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FRANCIS CRICK

DISCOVERER OF THE GENETIC CODE

A well-written addition to the publisher’s “Eminent Lives” series.

Short biography of a giant in molecular biology.

English science writer Ridley (Nature Via Nurture, 2003, etc.) posits that Francis Crick (1916–2004) was one of the greats, on par with Einstein, Darwin and Galileo. That claim may surprise those familiar with him primarily as James Watson’s coauthor on the famous paper describing DNA’s double helix. But the author, who knew Crick, argues that his work to establish the precise correspondence between specific DNA bases and the proteins they encode is a discovery as crucial as gravity or evolution. Ridley traces Crick’s origins from a middle-class family of modest means. (His grandfather, an amateur naturalist, once exchanged letters with Darwin.) Trained as a physicist, Crick worked on defense projects involving mines and torpedoes during WWII and came out of the war with no clear direction. He decided to try biology, with a quixotic notion of finding the key to life. Landing a slot at Cambridge University’s Cavendish Laboratory, he quickly established himself as a nonstop talker with an annoying laugh. Though a good theorist, he had problems with authority figures and was expected to leave once he finished his doctorate. Then Watson came to Cambridge; their joint assault on the structure of DNA is one of the best-known stories in modern science. Ridley covers the key details with keen insights into the pair’s relationship, then moves on to Crick’s role in solving the triplet code embedded in the DNA molecule. Nor does the text neglect his later work in both molecular biology and in attempting to solve the problem of consciousness. Crick comes across as a likable, highly motivated man without undue foibles; portraits of his coworkers and the period are also sharply drawn.

A well-written addition to the publisher’s “Eminent Lives” series.

Pub Date: June 1, 2006

ISBN: 0-06-082333-X

Page Count: 192

Publisher: N/A

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: March 1, 2006

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WHEN BREATH BECOMES AIR

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...

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A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.

Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.

Pub Date: Jan. 19, 2016

ISBN: 978-0-8129-8840-6

Page Count: 248

Publisher: Random House

Review Posted Online: Sept. 29, 2015

Kirkus Reviews Issue: Oct. 15, 2015

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THE PURSUIT OF HAPPYNESS

FROM MEAN STREETS TO WALL STREET

Well-told and admonitory.

Young-rags-to-mature-riches memoir by broker and motivational speaker Gardner.

Born and raised in the Milwaukee ghetto, the author pulled himself up from considerable disadvantage. He was fatherless, and his adored mother wasn’t always around; once, as a child, he spied her at a family funeral accompanied by a prison guard. When beautiful, evanescent Moms was there, Chris also had to deal with Freddie “I ain’t your goddamn daddy!” Triplett, one of the meanest stepfathers in recent literature. Chris did “the dozens” with the homies, boosted a bit and in the course of youthful adventure was raped. His heroes were Miles Davis, James Brown and Muhammad Ali. Meanwhile, at the behest of Moms, he developed a fondness for reading. He joined the Navy and became a medic (preparing badass Marines for proctology), and a proficient lab technician. Moving up in San Francisco, married and then divorced, he sold medical supplies. He was recruited as a trainee at Dean Witter just around the time he became a homeless single father. All his belongings in a shopping cart, Gardner sometimes slept with his young son at the office (apparently undiscovered by the night cleaning crew). The two also frequently bedded down in a public restroom. After Gardner’s talents were finally appreciated by the firm of Bear Stearns, his American Dream became real. He got the cool duds, hot car and fine ladies so coveted from afar back in the day. He even had a meeting with Nelson Mandela. Through it all, he remained a prideful parent. His own no-daddy blues are gone now.

Well-told and admonitory.

Pub Date: June 1, 2006

ISBN: 0-06-074486-3

Page Count: 320

Publisher: Amistad/HarperCollins

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: March 15, 2006

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