Numerous books explain the genetic revolution now in progress; this one describes where it might lead, and it’s a wild ride.
“Hacking” is the unauthorized intrusion into a computer system, usually to alter its software. Some prefer the term “genetic engineering” to describe the process of changing an organism’s DNA to produce useful products or, more recently, correct defects. Futurist Metzl (Eternal Sonata, 2016, etc.), a senior fellow at the Atlantic Council who has also served in the State Department and the White House, maintains that this process will become so routine that most of us will not understand what’s happening and those that do might disapprove. In short, we will be hacked. One technique does not involve manipulating DNA. In today’s in vitro fertilization, doctors pick among multiple eggs, perhaps test for a few traits, usually absence of some defect, and implant a selection. Advances will enable a mother to produce huge numbers of eggs and doctors to test for countless traits—e.g., resistance to diseases, personality, even longevity—before implanting the best. The obvious next step is to remove defects or insert improved DNA into the genome. The new, Nobel-worthy CRISPR breakthrough makes this not only possible, but practical, and the first applications are emerging from the laboratory. Metzl’s explanation of how CRISPR works is no more comprehensible than those of earlier authors, but its dazzling possibilities are obvious. In future decades, advanced IVF will increasingly compete with sex as the primary way we procreate. Metzl devotes plenty of space to the fierce ethical debate, but the reality is that, given the choice, few parents are likely to choose “natural” reproduction and bear a child guaranteed to be less intelligent, talented, and healthy than otherwise.
A thoughtful, exciting, and mostly accessible account of how genetic manipulation will vastly improve our species. Miracles will happen, if not quite yet. Maybe in a few years....Pub Date: April 23, 2019
ISBN: 978-1-4926-7009-4
Page Count: 368
Publisher: Sourcebooks
Review Posted Online: Jan. 20, 2019
Kirkus Reviews Issue: Feb. 1, 2019
Categories: SCIENCE & TECHNOLOGY
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A Peabody Award–winning NPR science reporter chronicles the life of a turn-of-the-century scientist and how her quest led to significant revelations about the meaning of order, chaos, and her own existence.
Miller began doing research on David Starr Jordan (1851-1931) to understand how he had managed to carry on after the 1906 San Francisco earthquake destroyed his work. A taxonomist who is credited with discovering “a full fifth of fish known to man in his day,” Jordan had amassed an unparalleled collection of ichthyological specimens. Gathering up all the fish he could save, Jordan sewed the nameplates that had been on the destroyed jars directly onto the fish. His perseverance intrigued the author, who also discusses the struggles she underwent after her affair with a woman ended a heterosexual relationship. Born into an upstate New York farm family, Jordan attended Cornell and then became an itinerant scholar and field researcher until he landed at Indiana University, where his first ichthyological collection was destroyed by lightning. In between this catastrophe and others involving family members’ deaths, he reconstructed his collection. Later, he was appointed as the founding president of Stanford, where he evolved into a Machiavellian figure who trampled on colleagues and sang the praises of eugenics. Miller concludes that Jordan displayed the characteristics of someone who relied on “positive illusions” to rebound from disaster and that his stand on eugenics came from a belief in “a divine hierarchy from bacteria to humans that point[ed]…toward better.” Considering recent research that negates biological hierarchies, the author then suggests that Jordan’s beloved taxonomic category—fish—does not exist. Part biography, part science report, and part meditation on how the chaos that caused Miller’s existential misery could also bring self-acceptance and a loving wife, this unique book is an ingenious celebration of diversity and the mysterious order that underlies all existence.
A quirky wonder of a book.Pub Date: April 14, 2020
ISBN: 978-1-5011-6027-1
Page Count: 224
Publisher: Simon & Schuster
Review Posted Online: Jan. 1, 2020
Kirkus Reviews Issue: Feb. 1, 2020
Categories: GENERAL BIOGRAPHY & MEMOIR | BIOGRAPHY & MEMOIR | NATURE | SCIENCE & TECHNOLOGY
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Jahren transcends both memoir and science writing in this literary fusion of both genres.
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Award-winning scientist Jahren (Geology and Geophysics/Univ. of Hawaii) delivers a personal memoir and a paean to the natural world.
The author’s father was a physics and earth science teacher who encouraged her play in the laboratory, and her mother was a student of English literature who nurtured her love of reading. Both of these early influences engrossingly combine in this adroit story of a dedication to science. Jahren’s journey from struggling student to struggling scientist has the narrative tension of a novel and characters she imbues with real depth. The heroes in this tale are the plants that the author studies, and throughout, she employs her facility with words to engage her readers. We learn much along the way—e.g., how the willow tree clones itself, the courage of a seed’s first root, the symbiotic relationship between trees and fungi, and the airborne signals used by trees in their ongoing war against insects. Trees are of key interest to Jahren, and at times she waxes poetic: “Each beginning is the end of a waiting. We are each given exactly one chance to be. Each of us is both impossible and inevitable. Every replete tree was first a seed that waited.” The author draws many parallels between her subjects and herself. This is her story, after all, and we are engaged beyond expectation as she relates her struggle in building and running laboratory after laboratory at the universities that have employed her. Present throughout is her lab partner, a disaffected genius named Bill, whom she recruited when she was a graduate student at Berkeley and with whom she’s worked ever since. The author’s tenacity, hope, and gratitude are all evident as she and Bill chase the sweetness of discovery in the face of the harsh economic realities of the research scientist.
Jahren transcends both memoir and science writing in this literary fusion of both genres.Pub Date: April 5, 2016
ISBN: 978-1-101-87493-6
Page Count: 336
Publisher: Knopf
Review Posted Online: Jan. 4, 2016
Kirkus Reviews Issue: Jan. 15, 2016
Categories: BIOGRAPHY & MEMOIR | NATURE | SCIENCE & TECHNOLOGY
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