A clear and readable exposition of the interface between genetics and anthropology, enlivened by a wry sense of humor.

THE SEVEN DAUGHTERS OF EVE

THE SCIENCE THAT REVEALS OUR GENETIC ANCESTRY

A British geneticist details the contributions of his discipline to anthropology.

Perhaps the most startling breakthrough of genetic science is the confirmation that we are all descended from a very small number of prehistoric individuals. Sykes (Molecular Medicine/Oxford) has been examining DNA from fossil animals and humans, and from their modern descendents, since the 1980s. At an early stage, he and his colleagues recognized that the relationships of far-flung modern populations will be recorded in the sequence of their DNA—particularly mitochondrial DNA, which is inherited exclusively from one’s mother, and which mutates at a slow but steady rate. Armed with blood samples from across the Pacific, he traced the Polynesians to their origins in the neighborhood of Taiwan. His investigations of European DNA appear to eliminate the hypothesis that modern humans are in part descended from Neanderthals. Controversy arose when Sykes’s research contradicted the widely received theory that the indigenous hunter-gatherer population of Europe was largely replaced by an influx of farmers from the Middle East in the early Neolithic period. Mitochondrial DNA indicated that instead of being wiped out by invading farmers, the natives adopted the practice of agriculture from the easterners; the culture changed, not the population. The anthropological establishment at first denied the validity of his methods, but independent lines of DNA evidence confirmed his results, indicating that the Neolithic influx contributed only about 20 percent of the modern European genetic heritage. Most recently, Sykes has determined that the vast majority of Europeans are descended from seven prehistoric women—whom he names and imaginatively describes in the final chapters of this entertaining book. These fictional re-creations give a useful sense of the complexity of early human society.

A clear and readable exposition of the interface between genetics and anthropology, enlivened by a wry sense of humor.

Pub Date: July 9, 2001

ISBN: 0-393-02018-5

Page Count: 320

Publisher: Norton

Review Posted Online: May 20, 2010

Kirkus Reviews Issue: May 15, 2001

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A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...

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WHEN BREATH BECOMES AIR

A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.

Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.

Pub Date: Jan. 19, 2016

ISBN: 978-0-8129-8840-6

Page Count: 248

Publisher: Random House

Review Posted Online: Sept. 30, 2015

Kirkus Reviews Issue: Oct. 15, 2015

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This moving, potent testament might have been titled “Black Lives Matter.” Or: “An American Tragedy.”

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BETWEEN THE WORLD AND ME

NOTES ON THE FIRST 150 YEARS IN AMERICA

The powerful story of a father’s past and a son’s future.

Atlantic senior writer Coates (The Beautiful Struggle: A Father, Two Sons, and an Unlikely Road to Manhood, 2008) offers this eloquent memoir as a letter to his teenage son, bearing witness to his own experiences and conveying passionate hopes for his son’s life. “I am wounded,” he writes. “I am marked by old codes, which shielded me in one world and then chained me in the next.” Coates grew up in the tough neighborhood of West Baltimore, beaten into obedience by his father. “I was a capable boy, intelligent and well-liked,” he remembers, “but powerfully afraid.” His life changed dramatically at Howard University, where his father taught and from which several siblings graduated. Howard, he writes, “had always been one of the most critical gathering posts for black people.” He calls it The Mecca, and its faculty and his fellow students expanded his horizons, helping him to understand “that the black world was its own thing, more than a photo-negative of the people who believe they are white.” Coates refers repeatedly to whites’ insistence on their exclusive racial identity; he realizes now “that nothing so essentialist as race” divides people, but rather “the actual injury done by people intent on naming us, intent on believing that what they have named matters more than anything we could ever actually do.” After he married, the author’s world widened again in New York, and later in Paris, where he finally felt extricated from white America’s exploitative, consumerist dreams. He came to understand that “race” does not fully explain “the breach between the world and me,” yet race exerts a crucial force, and young blacks like his son are vulnerable and endangered by “majoritarian bandits.” Coates desperately wants his son to be able to live “apart from fear—even apart from me.”

This moving, potent testament might have been titled “Black Lives Matter.” Or: “An American Tragedy.”

Pub Date: July 8, 2015

ISBN: 978-0-8129-9354-7

Page Count: 176

Publisher: Spiegel & Grau

Review Posted Online: May 6, 2015

Kirkus Reviews Issue: July 1, 2015

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