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UNTIL PROVEN SAFE

THE HISTORY AND FUTURE OF QUARANTINE

An infectiously appealing overview of efforts to contain the potentially infectious.

A captivating survey of the uses and abuses of quarantines, from the days of the Black Death to the lockdowns of Covid-19.

Journalists Manaugh and Twilley meld a global view of a timely subject with vividly detailed accounts of quarantines, whether of people or hazardous plants, animals, and chemicals such as nuclear waste. The authors show how—since the emergence of “lazarettos,” the quarantine hospitals of medieval Venice and other Adriatic ports—authorities have strived to contain dreaded hazards. Among many others, these have included the bubonic plague, yellow fever, tuberculosis, Ebola, and cholera. Yet some problems resist solutions. “Although the advent of advanced contagion modeling, location tracking, and data mining offer the promise of refining quarantine, rendering it so minimal and precise as to be almost imperceptible,” the authors write, “the use of those tools during COVID-19 has demonstrated that, in many ways, effective quarantine has changed remarkably little since its origins during the Black Death.” Persistent challenges include the tedium of isolation, the architectural rigors of designing suitable facilities, and the xenophobic use of quarantine “to obstruct the passage of undesirable immigrants at the border and stigmatize those who have already arrived.” For such risks, the authors propose fresh, sensible remedies such as a “bill of rights” for the quarantined. But a larger charm of this smart book lies in their ability to bring potentially dry topics to life. They profile the delightfully “obsessive” founder of the Disinfected Mail Study Circle (which tracks epidemics through postal evidence), and, after visiting a greenhouse near London, they note that cacao-plant diseases have contributed to a shrinking global chocolate supply that may lead to a “chocpocalypse.” Chocoholics, beware: One study found that in a decade or so, “a Hershey bar may well be as rare and expensive as caviar.”

An infectiously appealing overview of efforts to contain the potentially infectious.

Pub Date: July 20, 2021

ISBN: 978-0-374-12658-2

Page Count: 416

Publisher: MCD/Farrar, Straus and Giroux

Review Posted Online: April 27, 2021

Kirkus Reviews Issue: May 15, 2021

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THE GREATEST SENTENCE EVER WRITTEN

A short, smart analysis of perhaps the most famous passage in American history reveals its potency and unfulfilled promise.

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Words that made a nation.

Isaacson is known for expansive biographies of great thinkers (and Elon Musk), but here he pens a succinct, stimulating commentary on the Founding Fathers’ ode to “life, liberty, and the pursuit of happiness.” His close reading of the Declaration of Independence’s second sentence, published to mark the 250th anniversary of the document’s adoption, doesn’t downplay its “moral contradiction.” Thomas Jefferson enslaved hundreds of people yet called slavery “a cruel war against human nature” in his first draft of the Declaration. All but 15 of the document’s 56 signers owned enslaved people. While the sentence in question asserted “all men are created equal” and possess “unalienable rights,” the Founders “consciously and intentionally” excluded women, Native Americans, and enslaved people. And yet the sentence is powerful, Isaacson writes, because it names a young nation’s “aspirations.” He mounts a solid defense of what ought to be shared goals, among them economic fairness, “moral compassion,” and a willingness to compromise. “Democracy depends on this,” he writes. Isaacson is excellent when explaining how Enlightenment intellectuals abroad influenced the founders. Benjamin Franklin, one of the Declaration’s “five-person drafting committee,” stayed in David Hume’s home for a month in the early 1770s, “discussing ideas of natural rights” with the Scottish philosopher. Also strong is Isaacson’s discussion of the “edits and tweaks” made to Jefferson’s draft. As recommended by Franklin and others, the changes were substantial, leaving Jefferson “distraught.” Franklin, who emerges as the book’s hero, helped establish municipal services, founded a library, and encouraged religious diversity—the kind of civic-mindedness that we could use more of today, Isaacson reminds us.

A short, smart analysis of perhaps the most famous passage in American history reveals its potency and unfulfilled promise.

Pub Date: Nov. 18, 2025

ISBN: 9781982181314

Page Count: 80

Publisher: Simon & Schuster

Review Posted Online: Aug. 29, 2025

Kirkus Reviews Issue: Oct. 1, 2025

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WHEN BREATH BECOMES AIR

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...

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A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.

Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.

Pub Date: Jan. 19, 2016

ISBN: 978-0-8129-8840-6

Page Count: 248

Publisher: Random House

Review Posted Online: Sept. 29, 2015

Kirkus Reviews Issue: Oct. 15, 2015

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