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LYME

THE FIRST EPIDEMIC OF CLIMATE CHANGE

Pfeiffer’s indignation and constant lacing of the text with tick names and numbers, disease counts, and tragic cases create...

An alert about the dangers of Lyme disease and other tick-borne infections.

Veteran investigative reporter Pfeiffer (Crazy in America: The Hidden Tragedy of our Criminalized Mentally Ill, 2007) lives in New York state, not far from the Connecticut town that gave its name to a bacterial infection a generation ago. Not only is there scant government research on Lyme disease, but the Centers for Disease Control and Prevention and the National Institutes of Health assert that the disease is easy to diagnose and cured with a course of antibiotics. They deny the existence of chronic Lyme disease, in which some patients experience painful joints and even heart disease or neurological problems, including cognitive declines. The agencies also inveigh against treating such patients with further courses of antibiotics. In page after page of data and interviews with patients, advocates, and researchers around the world, Pfeiffer builds a strong case: Diagnosis is not easy, many patients do not have the bull’s-eye rash associated with the tick bite, and the CDC’s diagnostic criteria are problematic. Worse, the prevalence of Lyme is rapidly growing worldwide. Thanks to global warming, tick species are spreading farther and finding ample numbers of small mammals to infect. The species that carry Lyme often carry other pathogens, a condition that seems to increase their vigor, while their saliva contains anti-coagulants, anesthetics, and immunosuppressive agents that enable the fiendishly small blood-suckers to hang on. Indeed, the author suggests that an anti-saliva agent might be more effective than an anti-Lyme vaccine. One difficulty with a vaccine is that the Lyme bacterium is a spirochete (like the agent for syphilis), a bug able to lie low and hide from the immune system in tissues as a persister.

Pfeiffer’s indignation and constant lacing of the text with tick names and numbers, disease counts, and tragic cases create a high emotional pitch that can be exhausting, but the basic facts she sets forth are credible, and they deserve immediate attention.

Pub Date: April 17, 2018

ISBN: 978-1-61091-844-2

Page Count: 288

Publisher: Island Press

Review Posted Online: Feb. 5, 2018

Kirkus Reviews Issue: Feb. 15, 2018

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WHY WE SWIM

An absorbing, wide-ranging story of humans’ relationship with the water.

A study of swimming as sport, survival method, basis for community, and route to physical and mental well-being.

For Bay Area writer Tsui (American Chinatown: A People's History of Five Neighborhoods, 2009), swimming is in her blood. As she recounts, her parents met in a Hong Kong swimming pool, and she often visited the beach as a child and competed on a swim team in high school. Midway through the engaging narrative, the author explains how she rejoined the team at age 40, just as her 6-year-old was signing up for the first time. Chronicling her interviews with scientists and swimmers alike, Tsui notes the many health benefits of swimming, some of which are mental. Swimmers often achieve the “flow” state and get their best ideas while in the water. Her travels took her from the California coast, where she dove for abalone and swam from Alcatraz back to San Francisco, to Tokyo, where she heard about the “samurai swimming” martial arts tradition. In Iceland, she met Guðlaugur Friðþórsson, a local celebrity who, in 1984, survived six hours in a winter sea after his fishing vessel capsized, earning him the nickname “the human seal.” Although humans are generally adapted to life on land, the author discovered that some have extra advantages in the water. The Bajau people of Indonesia, for instance, can do 10-minute free dives while hunting because their spleens are 50% larger than average. For most, though, it’s simply a matter of practice. Tsui discussed swimming with Dara Torres, who became the oldest Olympic swimmer at age 41, and swam with Kim Chambers, one of the few people to complete the daunting Oceans Seven marathon swim challenge. Drawing on personal experience, history, biology, and social science, the author conveys the appeal of “an unflinching giving-over to an element” and makes a convincing case for broader access to swimming education (372,000 people still drown annually).

An absorbing, wide-ranging story of humans’ relationship with the water.

Pub Date: April 14, 2020

ISBN: 978-1-61620-786-1

Page Count: 288

Publisher: Algonquin

Review Posted Online: Jan. 4, 2020

Kirkus Reviews Issue: Feb. 1, 2020

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THE IMMORTAL LIFE OF HENRIETTA LACKS

Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and...

A dense, absorbing investigation into the medical community's exploitation of a dying woman and her family's struggle to salvage truth and dignity decades later.

In a well-paced, vibrant narrative, Popular Science contributor and Culture Dish blogger Skloot (Creative Writing/Univ. of Memphis) demonstrates that for every human cell put under a microscope, a complex life story is inexorably attached, to which doctors, researchers and laboratories have often been woefully insensitive and unaccountable. In 1951, Henrietta Lacks, an African-American mother of five, was diagnosed with what proved to be a fatal form of cervical cancer. At Johns Hopkins, the doctors harvested cells from her cervix without her permission and distributed them to labs around the globe, where they were multiplied and used for a diverse array of treatments. Known as HeLa cells, they became one of the world's most ubiquitous sources for medical research of everything from hormones, steroids and vitamins to gene mapping, in vitro fertilization, even the polio vaccine—all without the knowledge, must less consent, of the Lacks family. Skloot spent a decade interviewing every relative of Lacks she could find, excavating difficult memories and long-simmering outrage that had lay dormant since their loved one's sorrowful demise. Equal parts intimate biography and brutal clinical reportage, Skloot's graceful narrative adeptly navigates the wrenching Lack family recollections and the sobering, overarching realities of poverty and pre–civil-rights racism. The author's style is matched by a methodical scientific rigor and manifest expertise in the field.

Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and Petri dish politics.

Pub Date: Feb. 9, 2010

ISBN: 978-1-4000-5217-2

Page Count: 320

Publisher: Crown

Review Posted Online: Dec. 22, 2010

Kirkus Reviews Issue: Jan. 1, 2010

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