A readable, provocative look at biological tinkering that will doubtless shape the future, whether we like it or not.
Lucid study of recent efforts to alter the human gene to end hereditary diseases, a project fraught with ethical and medical implications.
Kirksey, an anthropologist who is often called upon to speak to humanistic, rather than strictly biological, views of human nature, explores a most human problem: the use of the new CRISPR technology to alter genes to remove undesirable features. “CRISPR is an enzyme that produces targeted mutagenesis,” he writes. “In other words, CRISPR generates mutants.” These mutants are not yet at the level of the famed X-Men, though they touch on a point in common. As Kirksey observes, the X-Men series “was created by two American Jewish men in 1963 as a parable about civil rights.” And what of the civil rights of the gene-edited babies produced recently in a Chinese laboratory? They have been carefully hidden away, for “the families desperately wanted to protect the identity of their children to prevent discriminatory treatment by society.” Kirksey’s primary narrative follows Jiankui He, the Chinese scientist responsible for the in vitro gene-edited procedure that produced a set of twins. Dr. He, a brilliant man who raised himself out of poverty through sheer effort, may have started with the best of intentions, but the gene-editing enterprise quickly became a profit center snapped up by excited corporations. Editing, writes the author, may not be the best metaphor: “CRISPR is more like a tiny Reaper drone that can produce targeted damage to DNA,” sometimes hitting precisely and sometimes inadvertently destroying good cells on either side. Whatever the case, scientists are already looking at eliminating existing mutations, “from primordial dwarfism to obscure conditions like CAMRQ (cerebellar ataxia, intellectual disability, and dysequilibrium syndrome),” a business without visible end and, of course, available first to those with the greatest financial resources.
A readable, provocative look at biological tinkering that will doubtless shape the future, whether we like it or not.Pub Date: Nov. 10, 2020
ISBN: 978-1-250-26535-7
Page Count: 304
Publisher: St. Martin's
Review Posted Online: Sept. 28, 2020
Kirkus Reviews Issue: Oct. 15, 2020
A virtuoso performance and an ode to an undervalued medium created by two talented artists.
The veteran actor, comedian, and banjo player teams up with the acclaimed illustrator to create a unique book of cartoons that communicates their personalities.
Martin, also a prolific author, has always been intrigued by the cartoons strewn throughout the pages of the New Yorker. So when he was presented with the opportunity to work with Bliss, who has been a staff cartoonist at the magazine since 1997, he seized the moment. “The idea of a one-panel image with or without a caption mystified me,” he writes. “I felt like, yeah, sometimes I’m funny, but there are these other weird freaks who are actually funny.” Once the duo agreed to work together, they established their creative process, which consisted of working forward and backward: “Forwards was me conceiving of several cartoon images and captions, and Harry would select his favorites; backwards was Harry sending me sketched or fully drawn cartoons for dialogue or banners.” Sometimes, he writes, “the perfect joke occurs two seconds before deadline.” There are several cartoons depicting this method, including a humorous multipanel piece highlighting their first meeting called “They Meet,” in which Martin thinks to himself, “He’ll never be able to translate my delicate and finely honed droll notions.” In the next panel, Bliss thinks, “I’m sure he won’t understand that the comic art form is way more subtle than his blunt-force humor.” The team collaborated for a year and created 150 cartoons featuring an array of topics, “from dogs and cats to outer space and art museums.” A witty creation of a bovine family sitting down to a gourmet meal and one of Dumbo getting his comeuppance highlight the duo’s comedic talent. What also makes this project successful is the team’s keen understanding of human behavior as viewed through their unconventional comedic minds.
A virtuoso performance and an ode to an undervalued medium created by two talented artists.Pub Date: Nov. 17, 2020
ISBN: 978-1-250-26289-9
Page Count: 272
Publisher: Celadon Books
Review Posted Online: Aug. 30, 2020
Kirkus Reviews Issue: Sept. 15, 2020
PERSPECTIVES
A football star’s bracing account of his battle for racial equality—and how powerful forces arrayed against him.
A principled athlete strives for social justice.
Kaepernick forthrightly details the activism that earned him global renown but cost him his NFL career. In 2016, the San Francisco 49ers quarterback “was filled with disgust” after police shootings of fellow Black men in several American cities. Before a preseason game, he made a spontaneous decision: “It hit me in that moment that I should find a seat” during the national anthem. He did the same at two more games before reporters noticed. Kaepernick will forever be associated with “taking a knee” during the anthem, but he credits Eric Reid—a teammate who agreed with Kaepernick’s message—for suggesting that they kneel together during subsequent anthems. The protest changed everything for Kaepernick. President Trump vilified him. Kaepernick and his wife received death threats. And though he’d taken the 49ers to a Super Bowl, no teams would sign him. He will likely make news for his take on Jay-Z, whose lucrative partnership with the NFL was criticized as an attempt to launder the league’s reputation. Visiting Africa, where Kaepernick learns about “African leaders who willingly sold their own people to the enslavers,” he “couldn’t help but to think about Jay-Z and the NFL.” In opening chapters, Kaepernick recalls suffering traumatic racial abuse as a child. Being in “white spaces”—he was adopted by white parents—placed him “under a microscope every minute of every day.” He isn’t always nuanced, depicting some people he disagrees with as cartoonishly clueless. But his writing about how college and pro teams “lied” to him about injuries underlines his “feeling of being a disposable commodity.” A decade has passed since Kaepernick played in the NFL, but he stays fit in case “a team needing a QB” calls.
A football star’s bracing account of his battle for racial equality—and how powerful forces arrayed against him.Pub Date: Sept. 15, 2026
ISBN: 9781538777879
Page Count: 288
Publisher: Legacy Lit/Hachette
Review Posted Online: June 15, 2026
Kirkus Reviews Issue: July 15, 2026
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