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MOTHER BRAIN

HOW NEUROSCIENCE IS REWRITING THE STORY OF PARENTHOOD

Useful, well-informed encouragement for new and prospective parents.

How parenting affects body and mind.

Conaboy, a journalist specializing in health issues, makes an engaging book debut with an informative, well-researched look at the physical and psychological changes caused by engaging in “the life-supporting practice of mothering.” Drawing on interviews with parents, scientists, and medical practitioners; examining abundant research; and reflecting on her own experiences as the mother of two sons, the author depicts motherhood as “a distinct developmental stage with long-lasting effects, in which each of the body’s systems thought to regulate social behavior, emotion, and immune responses” are dramatically affected. Noting the dearth of scientific studies about parents who are not “straight, cisgender people who share DNA with their child,” Conaboy focuses largely on birth mothers while also reporting on the experiences of fathers and other relatives involved in caregiving. In a historical and cultural overview of assumptions about motherhood, she underscores the social, political, and religious forces that gave rise to “the fallacy of the maternal instinct,” which has left some women feeling inadequate and guilty. She roundly debunks this notion, taken as scientific fact by lawmakers who want to limit reproductive rights and maternity benefits by arguing that motherhood is women’s destiny and that mothers are innately constituted as caregivers. Conaboy shares research in neurobiology and endocrinology that has revealed complex ways that pregnancy, birth, and caregiving reorganize the brain, “altering the neural feedback loops that dictate how we react to the world around us, how we read and respond to other people, and how we regulate our own emotions.” These changes occur, in varying degrees, in both men and women. The author deftly translates scientific studies—by neurobiologists, anthropologists, primatologists, psychologists, and endocrinologists, among others—into accessible prose that speaks to needs and anxieties that many parents share. Adapting to motherhood, she asserts, is “a bodily challenge and a logistical challenge” that lasts a lifetime.

Useful, well-informed encouragement for new and prospective parents.

Pub Date: Sept. 13, 2022

ISBN: 978-1-250-76228-3

Page Count: 368

Publisher: Henry Holt

Review Posted Online: June 20, 2022

Kirkus Reviews Issue: July 15, 2022

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THE GREATEST SENTENCE EVER WRITTEN

A short, smart analysis of perhaps the most famous passage in American history reveals its potency and unfulfilled promise.

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Words that made a nation.

Isaacson is known for expansive biographies of great thinkers (and Elon Musk), but here he pens a succinct, stimulating commentary on the Founding Fathers’ ode to “life, liberty, and the pursuit of happiness.” His close reading of the Declaration of Independence’s second sentence, published to mark the 250th anniversary of the document’s adoption, doesn’t downplay its “moral contradiction.” Thomas Jefferson enslaved hundreds of people yet called slavery “a cruel war against human nature” in his first draft of the Declaration. All but 15 of the document’s 56 signers owned enslaved people. While the sentence in question asserted “all men are created equal” and possess “unalienable rights,” the Founders “consciously and intentionally” excluded women, Native Americans, and enslaved people. And yet the sentence is powerful, Isaacson writes, because it names a young nation’s “aspirations.” He mounts a solid defense of what ought to be shared goals, among them economic fairness, “moral compassion,” and a willingness to compromise. “Democracy depends on this,” he writes. Isaacson is excellent when explaining how Enlightenment intellectuals abroad influenced the founders. Benjamin Franklin, one of the Declaration’s “five-person drafting committee,” stayed in David Hume’s home for a month in the early 1770s, “discussing ideas of natural rights” with the Scottish philosopher. Also strong is Isaacson’s discussion of the “edits and tweaks” made to Jefferson’s draft. As recommended by Franklin and others, the changes were substantial, leaving Jefferson “distraught.” Franklin, who emerges as the book’s hero, helped establish municipal services, founded a library, and encouraged religious diversity—the kind of civic-mindedness that we could use more of today, Isaacson reminds us.

A short, smart analysis of perhaps the most famous passage in American history reveals its potency and unfulfilled promise.

Pub Date: Nov. 18, 2025

ISBN: 9781982181314

Page Count: 80

Publisher: Simon & Schuster

Review Posted Online: Aug. 29, 2025

Kirkus Reviews Issue: Oct. 1, 2025

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WHEN BREATH BECOMES AIR

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...

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A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.

Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.

Pub Date: Jan. 19, 2016

ISBN: 978-0-8129-8840-6

Page Count: 248

Publisher: Random House

Review Posted Online: Sept. 29, 2015

Kirkus Reviews Issue: Oct. 15, 2015

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