A stirring account of how important scientific research gets done.
Former Los Angeles Times national reporter McDermott (Perfect Soldiers: The 9/11 Hijackers: Who They Were, Why They Did It, 2006) tells the story of the driven neuroscientist Gary Lynch and his ongoing quest to discover the biochemical workings of memory.
Scientists have long been searching for the explanation of how memories are produced in the human brain and how they are stored and recalled. As McDermott explains in 101 Theory Drive—named after the street address of Lynch’s lab—Lynch has obsessively been trying to answer those complex questions for decades. With a chemist, he has also been working on drugs called ampakines, which could theoretically help improve memory function and restore the brain’s cognitive abilities—a potential boon for sufferers of Alzheimer’s and other neurological diseases. Starting in late 2004, McDermott spent nearly two years observing the work in the scientist’s lab. He chronicles the progress of Lynch’s research and provides an engaging portrait of the colorful but not-always-likable Lynch. The author ably explains highly technical concepts of neurology and breaks down complicated ideas in ways that general readers can easily understand. He’s equally at home describing the obsessive Lynch, who is portrayed as ambitious, brilliant and conversant on a dizzying array of subjects, but also impatient, full of self-regard and tough on his staff. The book opens with Lynch alone in his lab, annoyed that the rest of his team dared take a break between Christmas and New Year’s Day. McDermott also pays attention to key members of Lynch’s staff, such as neurophysiologist Eniko Kramar, whose workaholic devotion to Lynch’s work is described by her friends as “just short of self-destructive.”
A stirring account of how important scientific research gets done.Pub Date: April 6, 2010
ISBN: 978-0-375-42538-7
Page Count: 288
Publisher: Pantheon
Review Posted Online: Jan. 19, 2011
Kirkus Reviews Issue: Jan. 1, 2010
These are not hard and fast rules, but Meyer delivers important reading for those engaged in international business.
A helpful guide to working effectively with people from other cultures.
“The sad truth is that the vast majority of managers who conduct business internationally have little understanding about how culture is impacting their work,” writes Meyer, a professor at INSEAD, an international business school. Yet they face a wider array of work styles than ever before in dealing with clients, suppliers and colleagues from around the world. When is it best to speak or stay quiet? What is the role of the leader in the room? When working with foreign business people, failing to take cultural differences into account can lead to frustration, misunderstanding or worse. Based on research and her experiences teaching cross-cultural behaviors to executive students, the author examines a handful of key areas. Among others, they include communicating (Anglo-Saxons are explicit; Asians communicate implicitly, requiring listeners to read between the lines), developing a sense of trust (Brazilians do it over long lunches), and decision-making (Germans rely on consensus, Americans on one decider). In each area, the author provides a “culture map scale” that positions behaviors in more than 20 countries along a continuum, allowing readers to anticipate the preferences of individuals from a particular country: Do they like direct or indirect negative feedback? Are they rigid or flexible regarding deadlines? Do they favor verbal or written commitments? And so on. Meyer discusses managers who have faced perplexing situations, such as knowledgeable team members who fail to speak up in meetings or Indians who offer a puzzling half-shake, half-nod of the head. Cultural differences—not personality quirks—are the motivating factors behind many behavioral styles. Depending on our cultures, we understand the world in a particular way, find certain arguments persuasive or lacking merit, and consider some ways of making decisions or measuring time natural and others quite strange.
These are not hard and fast rules, but Meyer delivers important reading for those engaged in international business.Pub Date: May 27, 2014
ISBN: 978-1-61039-250-1
Page Count: 288
Publisher: PublicAffairs
Review Posted Online: April 15, 2014
Kirkus Reviews Issue: May 1, 2014
If the authors are serious, this is a silly, distasteful book. If they are not, it’s a brilliant satire.
The authors have created a sort of anti-Book of Virtues in this encyclopedic compendium of the ways and means of power.
Everyone wants power and everyone is in a constant duplicitous game to gain more power at the expense of others, according to Greene, a screenwriter and former editor at Esquire (Elffers, a book packager, designed the volume, with its attractive marginalia). We live today as courtiers once did in royal courts: we must appear civil while attempting to crush all those around us. This power game can be played well or poorly, and in these 48 laws culled from the history and wisdom of the world’s greatest power players are the rules that must be followed to win. These laws boil down to being as ruthless, selfish, manipulative, and deceitful as possible. Each law, however, gets its own chapter: “Conceal Your Intentions,” “Always Say Less Than Necessary,” “Pose as a Friend, Work as a Spy,” and so on. Each chapter is conveniently broken down into sections on what happened to those who transgressed or observed the particular law, the key elements in this law, and ways to defensively reverse this law when it’s used against you. Quotations in the margins amplify the lesson being taught. While compelling in the way an auto accident might be, the book is simply nonsense. Rules often contradict each other. We are told, for instance, to “be conspicuous at all cost,” then told to “behave like others.” More seriously, Greene never really defines “power,” and he merely asserts, rather than offers evidence for, the Hobbesian world of all against all in which he insists we live. The world may be like this at times, but often it isn’t. To ask why this is so would be a far more useful project.
If the authors are serious, this is a silly, distasteful book. If they are not, it’s a brilliant satire.Pub Date: Sept. 1, 1998
ISBN: 0-670-88146-5
Page Count: 430
Publisher: Viking
Review Posted Online: May 19, 2010
Kirkus Reviews Issue: July 15, 1998
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