The subject may be depressing, but it’s also important, and the author holds the reader’s interest to the end.
An intelligent and helpful tour of Alzheimer’s, by science writer Shenk (The End of Patience, 1999).
Since ancient times, senility has been considered a natural result of aging. Although the etiology was never clear, by the mid-20th century some blamed hardening of the arteries. In fact, although normal aging produces a mild memory deficit (mostly difficulty finding names), dementia is never normal. The author begins with the 1901 case described by neurologist Alois Alzheimer, who first noticed peculiar plaques and tangles of fibers dotting brain tissue in his microscopic exam. Victims of Alzheimer’s dementia begin by forgetting: Global brain function deteriorates (beginning with higher faculties such as judgment and personality) and eventually the patient becomes mute, bedridden, incontinent, and delirious. Alzheimer’s research attracted little attention in his day, but as decades passed, more and more plaques and fibers turned up in brain autopsies and, by the 1970s, it became clear that Alzheimer’s was not merely common, it was epidemic. Half a million Americans suffered in 1975; today the figure is closer to 5 million, making Alzheimer’s far more common than AIDS. Like AIDS it’s incurable; unlike AIDS no one knows how to prevent it. The author tells the story of famous historic victims (from Jonathan Swift to Ralph Waldo Emerson to Ronald Reagan) and describes how today’s patients deal with the disease. He also travels to interviews and conferences, where he reports the scientific debates now taking place over cause and treatment. Like most laymen, Shenk believes that the dramatic progress in our understanding of Alzheimer’s means that a good treatment is on the horizon, but no dramatic breakthrough seems imminent. Time alone will tell.
The subject may be depressing, but it’s also important, and the author holds the reader’s interest to the end.Pub Date: Sept. 4, 2001
ISBN: 0-385-49837-3
Page Count: 304
Publisher: Doubleday
Review Posted Online: May 19, 2010
Kirkus Reviews Issue: June 15, 2001
BOOK REVIEW
BOOK REVIEW
An absorbing, wide-ranging story of humans’ relationship with the water.
A study of swimming as sport, survival method, basis for community, and route to physical and mental well-being.
For Bay Area writer Tsui (American Chinatown: A People's History of Five Neighborhoods, 2009), swimming is in her blood. As she recounts, her parents met in a Hong Kong swimming pool, and she often visited the beach as a child and competed on a swim team in high school. Midway through the engaging narrative, the author explains how she rejoined the team at age 40, just as her 6-year-old was signing up for the first time. Chronicling her interviews with scientists and swimmers alike, Tsui notes the many health benefits of swimming, some of which are mental. Swimmers often achieve the “flow” state and get their best ideas while in the water. Her travels took her from the California coast, where she dove for abalone and swam from Alcatraz back to San Francisco, to Tokyo, where she heard about the “samurai swimming” martial arts tradition. In Iceland, she met Guðlaugur Friðþórsson, a local celebrity who, in 1984, survived six hours in a winter sea after his fishing vessel capsized, earning him the nickname “the human seal.” Although humans are generally adapted to life on land, the author discovered that some have extra advantages in the water. The Bajau people of Indonesia, for instance, can do 10-minute free dives while hunting because their spleens are 50% larger than average. For most, though, it’s simply a matter of practice. Tsui discussed swimming with Dara Torres, who became the oldest Olympic swimmer at age 41, and swam with Kim Chambers, one of the few people to complete the daunting Oceans Seven marathon swim challenge. Drawing on personal experience, history, biology, and social science, the author conveys the appeal of “an unflinching giving-over to an element” and makes a convincing case for broader access to swimming education (372,000 people still drown annually).
An absorbing, wide-ranging story of humans’ relationship with the water.Pub Date: April 14, 2020
ISBN: 978-1-61620-786-1
Page Count: 288
Publisher: Algonquin
Review Posted Online: Jan. 4, 2020
Kirkus Reviews Issue: Feb. 1, 2020
BOOK REVIEW
BOOK REVIEW
Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and...
A dense, absorbing investigation into the medical community's exploitation of a dying woman and her family's struggle to salvage truth and dignity decades later.
In a well-paced, vibrant narrative, Popular Science contributor and Culture Dish blogger Skloot (Creative Writing/Univ. of Memphis) demonstrates that for every human cell put under a microscope, a complex life story is inexorably attached, to which doctors, researchers and laboratories have often been woefully insensitive and unaccountable. In 1951, Henrietta Lacks, an African-American mother of five, was diagnosed with what proved to be a fatal form of cervical cancer. At Johns Hopkins, the doctors harvested cells from her cervix without her permission and distributed them to labs around the globe, where they were multiplied and used for a diverse array of treatments. Known as HeLa cells, they became one of the world's most ubiquitous sources for medical research of everything from hormones, steroids and vitamins to gene mapping, in vitro fertilization, even the polio vaccine—all without the knowledge, must less consent, of the Lacks family. Skloot spent a decade interviewing every relative of Lacks she could find, excavating difficult memories and long-simmering outrage that had lay dormant since their loved one's sorrowful demise. Equal parts intimate biography and brutal clinical reportage, Skloot's graceful narrative adeptly navigates the wrenching Lack family recollections and the sobering, overarching realities of poverty and pre–civil-rights racism. The author's style is matched by a methodical scientific rigor and manifest expertise in the field.
Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and Petri dish politics.Pub Date: Feb. 9, 2010
ISBN: 978-1-4000-5217-2
Page Count: 320
Publisher: Crown
Review Posted Online: Dec. 22, 2010
Kirkus Reviews Issue: Jan. 1, 2010
BOOK REVIEW
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