A far-fetched but often fun SF thriller.
A geneticist uncovers a universal, hardwired gene that determines the moment of one’s death in Thomas’ SF novel.
In the high-tech hub of Boston, Helix Innovations is a cutting-edge bio-medical giant researching the predictive genetic foundations of dire maladies. One of their young shining-star scientists, Dr. Emily Harper (who has a background in computer hacking) makes a shocking discovery: the “terminal gene,” sometimes called a “kill switch.” It seems every living organism possesses this, a pre-determined biological timer that unerringly forecasts exactly when that living thing will die. Such powerful knowledge applied by unscrupulous business interests and authorities is a frightening prospect: “The terminal gene had the potential to redefine medicine, providing insights into deadly diseases, or it might disrupt society, giving governments and corporations the power to exploit mortality...Would the government weaponize it, sorting citizens by their expiration dates?” Straightaway, Emily begins to receive threatening messages warning her to keep quiet and cooperate, or else. The danger seems to originate from a secret group called Chronos, which is already setting itself up to control the terminal gene and actively scheming to find a way to “reset” it. A mysterious person (or persons) known only as “Q” is also involved, though whether they are friend or foe is unknown. Emily’s apartment is ransacked, and the young scientist finds herself locked out of security protocols. This is too much for Emily’s live-in fiancé, Tyler, an ex-soldier with dormant-but-deadly combat skills. He and Emily zero in on unfriendly Helix CEO James Kessler as a likely source of harassment. But as paranoia escalates, it seems nobody can be trusted—not cherished academic mentors, Tyler’s former military associates, or a mysteriously reappearing Boston beat cop. Even worse, carefully concealed terminal-gene data indicates the approach of a mass-extinction event.
Some readers may find the terminal-gene concept to be less like a plot device from one of Michael Crichton’s just-on-the-edge-of-plausible thrillers and more like something bubbled up from the surrealistic imagination of Jorge Luis Borges (or early-1950s horror comic books). The concept is rather akin to a pin-cushioned Voodoo doll or a monkey’s paw that dictates one’s fate paranormally (death will come, no matter what ones does to prepare for or prevent it) rather than scientifically, though quite late in the action is there is some doubletalk about retroviruses and the like. Curiously, the story remains Boston-centric, even as news spreads of the doomsday discovery—the reactions from Washington, D.C., Wall Street, and the world in general feel curiously marginal. Readers able to suspend their disbelief will be left with an agreeable beach (or possibly hospital ward) read. It is only in the home stretch that the author addresses the philosophical conundrum, “Is it possible to reconcile human free will with a universe ruled by deterministic laws of nature?” before getting back to the action-heavy business of skulking through intranet firewalls and sneaking into besieged CRISPR labs (it is amusing how Emily, a celebrity whistleblower, can go unnoticed in a Beantown roiled by anti-Helix protests). One need not be a geneticist to diagnose the likelihood of sequels germinating.
A far-fetched but often fun SF thriller.Pub Date: Dec. 1, 2025
ISBN: 9798999838643
Page Count: 311
Publisher: Self
Review Posted Online: Dec. 14, 2025
Kirkus Reviews Issue: Feb. 1, 2026
Review Program: Kirkus Indie
Suspenseful, frightening, and sometimes poignant—provided the reader has a generously willing suspension of disbelief.
A man walks out of a bar and his life becomes a kaleidoscope of altered states in this science-fiction thriller.
Crouch opens on a family in a warm, resonant domestic moment with three well-developed characters. At home in Chicago’s Logan Square, Jason Dessen dices an onion while his wife, Daniela, sips wine and chats on the phone. Their son, Charlie, an appealing 15-year-old, sketches on a pad. Still, an undertone of regret hovers over the couple, a preoccupation with roads not taken, a theme the book will literally explore, in multifarious ways. To start, both Jason and Daniela abandoned careers that might have soared, Jason as a physicist, Daniela as an artist. When Charlie was born, he suffered a major illness. Jason was forced to abandon promising research to teach undergraduates at a small college. Daniela turned from having gallery shows to teaching private art lessons to middle school students. On this bracing October evening, Jason visits a local bar to pay homage to Ryan Holder, a former college roommate who just received a major award for his work in neuroscience, an honor that rankles Jason, who, Ryan says, gave up on his career. Smarting from the comment, Jason suffers “a sucker punch” as he heads home that leaves him “standing on the precipice.” From behind Jason, a man with a “ghost white” face, “red, pursed lips," and "horrifying eyes” points a gun at Jason and forces him to drive an SUV, following preset navigational directions. At their destination, the abductor forces Jason to strip naked, beats him, then leads him into a vast, abandoned power plant. Here, Jason meets men and women who insist they want to help him. Attempting to escape, Jason opens a door that leads him into a series of dark, strange, yet eerily familiar encounters that sometimes strain credibility, especially in the tale's final moments.
Suspenseful, frightening, and sometimes poignant—provided the reader has a generously willing suspension of disbelief.Pub Date: July 26, 2016
ISBN: 978-1-101-90422-0
Page Count: 352
Publisher: Crown
Review Posted Online: May 3, 2016
Kirkus Reviews Issue: May 15, 2016
PROFILES
BOOK TO SCREEN
BOOK TO SCREEN
An unforgettable story of survival and the power of friendship—nothing short of a science-fiction masterwork.
Weir’s latest is a page-turning interstellar thrill ride that follows a junior high school teacher–turned–reluctant astronaut at the center of a desperate mission to save humankind from a looming extinction event.
Ryland Grace was a once-promising molecular biologist who wrote a controversial academic paper contesting the assumption that life requires liquid water. Now disgraced, he works as a junior high science teacher in San Francisco. His previous theories, however, make him the perfect researcher for a multinational task force that's trying to understand how and why the sun is suddenly dimming at an alarming rate. A barely detectable line of light that rises from the sun’s north pole and curves toward Venus is inexplicably draining the star of power. According to scientists, an “instant ice age” is all but inevitable within a few decades. All the other stars in proximity to the sun seem to be suffering with the same affliction—except Tau Ceti. An unwilling last-minute replacement as part of a three-person mission heading to Tau Ceti in hopes of finding an answer, Ryland finds himself awakening from an induced coma on the spaceship with two dead crewmates and a spotty memory. With time running out for humankind, he discovers an alien spacecraft in the vicinity of his ship with a strange traveler on a similar quest. Although hard scientific speculation fuels the storyline, the real power lies in the many jaw-dropping plot twists, the relentless tension, and the extraordinary dynamic between Ryland and the alien (whom he nicknames Rocky because of its carapace of oxidized minerals and metallic alloy bones). Readers may find themselves consuming this emotionally intense and thematically profound novel in one stay-up-all-night-until-your-eyes-bleed sitting.
An unforgettable story of survival and the power of friendship—nothing short of a science-fiction masterwork.Pub Date: May 4, 2021
ISBN: 978-0-593-13520-4
Page Count: 496
Publisher: Ballantine
Review Posted Online: Feb. 9, 2021
Kirkus Reviews Issue: March 1, 2021
SEEN & HEARD
SEEN & HEARD
SEEN & HEARD
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