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EMBRYO CULTURE

MAKING BABIES IN THE TWENTY-FIRST CENTURY

No answers here, but lots of provocative questions amid sobs, sighs and odes to joy.

Everything you ever wanted to know about in vitro fertilization.

IVF is not easy. It’s not fun. And oh my, the invasion of privacy! But the desire to bear a child is unbelievably powerful, as first-time author Kohl testifies in this high-pitched, very personal narrative. She and her husband, like other infertile couples, devoted vast amounts of energy to scoping out fertility clinics by gut reaction, word of mouth and advertised success rates. No regulatory agencies set rules for this process. Because of federal prohibitions against embryo research, fertility clinics in America are private enterprises whose “research” consists mostly of learning by doing. After a woman has been hormonally primed to generate multiple ova ripe for removal and fertilization by her partner’s or a donor’s semen, the eggs are incubated. After a few days, those that look healthiest are inserted into the woman’s uterus, where it is hoped one or more will implant and develop to term. Since there is no way to predict which will implant, IVF often leads to multiple births. In Kohl’s case, her first baby was a single, and she subsequently bore twin girls. All are healthy, but the author rightly notes that multiple births pose risks to both mothers and offspring. She goes on to discuss ethical and religious attitudes towards IVF, egg and sperm donors and surrogates. She also addresses the particularly thorny subject of frozen embryos, already the source of bitter courtroom battles involving knotty legal issues. Good liberal and believer in stem-cell research that she is, the author confesses she’s not so sure she wants to give up her frozen spare embryos; after her experiences with IVF, she can’t help but see them as all-too-real potential sibs for her girls.

No answers here, but lots of provocative questions amid sobs, sighs and odes to joy.

Pub Date: Aug. 1, 2007

ISBN: 978-0-374-14757-0

Page Count: 208

Publisher: Sarah Crichton/Farrar, Straus and Giroux

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: June 1, 2007

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THE IMMORTAL LIFE OF HENRIETTA LACKS

Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and...

A dense, absorbing investigation into the medical community's exploitation of a dying woman and her family's struggle to salvage truth and dignity decades later.

In a well-paced, vibrant narrative, Popular Science contributor and Culture Dish blogger Skloot (Creative Writing/Univ. of Memphis) demonstrates that for every human cell put under a microscope, a complex life story is inexorably attached, to which doctors, researchers and laboratories have often been woefully insensitive and unaccountable. In 1951, Henrietta Lacks, an African-American mother of five, was diagnosed with what proved to be a fatal form of cervical cancer. At Johns Hopkins, the doctors harvested cells from her cervix without her permission and distributed them to labs around the globe, where they were multiplied and used for a diverse array of treatments. Known as HeLa cells, they became one of the world's most ubiquitous sources for medical research of everything from hormones, steroids and vitamins to gene mapping, in vitro fertilization, even the polio vaccine—all without the knowledge, must less consent, of the Lacks family. Skloot spent a decade interviewing every relative of Lacks she could find, excavating difficult memories and long-simmering outrage that had lay dormant since their loved one's sorrowful demise. Equal parts intimate biography and brutal clinical reportage, Skloot's graceful narrative adeptly navigates the wrenching Lack family recollections and the sobering, overarching realities of poverty and pre–civil-rights racism. The author's style is matched by a methodical scientific rigor and manifest expertise in the field.

Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and Petri dish politics.

Pub Date: Feb. 9, 2010

ISBN: 978-1-4000-5217-2

Page Count: 320

Publisher: Crown

Review Posted Online: Dec. 22, 2010

Kirkus Reviews Issue: Jan. 1, 2010

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WHY WE SWIM

An absorbing, wide-ranging story of humans’ relationship with the water.

A study of swimming as sport, survival method, basis for community, and route to physical and mental well-being.

For Bay Area writer Tsui (American Chinatown: A People's History of Five Neighborhoods, 2009), swimming is in her blood. As she recounts, her parents met in a Hong Kong swimming pool, and she often visited the beach as a child and competed on a swim team in high school. Midway through the engaging narrative, the author explains how she rejoined the team at age 40, just as her 6-year-old was signing up for the first time. Chronicling her interviews with scientists and swimmers alike, Tsui notes the many health benefits of swimming, some of which are mental. Swimmers often achieve the “flow” state and get their best ideas while in the water. Her travels took her from the California coast, where she dove for abalone and swam from Alcatraz back to San Francisco, to Tokyo, where she heard about the “samurai swimming” martial arts tradition. In Iceland, she met Guðlaugur Friðþórsson, a local celebrity who, in 1984, survived six hours in a winter sea after his fishing vessel capsized, earning him the nickname “the human seal.” Although humans are generally adapted to life on land, the author discovered that some have extra advantages in the water. The Bajau people of Indonesia, for instance, can do 10-minute free dives while hunting because their spleens are 50% larger than average. For most, though, it’s simply a matter of practice. Tsui discussed swimming with Dara Torres, who became the oldest Olympic swimmer at age 41, and swam with Kim Chambers, one of the few people to complete the daunting Oceans Seven marathon swim challenge. Drawing on personal experience, history, biology, and social science, the author conveys the appeal of “an unflinching giving-over to an element” and makes a convincing case for broader access to swimming education (372,000 people still drown annually).

An absorbing, wide-ranging story of humans’ relationship with the water.

Pub Date: April 14, 2020

ISBN: 978-1-61620-786-1

Page Count: 288

Publisher: Algonquin

Review Posted Online: Jan. 4, 2020

Kirkus Reviews Issue: Feb. 1, 2020

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