A blistering, persuasive critique of the harms done when drug companies hide the truth about their drugs.
A family physician and Harvard Medical School lecturer exposes the sordid tactics big pharma uses to jack up drug prices and con doctors about the facts they need to provide good care.
Abramson makes a powerful case that, over the past 40 years, profiteering drug companies have played an outsized role in two crises: the soaring costs of health care and America’s plunging “healthy life expectancy,” ranked 68th in the world in 2019. Linking the problem to a corporate shift to chasing profitability untethered from social responsibility, the author shows how corporations have hijacked sources of information doctors once could trust, such as medical journals, educational conferences, and lectures. The corruption began in the 1990s, when drug companies took control of clinical trials from academic medical centers; 6 out of 7 trials are now funded commercially by sponsors who have no obligation to show their data to medical journals. In an especially alarming chapter, Abramson shows how repeated changes in insulin have made it vastly more expensive for people with diabetes with little—if any—benefit. Companies have also withheld or manipulated facts about statins and popular drugs like Trulicity and Humira, which costs $78,000 per year. “Humira became by far the best-selling drug in the United States,” writes the author, “despite the fact that the manufacturer’s own study showed that it was no more effective as a first-line therapy for rheumatoid arthritis than methotrexate, which costs 99.5 percent less than Humira.” Abramson proposes worthy long-term solutions to the crisis, such as transparency about clinical trial results. But this book, the best on prescription drugs since Katherine Eban’s Bottle of Lies (2019), should also have high short-term value for patients, whom it might embolden to question their doctors more aggressively about whether there’s an equally effective substitute for a drug with a sky-high price tag.
A blistering, persuasive critique of the harms done when drug companies hide the truth about their drugs.Pub Date: Feb. 8, 2022
ISBN: 978-1-328-95781-8
Page Count: 336
Publisher: Mariner Books
Review Posted Online: Dec. 9, 2021
Kirkus Reviews Issue: Jan. 1, 2022
A quirky wonder of a book.
A Peabody Award–winning NPR science reporter chronicles the life of a turn-of-the-century scientist and how her quest led to significant revelations about the meaning of order, chaos, and her own existence.
Miller began doing research on David Starr Jordan (1851-1931) to understand how he had managed to carry on after the 1906 San Francisco earthquake destroyed his work. A taxonomist who is credited with discovering “a full fifth of fish known to man in his day,” Jordan had amassed an unparalleled collection of ichthyological specimens. Gathering up all the fish he could save, Jordan sewed the nameplates that had been on the destroyed jars directly onto the fish. His perseverance intrigued the author, who also discusses the struggles she underwent after her affair with a woman ended a heterosexual relationship. Born into an upstate New York farm family, Jordan attended Cornell and then became an itinerant scholar and field researcher until he landed at Indiana University, where his first ichthyological collection was destroyed by lightning. In between this catastrophe and others involving family members’ deaths, he reconstructed his collection. Later, he was appointed as the founding president of Stanford, where he evolved into a Machiavellian figure who trampled on colleagues and sang the praises of eugenics. Miller concludes that Jordan displayed the characteristics of someone who relied on “positive illusions” to rebound from disaster and that his stand on eugenics came from a belief in “a divine hierarchy from bacteria to humans that point[ed]…toward better.” Considering recent research that negates biological hierarchies, the author then suggests that Jordan’s beloved taxonomic category—fish—does not exist. Part biography, part science report, and part meditation on how the chaos that caused Miller’s existential misery could also bring self-acceptance and a loving wife, this unique book is an ingenious celebration of diversity and the mysterious order that underlies all existence.
A quirky wonder of a book.Pub Date: April 14, 2020
ISBN: 978-1-5011-6027-1
Page Count: 224
Publisher: Simon & Schuster
Review Posted Online: Jan. 1, 2020
Kirkus Reviews Issue: Feb. 1, 2020
BOOK REVIEW
Welcome reading for anyone concerned with real rigged elections.
Tired of the lies about the 2020 election? Buckle up: Trump is just warming up, and his allies may be getting craftier.
“This is not a book about January 6, 2021. It is a book about January 6, 2025,” write legal scholars Lessig and Seligman. We are lucky, Lessig suggests, that John Eastman and his fellow plotters “picked the dumbest possible strategy for pursuing what we feared they were trying to accomplish”: namely, trying to convince Mike Pence that he had the constitutional authority to refuse to certify the results by which Joe Biden won the presidency. One might argue that the second dumbest strategy was to send an army of fascist goons to the Capitol to try to enforce Eastman’s argument. However, Lessig and Seligman argue, there are holes in the Constitution wide enough to drive a burning dumpster through, and they might allow an interested party to falsely claim victory in a closely contested race and win the election. The authors presume that any such gaming-the-system effort will come from MAGA Republicans, though they add that a Democrat could easily use the same tactics. Readers may need a law degree to follow some of the arguments, but others are quite accessible. One argument that Lessig has been mounting for some time, for instance, is that the winner-take-all method employed by most states for electoral votes needs to be replaced with an apportionment system so that the Electoral College count will align with the popular vote. On that score, the authors warn, the prospect of rogue electors—or more, rogue governors who control those electors—is very real, and numerous other threats could enable someone smarter than the last bunch to mount “a cataclysmic attack on our democracy.”
Welcome reading for anyone concerned with real rigged elections.Pub Date: Feb. 13, 2024
ISBN: 9780300270792
Page Count: 176
Publisher: Yale Univ.
Review Posted Online: Dec. 6, 2023
Kirkus Reviews Issue: Jan. 1, 2024
© Copyright 2026 Kirkus Media LLC. All Rights Reserved.
Follow
Popular in this Genre
We can’t wait for you to join Kirkus!
It’s free and takes less than 10 seconds!
Already have an account? Log in.
OR
Sign in with GoogleTrouble signing in? Retrieve credentials.
Welcome Back!
OR
Sign in with GoogleTrouble signing in? Retrieve credentials.
