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THE YEAR OF THE GENOME

A DIARY OF THE BIOLOGICAL REVOLUTION

There’s wisdom here to be sure, but it’s mingled with plenty of self-indulgence.

Thirty-four short medical/social-history essays by the erudite if somewhat dyspeptic physician-author (Democracy and DNA, 1996, etc.).

Weissmann’s “diary” runs in reverse order, beginning on October 2, 2001, and working backwards to April 3, 2000. The dating is as arbitrary as the title; essays have more to do with whatever news struck Weissmann’s fancy and launched his stream of medical consciousness. For example, the entry dated June 26, 2000—the day that Francis Collins and Craig Venter appeared with President Clinton to announce that the rival teams had all but completed mapping the human genome—takes the White House event as a jumping-off point for a discussion of laying the transatlantic cable in the19th century and the place of private enterprise in science and industry. Given the author’s respectable knowledge of the arts and sciences, this approach is often rather enlightening. Weissmann’s take on good friend Lewis Thomas’s life (January 17, 2001) emphasizes Thomas’s liberal stance against the rampant anti-Semitism that characterized most medical schools a generation ago. The essay for October 3, 2000 (during the week the FDA approved controversial “abortion pill” RU 486), encapsulates the history of research on the effects of steroid hormones on cell membranes and of prostaglandins on uterine muscle. April 3, 2000, cautions against mixing prescription drugs and herbal remedies (about which Weissmann is generally negative) but concludes with a marvelous history of aspirin. July 4, 2000, a paean to the late Patrick O’Brian, may intrigue fans with the suggestion that O’Brian heroes Aubrey and Maturin are modeled after Fitzroy and Darwin. Elsewhere, Weissmann reveals an impatience with the way things are, a sense that we haven’t come all that far, and even the suggestion that it might be best to go back, for example by reintroducing DDT as a means of preventing malaria.

There’s wisdom here to be sure, but it’s mingled with plenty of self-indulgence.

Pub Date: May 8, 2002

ISBN: 0-8050-7095-8

Page Count: 320

Publisher: Henry Holt

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: March 15, 2002

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A SHORT HISTORY OF NEARLY EVERYTHING

Loads of good explaining, with reminders, time and again, of how much remains unknown, neatly putting the death of science...

Bryson (I'm a Stranger Here Myself, 1999, etc.), a man who knows how to track down an explanation and make it confess, asks the hard questions of science—e.g., how did things get to be the way they are?—and, when possible, provides answers.

As he once went about making English intelligible, Bryson now attempts the same with the great moments of science, both the ideas themselves and their genesis, to resounding success. Piqued by his own ignorance on these matters, he’s egged on even more so by the people who’ve figured out—or think they’ve figured out—such things as what is in the center of the Earth. So he goes exploring, in the library and in company with scientists at work today, to get a grip on a range of topics from subatomic particles to cosmology. The aim is to deliver reports on these subjects in terms anyone can understand, and for the most part, it works. The most difficult is the nonintuitive material—time as part of space, say, or proteins inventing themselves spontaneously, without direction—and the quantum leaps unusual minds have made: as J.B.S. Haldane once put it, “The universe is not only queerer than we suppose; it is queerer than we can suppose.” Mostly, though, Bryson renders clear the evolution of continental drift, atomic structure, singularity, the extinction of the dinosaur, and a mighty host of other subjects in self-contained chapters that can be taken at a bite, rather than read wholesale. He delivers the human-interest angle on the scientists, and he keeps the reader laughing and willing to forge ahead, even over their heads: the human body, for instance, harboring enough energy “to explode with the force of thirty very large hydrogen bombs, assuming you knew how to liberate it and really wished to make a point.”

Loads of good explaining, with reminders, time and again, of how much remains unknown, neatly putting the death of science into perspective.

Pub Date: May 6, 2003

ISBN: 0-7679-0817-1

Page Count: 304

Publisher: Broadway

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: April 1, 2003

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LETTERS FROM AN ASTROPHYSICIST

A media-savvy scientist cleans out his desk.

Tyson (Astrophysics for People in a Hurry, 2017, etc.) receives a great deal of mail, and this slim volume collects his responses and other scraps of writing.

The prolific science commentator and bestselling author, an astrophysicist at the American Museum of Natural History, delivers few surprises and much admirable commentary. Readers may suspect that most of these letters date from the author’s earlier years when, a newly minted celebrity, he still thrilled that many of his audience were pouring out their hearts. Consequently, unlike more hardened colleagues, he sought to address their concerns. As years passed, suspecting that many had no interest in tapping his expertise or entering into an intelligent give and take, he undoubtedly made greater use of the waste basket. Tyson eschews pure fan letters, but many of these selections are full of compliments as a prelude to asking advice, pointing out mistakes, proclaiming opposing beliefs, or denouncing him. Readers will also encounter some earnest op-ed pieces and his eyewitness account of 9/11. “I consider myself emotionally strong,” he writes. “What I bore witness to, however, was especially upsetting, with indelible images of horror that will not soon leave my mind.” To crackpots, he gently repeats facts that almost everyone except crackpots accept. Those who have seen ghosts, dead relatives, and Bigfoot learn that eyewitness accounts are often unreliable. Tyson points out that extraordinary claims require extraordinary evidence, so confirmation that a light in the sky represents an alien spacecraft requires more than a photograph. Again and again he defends “science,” and his criteria—observation, repeatable experiments, honest discourse, peer review—are not controversial but will remain easy for zealots to dismiss. Among the instances of “hate mail” and “science deniers,” the author also discusses philosophy, parenting, and schooling.

A media-savvy scientist cleans out his desk.

Pub Date: Oct. 8, 2019

ISBN: 978-1-324-00331-1

Page Count: 272

Publisher: Norton

Review Posted Online: Sept. 1, 2019

Kirkus Reviews Issue: Sept. 15, 2019

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