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THE BIOLOGY OF DESIRE

WHY ADDICTION IS NOT A DISEASE

A thought-provoking, industry-minded, and polarizing perspective on the neurocircuitry of human desire and compulsion.

An argument against classifying addiction as a chronic “brain disease.”

Armed with scientific data and plenty of case studies, developmental neuroscientist and former addict Lewis (Memoirs of an Addicted Brain: A Neuroscientist Examines His Former Life on Drugs, 2012) enters the ongoing addiction nomenclature debate with an intellectually authoritative yet controversial declaration that substance and behavioral dependencies are swiftly and deeply learned via the “neural circuitry of desire.” The author blames the medical community for developing a disease-model juggernaut derived primarily from clinical data rather than biological and psychological research on brain changes and altered synapses. Lewis believes this conceptualization pegged the affliction as a disease instead of what he deems a “developmental cascade and a detrimental result of habitual behaviors.” As increasing numbers of medical communities have embraced the addiction model this way, he writes, treatment methodologies often become ineffective as well. Lewis further criticizes the Alcoholics Anonymous strategy and its emphasis on an addict’s ability to surrender to their “powerlessness” over a compulsion rather than promoting personal empowerment toward self-sustainability. Once past a somewhat overly clinical neuroscientific discussion on the brain’s plasticity, Lewis introduces biographical testimonies of Americans struggling with addiction that both humanize and reinforce his standpoint. Awash in the separate throes of heroin, methamphetamine, opiates, alcohol, and binge-eating compulsions, the cases are complemented with uplifting updates on their sobriety efforts, which the author prefers to call a “developmental journey” toward recovery. Lewis’ statement that addiction is “uncannily normal” likely stems from his experiences as a former narcotic addict who overcame a decadelong drug habit at age 30. While definite fodder for debate, the author remains firm in his belief that in order to fully process the addiction spectrum, we must “gaze directly at the point where experience and biology meet.”

A thought-provoking, industry-minded, and polarizing perspective on the neurocircuitry of human desire and compulsion.

Pub Date: July 14, 2015

ISBN: 978-1-61039-437-6

Page Count: 256

Publisher: PublicAffairs

Review Posted Online: May 13, 2015

Kirkus Reviews Issue: June 1, 2015

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MASTERY

Readers unfamiliar with the anecdotal material Greene presents may find interesting avenues to pursue, but they should...

Greene (The 33 Strategies of War, 2007, etc.) believes that genius can be learned if we pay attention and reject social conformity.

The author suggests that our emergence as a species with stereoscopic, frontal vision and sophisticated hand-eye coordination gave us an advantage over earlier humans and primates because it allowed us to contemplate a situation and ponder alternatives for action. This, along with the advantages conferred by mirror neurons, which allow us to intuit what others may be thinking, contributed to our ability to learn, pass on inventions to future generations and improve our problem-solving ability. Throughout most of human history, we were hunter-gatherers, and our brains are engineered accordingly. The author has a jaundiced view of our modern technological society, which, he writes, encourages quick, rash judgments. We fail to spend the time needed to develop thorough mastery of a subject. Greene writes that every human is “born unique,” with specific potential that we can develop if we listen to our inner voice. He offers many interesting but tendentious examples to illustrate his theory, including Einstein, Darwin, Mozart and Temple Grandin. In the case of Darwin, Greene ignores the formative intellectual influences that shaped his thought, including the discovery of geological evolution with which he was familiar before his famous voyage. The author uses Grandin's struggle to overcome autistic social handicaps as a model for the necessity for everyone to create a deceptive social mask.

Readers unfamiliar with the anecdotal material Greene presents may find interesting avenues to pursue, but they should beware of the author's quirky, sometimes misleading brush-stroke characterizations.

Pub Date: Nov. 13, 2012

ISBN: 978-0-670-02496-4

Page Count: 320

Publisher: Viking

Review Posted Online: Sept. 12, 2012

Kirkus Reviews Issue: Oct. 1, 2012

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THE RIGHT STUFF

Yes: it's high time for a de-romanticized, de-mythified, close-up retelling of the U.S. Space Program's launching—the inside story of those first seven astronauts.

But no: jazzy, jivey, exclamation-pointed, italicized Tom Wolfe "Mr. Overkill" hasn't really got the fight stuff for the job. Admittedly, he covers all the ground. He begins with the competitive, macho world of test pilots from which the astronauts came (thus being grossly overqualified to just sit in a controlled capsule); he follows the choosing of the Seven, the preparations for space flight, the flights themselves, the feelings of the wives; and he presents the breathless press coverage, the sudden celebrity, the glorification. He even throws in some of the technology. But instead of replacing the heroic standard version with the ring of truth, Wolfe merely offers an alternative myth: a surreal, satiric, often cartoony Wolfe-arama that, especially since there isn't a bit of documentation along the way, has one constantly wondering if anything really happened the way Wolfe tells it. His astronauts (referred to as "the brethren" or "The True Brothers") are obsessed with having the "right stuff" that certain blend of guts and smarts that spells pilot success. The Press is a ravenous fool, always referred to as "the eternal Victorian Gent": when Walter Cronkite's voice breaks while reporting a possible astronaut death, "There was the Press the Genteel Gent, coming up with the appropriate emotion. . . live. . . with no prompting whatsoever!" And, most off-puttingly, Wolfe presumes to enter the minds of one and all: he's with near-drowing Gus Grissom ("Cox. . . That face up there!—it's Cox. . . Cox knew how to get people out of here! . . . Cox! . . ."); he's with Betty Grissom angry about not staying at Holiday Inn ("Now. . . they truly owed her"); and, in a crude hatchet-job, he's with John Glenn furious at Al Shepard's being chosen for the first flight, pontificating to the others about their licentious behavior, or holding onto his self-image during his flight ("Oh, yes! I've been here before! And I am immune! I don't get into corners I can't get out of! . . . The Presbyterian Pilot was not about to foul up. His pipeline to dear Lord could not be clearer"). Certainly there's much here that Wolfe is quite right about, much that people will be interested in hearing: the P-R whitewash of Grissom's foul-up, the Life magazine excesses, the inter-astronaut tensions. And, for those who want to give Wolfe the benefit of the doubt throughout, there are emotional reconstructions that are juicily shrill.

But most readers outside the slick urban Wolfe orbit will find credibility fatally undermined by the self-indulgent digressions, the stylistic excesses, and the broadly satiric, anti-All-American stance; and, though The Right Stuff has enough energy, sass, and dirt to attract an audience, it mostly suggests that until Wolfe can put his subject first and his preening writing-persona second, he probably won't be a convincing chronicler of anything much weightier than radical chic.

Pub Date: Sept. 24, 1979

ISBN: 0312427565

Page Count: 370

Publisher: Farrar, Straus and Giroux

Review Posted Online: Oct. 13, 2011

Kirkus Reviews Issue: Sept. 1, 1979

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