There is, of course, still no cure for Alzheimer’s. And journalist Castleman (Nature’s Cures, not reviewed, etc.), psychologist Gallagher-Thompson (an expert on caregiving for those with Alzheimer’s), and physician Naythons are realistic in their assessment of the current state of affairs: Although there are now medications that can slow progression of the disease, Alzheimer’s sufferers still follow an irreversible downward course. But “the grim mythology surrounding the disease has kept most Americans from noticing that in the years since Ronald Reagan’s diagnosis, real progress has been made in diagnosing, treating, managing, and preventing the disease.” To wit, the biology of Alzheimer’s is far better understood, risk factors are being identified, and some conditions thought to be Alzheimer’s have been recognized as reversible. New drug programs for arresting the disease are promising and have indicated new research directions. There is generally more support available for caregivers, and there are more innovative residential facilities for those with the disease. Interspersed with details on these developments are thorough case studies—the strength and perseverance of family caregivers are often awe-inspiring—and clearly devised plans for action, at whatever stage a family may find itself. Extensive resource lists are included. One of the best sources of help for Alzheimer’s since Mace and Rabins’s The 36-Hour Day. An absolute standout.