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LIFE SCRIPT

HOW THE HUMAN GENOME DISCOVERIES WILL TRANSFORM MEDICINE AND ENHANCE YOUR HEALTH

A creditable attempt to explain the directions that the new technology is moving in—and the possibilities of future benefits.

A rosy but necessarily imprecise overview of the potential impact of the sequencing of the humane genome on health and medicine, assembled largely from the author’s New York Times articles.

“The day will arrive when almost every human malady can be cured or addressed in some way,” writes Wade, a Times science reporter who has extensively covered the Human Genome Project. Although the title does not so indicate, about one third of his report is on the race to sequence the human genome and the competition between the international, public consortium of academic biologists, originally directed by Nobel Prize–winner James Watson, and the profit-making venture, Celera, headed by Craig Venter, to get there first. That story, peopled with ambitious, warring personalities, deserves a study of its own, and its purpose here seems to be to bolster to book-length the meager data thus far available on how knowledge of the human genome will change the biomedical sciences and medicine. Wade, who conducted extensive interviews with researchers, predicts that the next decade will see a host of new protein-based drugs, sophisticated new diagnostic tests, and new methods of treating diseases. He identifies two major approaches: first, scanning the normal genome to identify proteins of medical use; second, looking at variations in the genome to discover the roots of specific diseases, such as diabetes, heart disease, cancer, Alzheimer’s, multiple sclerosis, schizophrenia, osteoporosis, and osteoarthritis. The potential use of embryonic and adult stem cells to influence cell behavior and regenerate damaged or diseased tissues and possibly even whole organs is explored, as is the possible extension of the life span through genetic manipulation.

A creditable attempt to explain the directions that the new technology is moving in—and the possibilities of future benefits.

Pub Date: Sept. 6, 2001

ISBN: 0-7432-1605-9

Page Count: 208

Publisher: Simon & Schuster

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: July 1, 2001

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THE WORLD WITHOUT US

Weisman quietly unfolds his sobering cautionary tale, allowing us to conclude what we may about the balancing act that...

Nicely textured account of what the Earth would look like if humans disappeared.

Disaster movies have depicted the State of Liberty poking out from the ground and empty cities overgrown with trees and vines, but what would really happen if, for one reason or another, every single one of us vanished from the planet? Building on a Discover magazine article, Weisman (Journalism/Univ. of Arizona; An Echo in My Blood, 1999, etc.) addresses the question. There are no shocks here—nature goes on. But it is unsettling to observe the processes. Drawing on interviews with architects, biologists, engineers, physicists, wildlife managers, archaeologists, extinction experts and many others willing to conjecture, Weisman shows how underground water would destroy city streets, lightning would set fires, moisture and animals would turn temperate-zone suburbs into forests in 500 years and 441 nuclear plants would overheat and burn or melt. “Watch, and maybe learn,” writes the author. Many of his lessons come from past developments, such as the sudden disappearance of the Maya 1,600 years ago and the evolution of animals and humans in Africa. Bridges will fall, subways near fault lines in New York and San Francisco will cave in, glaciers will wipe away much of the built world and scavengers will clean our human bones within a few months. Yet some things will persist after we’re gone: bronze sculptures, Mount Rushmore (about 7.2 millions years, given granite’s erosion rate of one inch every 10,000 years), particles of everything made of plastic, manmade underground malls in Montreal and Moscow. In Hawaii, lacking predators, cows and pigs will rule.

Weisman quietly unfolds his sobering cautionary tale, allowing us to conclude what we may about the balancing act that nature and humans need to maintain to survive.

Pub Date: July 10, 2007

ISBN: 978-0-312-34729-1

Page Count: 304

Publisher: Dunne/St. Martin's

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: May 1, 2007

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THE GENIUS OF BIRDS

Ackerman writes with a light but assured touch, her prose rich in fact but economical in delivering it. Fans of birds in all...

Science writer Ackerman (Ah-Choo!: The Uncommon Life of Your Common Cold, 2010, etc.) looks at the new science surrounding avian intelligence.

The takeaway: calling someone a birdbrain is a compliment. And in any event, as Ackerman observes early on, “intelligence is a slippery concept, even in our own species, tricky to define and tricky to measure.” Is a bird that uses a rock to break open a clamshell the mental equivalent of a tool-using primate? Perhaps that’s the wrong question, for birds are so unlike humans that “it’s difficult for us to fully appreciate their mental capabilities,” given that they’re really just small, feathered dinosaurs who inhabit a wholly different world from our once-arboreal and now terrestrial one. Crows and other corvids have gotten all the good publicity related to bird intelligence in recent years, but Ackerman, who does allow that some birds are brighter than others, points favorably to the much-despised pigeon as an animal that “can remember hundreds of different objects for long periods of time, discriminate between different painting styles, and figure out where it’s going, even when displaced from familiar territory by hundreds of miles.” Not bad for a critter best known for bespattering statues in public parks. Ackerman travels far afield to places such as Barbados and New Caledonia to study such matters as memory, communication, and decision-making, the last largely based on visual cues—though, as she notes, birds also draw ably on other senses, including smell, which in turn opens up insight onto “a weird evolutionary paradox that scientists have puzzled over for more than a decade”—a matter of the geometry of, yes, the bird brain.

Ackerman writes with a light but assured touch, her prose rich in fact but economical in delivering it. Fans of birds in all their diversity will want to read this one.

Pub Date: April 12, 2016

ISBN: 978-1-59420-521-7

Page Count: 336

Publisher: Penguin Press

Review Posted Online: Feb. 16, 2016

Kirkus Reviews Issue: March 1, 2016

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