provoking information.

An exhaustive and accessible report.

Pub Date: May 30, 2023

ISBN: 9780593229194

Page Count: 368

Publisher: Random House

Review Posted Online: March 24, 2023

Kirkus Reviews Issue: April 15, 2023

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THE IMMORTAL LIFE OF HENRIETTA LACKS

Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and...

A dense, absorbing investigation into the medical community's exploitation of a dying woman and her family's struggle to salvage truth and dignity decades later.

In a well-paced, vibrant narrative, Popular Science contributor and Culture Dish blogger Skloot (Creative Writing/Univ. of Memphis) demonstrates that for every human cell put under a microscope, a complex life story is inexorably attached, to which doctors, researchers and laboratories have often been woefully insensitive and unaccountable. In 1951, Henrietta Lacks, an African-American mother of five, was diagnosed with what proved to be a fatal form of cervical cancer. At Johns Hopkins, the doctors harvested cells from her cervix without her permission and distributed them to labs around the globe, where they were multiplied and used for a diverse array of treatments. Known as HeLa cells, they became one of the world's most ubiquitous sources for medical research of everything from hormones, steroids and vitamins to gene mapping, in vitro fertilization, even the polio vaccine—all without the knowledge, must less consent, of the Lacks family. Skloot spent a decade interviewing every relative of Lacks she could find, excavating difficult memories and long-simmering outrage that had lay dormant since their loved one's sorrowful demise. Equal parts intimate biography and brutal clinical reportage, Skloot's graceful narrative adeptly navigates the wrenching Lack family recollections and the sobering, overarching realities of poverty and pre–civil-rights racism. The author's style is matched by a methodical scientific rigor and manifest expertise in the field.

Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and Petri dish politics.

Pub Date: Feb. 9, 2010

ISBN: 978-1-4000-5217-2

Page Count: 320

Publisher: Crown

Review Posted Online: Dec. 22, 2010

Kirkus Reviews Issue: Jan. 1, 2010

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F*CK IT, I'LL START TOMORROW

The lessons to draw are obvious: Smoke more dope, eat less meat. Like-minded readers will dig it.

The chef, rapper, and TV host serves up a blustery memoir with lashings of self-help.

“I’ve always had a sick confidence,” writes Bronson, ne Ariyan Arslani. The confidence, he adds, comes from numerous sources: being a New Yorker, and more specifically a New Yorker from Queens; being “short and fucking husky” and still game for a standoff on the basketball court; having strength, stamina, and seemingly no fear. All these things serve him well in the rough-and-tumble youth he describes, all stickball and steroids. Yet another confidence-builder: In the big city, you’ve got to sink or swim. “No one is just accepted—you have to fucking show that you’re able to roll,” he writes. In a narrative steeped in language that would make Lenny Bruce blush, Bronson recounts his sentimental education, schooled by immigrant Italian and Albanian family members and the mean streets, building habits good and bad. The virtue of those habits will depend on your take on modern mores. Bronson writes, for example, of “getting my dick pierced” down in the West Village, then grabbing a pizza and smoking weed. “I always smoke weed freely, always have and always will,” he writes. “I’ll just light a blunt anywhere.” Though he’s gone through the classic experiences of the latter-day stoner, flunking out and getting arrested numerous times, Bronson is a hard charger who’s not afraid to face nearly any challenge—especially, given his physique and genes, the necessity of losing weight: “If you’re husky, you’re always dieting in your mind,” he writes. Though vulgar and boastful, Bronson serves up a model that has plenty of good points, including his growing interest in nature, creativity, and the desire to “leave a legacy for everybody.”

The lessons to draw are obvious: Smoke more dope, eat less meat. Like-minded readers will dig it.

Pub Date: April 20, 2021

ISBN: 978-1-4197-4478-5

Page Count: 184

Publisher: Abrams

Review Posted Online: May 5, 2021

Kirkus Reviews Issue: June 1, 2021

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