CLONE

THE ROAD TO DOLLY AND THE PATH AHEAD

Not a quickie to exploit the news sensation of the year, Kolata's review of the before-during-and-aftermath of the cloning of a Scottish sheep is a well-researched account of critical events in the history of embryology and developmental biology. The feat was remarkable because Dolly was born from an egg whose nucleus had been replaced by the nucleus taken from the udder cell of an adult sheep. It was Kolata who broke the story in the New York Times last spring, swelling a media frenzy that led to public fear, congressional action, and bioethicist pronouncements, all the while elevating a modest Ian Wilmut to world-celebrity status. Yet only a year earlier Wilmut and his partner, Keith Campbell, had published an account of the birth of identical twin sheep-clones developed from late embryo cells that had already differentiated into something akin to skin cells. Why didn't that stun the readers of the august journal Nature? Here Kolata is on target in describing the trendiness and elitism of science: Molecular biologists and gene theorists, with their knockout mice and gene-of-the-week discoveries, pay scant heed to veterinarians pursuing commercial ends. In Wilmut's case those ends involved the potential for making animal clones that might carry useful human genes whose products—such as insulin—might be secreted in sheep breast milk. Also, the consensus was that there was a species barrier and that cloning of mammals was impossible. How that consensus came about is in itself a fascinating story of early pioneers interspersed with scandal, suspicions of fraud, and out-and-out contempt for the 1978 book In His Image, which purported to be the story of the cloning of a man. Kolata concludes with a thoughtful chapter on the ethical issues: At this stage there is no easy answer to where the line should be drawn in cloning experiments. All the more reason the book should appeal to readers who want to learn the facts and think for themselves. (Author tour)

Pub Date: Jan. 1, 1998

ISBN: 0-688-15692-4

Page Count: 288

Publisher: Morrow/HarperCollins

Review Posted Online: May 20, 2010

Kirkus Reviews Issue: Nov. 15, 1997

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A quirky wonder of a book.

WHY FISH DON'T EXIST

A STORY OF LOSS, LOVE, AND THE HIDDEN ORDER OF LIFE

A Peabody Award–winning NPR science reporter chronicles the life of a turn-of-the-century scientist and how her quest led to significant revelations about the meaning of order, chaos, and her own existence.

Miller began doing research on David Starr Jordan (1851-1931) to understand how he had managed to carry on after the 1906 San Francisco earthquake destroyed his work. A taxonomist who is credited with discovering “a full fifth of fish known to man in his day,” Jordan had amassed an unparalleled collection of ichthyological specimens. Gathering up all the fish he could save, Jordan sewed the nameplates that had been on the destroyed jars directly onto the fish. His perseverance intrigued the author, who also discusses the struggles she underwent after her affair with a woman ended a heterosexual relationship. Born into an upstate New York farm family, Jordan attended Cornell and then became an itinerant scholar and field researcher until he landed at Indiana University, where his first ichthyological collection was destroyed by lightning. In between this catastrophe and others involving family members’ deaths, he reconstructed his collection. Later, he was appointed as the founding president of Stanford, where he evolved into a Machiavellian figure who trampled on colleagues and sang the praises of eugenics. Miller concludes that Jordan displayed the characteristics of someone who relied on “positive illusions” to rebound from disaster and that his stand on eugenics came from a belief in “a divine hierarchy from bacteria to humans that point[ed]…toward better.” Considering recent research that negates biological hierarchies, the author then suggests that Jordan’s beloved taxonomic category—fish—does not exist. Part biography, part science report, and part meditation on how the chaos that caused Miller’s existential misery could also bring self-acceptance and a loving wife, this unique book is an ingenious celebration of diversity and the mysterious order that underlies all existence.

A quirky wonder of a book.

Pub Date: April 14, 2020

ISBN: 978-1-5011-6027-1

Page Count: 224

Publisher: Simon & Schuster

Review Posted Online: Jan. 2, 2020

Kirkus Reviews Issue: Feb. 1, 2020

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Jahren transcends both memoir and science writing in this literary fusion of both genres.

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LAB GIRL

Award-winning scientist Jahren (Geology and Geophysics/Univ. of Hawaii) delivers a personal memoir and a paean to the natural world.

The author’s father was a physics and earth science teacher who encouraged her play in the laboratory, and her mother was a student of English literature who nurtured her love of reading. Both of these early influences engrossingly combine in this adroit story of a dedication to science. Jahren’s journey from struggling student to struggling scientist has the narrative tension of a novel and characters she imbues with real depth. The heroes in this tale are the plants that the author studies, and throughout, she employs her facility with words to engage her readers. We learn much along the way—e.g., how the willow tree clones itself, the courage of a seed’s first root, the symbiotic relationship between trees and fungi, and the airborne signals used by trees in their ongoing war against insects. Trees are of key interest to Jahren, and at times she waxes poetic: “Each beginning is the end of a waiting. We are each given exactly one chance to be. Each of us is both impossible and inevitable. Every replete tree was first a seed that waited.” The author draws many parallels between her subjects and herself. This is her story, after all, and we are engaged beyond expectation as she relates her struggle in building and running laboratory after laboratory at the universities that have employed her. Present throughout is her lab partner, a disaffected genius named Bill, whom she recruited when she was a graduate student at Berkeley and with whom she’s worked ever since. The author’s tenacity, hope, and gratitude are all evident as she and Bill chase the sweetness of discovery in the face of the harsh economic realities of the research scientist.

Jahren transcends both memoir and science writing in this literary fusion of both genres.

Pub Date: April 5, 2016

ISBN: 978-1-101-87493-6

Page Count: 336

Publisher: Knopf

Review Posted Online: Jan. 5, 2016

Kirkus Reviews Issue: Jan. 15, 2016

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