Utterly timely and readable, if not terribly comforting in the midst of the current pandemic.
A geeky but fascinating exploration of the mathematics of things that go viral—not least of them viruses.
“If we want a better grasp of contagion, we need to account for its dynamic nature,” writes Kucharski, who does mathematical modeling of disease transmission at the London School of Hygiene & Tropical Medicine. He elaborates throughout: Contagion is constantly in motion as it courses through a population, finding its “susceptibles” and slowing down as the number of susceptibles declines. By the author’s capable account, the math works out pretty much the same whether applied to some negative force, such as a COVID-19 category virus or the concomitant financial crumbling that has surrounded it, or some positive force—e.g., a cultural innovation such as a pop song or dance move. Kucharski works his way through some key epidemiological ideas, including one advanced by the scientist who put it together that malaria was spread by mosquitos, earning him the Nobel Prize—although that scientist later protested that his larger achievement was formulating “general laws of epidemics.” These laws embody a mathematical formula that looks rather like an hourglass turned on its side, representing three key groups: the susceptible, the infectious, and the recovered. There are also the dead, of course, but they don’t move, as the dynamic model does. Kucharski takes his readers down provocative detours, such as the use of public-health models of disease transmission to examine how social networks figure in urban gun violence, with algorithms that take into account such things as “age gang affiliations, and prior arrests.” When things go viral, all kinds of interesting mathematical and real-world effects can happen, from stock market bubbles to horrific explosions of disease. Kucharski is there, calculator in hand, to suss it all out, and highly numerate readers will enjoy going along with the ride to guesstimate the R value of a contagion’s spread.
Utterly timely and readable, if not terribly comforting in the midst of the current pandemic.Pub Date: July 7, 2020
ISBN: 978-1-5416-7431-8
Page Count: 352
Publisher: Basic Books
Review Posted Online: April 28, 2020
Kirkus Reviews Issue: May 15, 2020
BOOK REVIEW
Alternately admiring and critical, unvarnished, and a closely detailed account of a troubled innovator.
A warts-and-all portrait of the famed techno-entrepreneur—and the warts are nearly beyond counting.
To call Elon Musk (b. 1971) “mercurial” is to undervalue the term; to call him a genius is incorrect. Instead, Musk has a gift for leveraging the genius of others in order to make things work. When they don’t, writes eminent biographer Isaacson, it’s because the notoriously headstrong Musk is so sure of himself that he charges ahead against the advice of others: “He does not like to share power.” In this sharp-edged biography, the author likens Musk to an earlier biographical subject, Steve Jobs. Given Musk’s recent political turn, born of the me-first libertarianism of the very rich, however, Henry Ford also comes to mind. What emerges clearly is that Musk, who may or may not have Asperger’s syndrome (“Empathy did not come naturally”), has nurtured several obsessions for years, apart from a passion for the letter X as both a brand and personal name. He firmly believes that “all requirements should be treated as recommendations”; that it is his destiny to make humankind a multi-planetary civilization through innovations in space travel; that government is generally an impediment and that “the thought police are gaining power”; and that “a maniacal sense of urgency” should guide his businesses. That need for speed has led to undeniable successes in beating schedules and competitors, but it has also wrought disaster: One of the most telling anecdotes in the book concerns Musk’s “demon mode” order to relocate thousands of Twitter servers from Sacramento to Portland at breakneck speed, which trashed big parts of the system for months. To judge by Isaacson’s account, that may have been by design, for Musk’s idea of creative destruction seems to mean mostly chaos.
Alternately admiring and critical, unvarnished, and a closely detailed account of a troubled innovator.Pub Date: Sept. 12, 2023
ISBN: 9781982181284
Page Count: 688
Publisher: Simon & Schuster
Review Posted Online: Sept. 12, 2023
Kirkus Reviews Issue: Oct. 15, 2023
BOOK REVIEW
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BOOK TO SCREEN
Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and...
A dense, absorbing investigation into the medical community's exploitation of a dying woman and her family's struggle to salvage truth and dignity decades later.
In a well-paced, vibrant narrative, Popular Science contributor and Culture Dish blogger Skloot (Creative Writing/Univ. of Memphis) demonstrates that for every human cell put under a microscope, a complex life story is inexorably attached, to which doctors, researchers and laboratories have often been woefully insensitive and unaccountable. In 1951, Henrietta Lacks, an African-American mother of five, was diagnosed with what proved to be a fatal form of cervical cancer. At Johns Hopkins, the doctors harvested cells from her cervix without her permission and distributed them to labs around the globe, where they were multiplied and used for a diverse array of treatments. Known as HeLa cells, they became one of the world's most ubiquitous sources for medical research of everything from hormones, steroids and vitamins to gene mapping, in vitro fertilization, even the polio vaccine—all without the knowledge, must less consent, of the Lacks family. Skloot spent a decade interviewing every relative of Lacks she could find, excavating difficult memories and long-simmering outrage that had lay dormant since their loved one's sorrowful demise. Equal parts intimate biography and brutal clinical reportage, Skloot's graceful narrative adeptly navigates the wrenching Lack family recollections and the sobering, overarching realities of poverty and pre–civil-rights racism. The author's style is matched by a methodical scientific rigor and manifest expertise in the field.
Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and Petri dish politics.Pub Date: Feb. 9, 2010
ISBN: 978-1-4000-5217-2
Page Count: 320
Publisher: Crown
Review Posted Online: Dec. 22, 2010
Kirkus Reviews Issue: Jan. 1, 2010
BOOK REVIEW
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