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MEMOIRS OF AN ADDICTED BRAIN

A NEUROSCIENTIST EXAMINES HIS FORMER LIFE ON DRUGS

From opium pipe to orbitofrontal cortex, a smoothly entertaining interplay between lived experience and the particulars of...

Developmental neuroscientist Lewis (Human Development and Applied Psychology/Radboud Univ., Netherlands) examines his odyssey from minor stoner to helpless, full-blown addict.

It all started when he was sent to boarding school in New England, where each student had their own host of problems and despair. But it was when he attended UC-Berkeley that he began to explore the world of drugs beyond the occasional bottle of cough syrup, to smoke marijuana and hash throughout the day and pop psychedelics a few times a week. As he now understands it, the drugs were talking to his brain "in the language of dopamine and peptides, neuromodulators and receptors," tricking the brain into releasing the neurochemicals of reward. As Lewis unspools one pungent drug episode after another, he capably knits into the narrative an accessible explanation of the neural activity that guided his behavior. Lewis chronicles his drug life shuffling from California to Malaysia to Calcutta to Canada, and he provides sharp place portraits intermixed with cringingly prismatic descriptions of intoxication and the bite of boredom, loneliness and shame. “I saw myself as a pathetic creature,” he writes, “a fool, completely obsessed with a stupid drug that I was impervious to the riot of life, the celebration of everyday sensation, that even the poorest people on earth were enjoying all around me." And though it is cheering that Lewis was finally able to shake the monkey off his back, it’s a shame that neuroscience couldn’t give him an answer about why: "I don't actually know the answer. I believe that further research in the neuroscience of addiction will help me get closer to finding it.”

From opium pipe to orbitofrontal cortex, a smoothly entertaining interplay between lived experience and the particulars of brain activity.

Pub Date: March 6, 2012

ISBN: 978-1-61039-147-4

Page Count: 336

Publisher: PublicAffairs

Review Posted Online: Dec. 18, 2011

Kirkus Reviews Issue: Jan. 1, 2012

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NIGHT

The author's youthfulness helps to assure the inevitable comparison with the Anne Frank diary although over and above the...

Elie Wiesel spent his early years in a small Transylvanian town as one of four children. 

He was the only one of the family to survive what Francois Maurois, in his introduction, calls the "human holocaust" of the persecution of the Jews, which began with the restrictions, the singularization of the yellow star, the enclosure within the ghetto, and went on to the mass deportations to the ovens of Auschwitz and Buchenwald. There are unforgettable and horrifying scenes here in this spare and sombre memoir of this experience of the hanging of a child, of his first farewell with his father who leaves him an inheritance of a knife and a spoon, and of his last goodbye at Buchenwald his father's corpse is already cold let alone the long months of survival under unconscionable conditions. 

The author's youthfulness helps to assure the inevitable comparison with the Anne Frank diary although over and above the sphere of suffering shared, and in this case extended to the death march itself, there is no spiritual or emotional legacy here to offset any reader reluctance.

Pub Date: Jan. 16, 2006

ISBN: 0374500010

Page Count: 120

Publisher: Hill & Wang

Review Posted Online: Oct. 7, 2011

Kirkus Reviews Issue: Jan. 15, 2006

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INTO THE WILD

A wonderful page-turner written with humility, immediacy, and great style. Nothing came cheap and easy to McCandless, nor...

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The excruciating story of a young man on a quest for knowledge and experience, a search that eventually cooked his goose, told with the flair of a seasoned investigative reporter by Outside magazine contributing editor Krakauer (Eiger Dreams, 1990). 

Chris McCandless loved the road, the unadorned life, the Tolstoyan call to asceticism. After graduating college, he took off on another of his long destinationless journeys, this time cutting all contact with his family and changing his name to Alex Supertramp. He was a gent of strong opinions, and he shared them with those he met: "You must lose your inclination for monotonous security and adopt a helter-skelter style of life''; "be nomadic.'' Ultimately, in 1992, his terms got him into mortal trouble when he ran up against something—the Alaskan wild—that didn't give a hoot about Supertramp's worldview; his decomposed corpse was found 16 weeks after he entered the bush. Many people felt McCandless was just a hubris-laden jerk with a death wish (he had discarded his map before going into the wild and brought no food but a bag of rice). Krakauer thought not. Admitting an interest that bordered on obsession, he dug deep into McCandless's life. He found a willful, reckless, moody boyhood; an ugly little secret that sundered the relationship between father and son; a moral absolutism that agitated the young man's soul and drove him to extremes; but he was no more a nutcase than other pilgrims. Writing in supple, electric prose, Krakauer tries to make sense of McCandless (while scrupulously avoiding off-the-rack psychoanalysis): his risky behavior and the rites associated with it, his asceticism, his love of wide open spaces, the flights of his soul.

A wonderful page-turner written with humility, immediacy, and great style. Nothing came cheap and easy to McCandless, nor will it to readers of Krakauer's narrative. (4 maps) (First printing of 35,000; author tour)

Pub Date: Jan. 1, 1996

ISBN: 0-679-42850-X

Page Count: 320

Publisher: Villard

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: Oct. 15, 1995

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